Nemours Biomedical Research
Located at Nemours/Alfred I. duPont Hospital for Children in Wilmington, Delaware, the CLIA-certified GI Clinical Lab is a pediatric lab that provides a variety of commonly used clinical lab services. We also accept samples for research studies and clinical trials.
The activity of disaccharidases, including lactase, maltase, sucrase, palatinase and glucoamylase, can be determined from an intestinal biopsy with approximately 2 to 5 mg wet weight.
Amylase, lipase, trypsin, chymotrypsin and elastase activities can be determined from duodenal fluid.
Gastric pepsin detected in the airway of patients is a specific and sensitive marker to assess pulmonary aspiration. The GI Clinical Lab at duPont Hospital for Children offers a sensitive, reliable enzymatic test to detect gastric pepsin in the airway samples. The assay has high specificity as it detects pepsin A that is exclusively expressed in the gastric mucosa. For more information on the research studies that used the assay or a similar enzymatic assay, please see the References listed below.
The GI Clinical Lab at duPont Hospital for Children also accepts samples for research studies and clinical trials. As part of the Gastroenterology Lab, we provide services to develop research projects for industry and research institutions.
Current research collaborators include Mayo Clinic, Florida; Cooper University Hospital, New Jersey; and Digestive Care, Inc., Pennsylvania.