Healthy kidneys filter waste from the blood, producing urine which normally flows only one direction: down the ureters and into the bladder. When something is wrong with the connection between the ureter and the bladder, the urine may flow back up (reflux) from the bladder to the ureters and at times to the kidneys.
If you have had VUR as a child, there is a chance that your children will have the condition. In addition, if one of your children has it, his or her brothers and sisters may also have the condition, too.
Infrequent or incomplete urination, as well as constipation, are also associated with VUR. Frequent urinary tract infections (UTIs) may indicate the presence of VUR.