Neural Correlates of the Y Chromosome in Autism: XYY Syndrome as a Genetic Model

Clinical Trial

Offered by: Nemours
Location: Delaware Valley

Trial Name

Neural Correlates of the Y Chromosome in Autism: XYY Syndrome as a Genetic Model

What is the trial about?

We want to do this study to learn more about three different conditions. These conditions are 47,XYY, 47,XXY (Klinefelter Syndrome) and Autism Spectrum Disorder. We want to know how children with these conditions are different from other children, including typically developing children.

Who can participate?

Boys between the ages of 2 and 17 years old including boys with 47,XYY, boys with Autism Spectrum Disorder and typically developing boys.

What is involved?

Your son will undergo a complete history and physical examination as well as a learning evaluation. This age-appropriate cognitive and behavioral evaluation assesses a number of areas of your child’s cognitive functioning. Some of these observational/interview tests will be videotaped for scoring. A report summarizing these results will be made available to you and/or to the child's teacher if you wish. Your son will also be asked to provide a blood sample, which will be used to assess hormonal development. We will also take photographs to document general appearance. These photographs will be taken of your child with his clothes on. These recorded materials will be used only for research, educational or regulatory purposes. If needed, the procedures will be administered over the course of two days.

There will be 1 blood draw from the child.

Contact Nemours Clinical Trials

Trial Name: Neural Correlates of the Y Chromosome in Autism: XYY Syndrome as a Genetic Model

Contact Information

(800) 354-5690
ClinicalTrials@nemours.org