Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children

Children's Oncology Group (COG)


Clinical Trial

Offered by: Nemours
Locations: Delaware Valley, Jacksonville, FL, Orlando, FL, Pensacola, FL

Trial Name

A Phase III Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children <36 Months Old With Intensive Induction Chemotherapy With Methotrexate Followed by Consolidation With Stem Cell Rescue vs. the Same Therapy Without Methotrexate

What is the trial about?

Compare the effects of induction therapy that includes methotrexate with induction therapy.

Who can participate?

< 36 months of age (3yrs).

What is involved?

Length of study is 6 months. In addition to standard cancer care treatment, the following tests will be taken: central review, genetic tests on tumor/blood samples.

Contact Nemours Clinical Trials

Trial Name: A Phase III Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children <36 Months Old With Intensive Induction Chemotherapy With Methotrexate Followed by Consolidation With Stem Cell Rescue vs. the Same Therapy Without Methotrexate

COG#: ACNS0334

Contact Information

(800) 354-5690
clinicaltrials@nemours.org