Treatments to Better Shrink High-Grade Gliomas

Children's Oncology Group (COG)


Clinical Trial

Offered by: Nemours
Locations: Delaware Valley, Jacksonville, FL, Orlando, FL, Pensacola, FL

Trial Name

A Randomized Phase II/III Study of Vorinostat and Local Irradiation OR Temozolomide and Local Irradiation OR Bevacizumab and Local Irradiation Followed by Maintenance Bevacizumab and Temozolomide in Children With Newly Diagnosed High-Grade Gliomas.

What is the trial about?

Treatments that will be better at getting rid of or shrinking high-grade gliomas.

Who can participate?

> 3 to < 22 yrs of age.

What is involved?

Length of study is 12-14 months. Standard cancer care including MRI and X-rays.

Contact Nemours Clinical Trials

Trial Name: A Randomized Phase II/III Study of Vorinostat and Local Irradiation OR Temozolomide and Local Irradiation OR Bevacizumab and Local Irradiation Followed by Maintenance Bevacizumab and Temozolomide in Children With Newly Diagnosed High-Grade Gliomas

COG#: ACNS0822

Contact Information

(800) 354-5690
clinicaltrials@nemours.org