Effects of Treatment During Radiation Therapy for Children With Diffuse Intrinsic Pontine Gliomas

Children's Oncology Group (COG)


Clinical Trial

Offered by: Nemours
Locations: Delaware Valley, Jacksonville, FL, Orlando, FL, Pensacola, FL

Trial Name

A Phase 1I2 Study of Suberoylanilide Hydroxamic Acid (SAHA, Vorinostat) and Local Irradiation, Followed by Maintenance SAHA in Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas (DIPG)

What is the trial about?

Find out what effects treatment with vorinostat during radiation therapy followed by maintenance therapy with vorinostat has on people with newly diagnosed DIPG.

Who can participate?

> 36 months and < 21 yrs of age.

What is involved?

Study length is up to 14 months. Standard cancer care.

Contact Nemours Clinical Trials

Trial Name: A Phase 1I2 Study of Suberoylanilide Hydroxamic Acid (SAHA, Vorinostat) and Local Irradiation, Followed by Maintenance SAHA in Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas (DIPG)

COG#: ACNS0927

Contact Information

(800) 354-5690
clinicaltrials@nemours.org