Dose Escalation Study in Pediatric Patients With Relapsed or Refractory Solid Tumors

Children's Oncology Group (COG)


Clinical Trial

Offered by: Nemours
Locations: Delaware Valley, Jacksonville, FL

Trial Name

A Phase 1 Dose Escalation Study of REOLYSIN, a Replication Competent Reovirus, in Pediatric Patients With Relapsed or Refractory Solid Tumors

What is the trial about?

To find the highest safe dose of REOLYSIN that can be given without causing severe side effects; To learn what kind of side effects REOLYSIN can cause.

Who can participate?

> 3yrs and < 21 yrs of age.

What is involved?

Length of study up to 12 months. Standard cancer care including: Physical exam; Vital signs; Blood tests; Urine tests; Stool tests; Saliva tests; ECHO and EKG.

Contact Nemours Clinical Trials

Trial Name: A Phase 1 Dose Escalation Study of REOLYSIN, a Replication Competent Reovirus, in Pediatric Patients With Relapsed or Refractory Solid Tumors

COG#: ADVL1014

Contact Information

(800) 354-5690
clinicaltrials@nemours.org