A Clinical Trial to Evaluate Safety of Sitagliptin in Pediatric Patients With Type 2 Diabetes

Clinical Trial

Offered by: Nemours Children's Specialty Care, Jacksonville
Location: Jacksonville, Fla.

Trial Name

A Clinical Trial to Evaluate Safety of Sitagliptin in Pediatric Patients With Type 2 Diabetes.

What is the trial about?

To learn if sitagliptin is safe in children 10 – 17 years old. This study will determine the effect of treatment with sitagliptin compared to placebo on A1c.

Who can participate?

Children ages 10-17 with Type 2 Diabetes. 

What is involved?

Your child will visit the study doctor about 10 times over 56 weeks. Your child will be randomly assigned to a treatment group below.

Sitagliptin group — 1 tablet of Sitagliptin before the morning meal and 2 tablets of metformin-placebo before the morning and evening meals.

Placebo group — 1 tablet Sitagliptin-placebo before the morning meal and 2 tablets of metformin-placebo before the morning and evening meals.

If your child is currently taking insulin, their dosage of insulin will remain the same while they are participating in the study unless a study doctor feels a change to their insulin dose is required.

Study will require 7 blood draws, 2 bone age X-rays and 3 EKGs.

Contact Nemours Clinical Trials

Trial Name: Sitagliptin in Type 2 Diabetes With Inadequate Glycemic Control

Contact Information

(800) 354-5690
ClinicalTrials@nemours.org