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Liver Tumors

Nemours Center for Cancer and Blood Disorders in the Delaware Valley and Florida

Locations & Doctors Who Treat Liver Tumors

 
Delaware

Wilmington

Nemours/Alfred I. duPont Hospital for Children

1600 Rockland Road
Wilmington, DE 19803
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For Appointments: (800) 416-4441

Doctors Who Treat Liver Tumors at This Location

 
New Jersey

Voorhees

Nemours duPont Pediatrics, Voorhees

443 Laurel Oak Road
Therapy Services (Suite 200)
Pediatric Specialty Services (Suite 230)
Voorhees, NJ 08043
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For Appointments: (800) 416-4441

Hours: Fourth Friday each month; 9 a.m. to 4 p.m.
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Doctors Who Treat Liver Tumors at This Location

 
Pennsylvania

Philadelphia

Nemours duPont Pediatrics, Philadelphia

833 Chestnut St. E., Suite 300
Philadelphia, PA 19107
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For Appointments: (800) 416-4441

Hours: Monday–Friday: 8 a.m. to 5 p.m.
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Doctors Who Treat Liver Tumors at This Location


Lancaster

Nemours duPont Pediatrics, Lancaster

2128 Embassy Drive, Suite A
Lancaster, PA 17603
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For Appointments: (800) 416-4441

Hours: Hours vary; please call
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Doctors Who Treat Liver Tumors at This Location

 
Florida

Orlando

Nemours Children's Hospital, Orlando

13535 Nemours Parkway
Orlando, FL 32827
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For Appointments: (407) 650-7715

Doctors Who Treat Liver Tumors at This Location


Nemours Children's Specialty Care, Orlando

1717 S. Orange Ave.
Orlando, FL 32806
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For Appointments: (407) 650-7715

Hours: Monday–Friday, 8 a.m. to 5 p.m.
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Doctors Who Treat Liver Tumors at This Location

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Melbourne

Nemours Children's Specialty Care, Melbourne

1270 N. Wickham Road
Melbourne, FL 32935
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For Appointments: (407) 650-7715

Hours: Monday–Friday: 8 a.m. to 5 p.m.
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Doctors Who Treat Liver Tumors at This Location

To find out which providers serve this location, please call the main number above.

Jacksonville

Nemours Children's Specialty Care, Jacksonville

807 Children’s Way
Jacksonville, FL 32207
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For Appointments: (904) 697-3789

Hours: Monday–Friday, 8 a.m. to 5 p.m.
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Doctors Who Treat Liver Tumors at This Location


Pensacola

Nemours Children's Specialty Care, Pensacola

5153 N. Ninth Ave.
Pensacola, FL 32504
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For Appointments: (850) 505-4790

Hours: Monday–Friday, 8 a.m. to 5 p.m. (Central Time)
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Doctors Who Treat Liver Tumors at This Location

About Liver Tumors

Lauren was diagnosed with stage 4 heptoblastoma when she was 19 months old.

The liver performs important functions such as filtering harmful toxins in the blood for elimation, storing the sugars the body uses for energy, and helping digest fats. Tumors that form in the liver are rare in children. Although liver cancer can be benign (noncancerous) or malignant (cancerous), both kinds may grow and affect healthy liver tissue.

In the United States, each year about one child in a million is diagnosed with a malignant liver tumor (also called a “hepatic tumor”). The cause of pediatric liver tumors is largely unknown, but studies show that certain familial (genetic) medical conditions (such as nonalcohol related cirrhosis and problems with metabolism) and infections (like hepatitis) can contribute.

Our experienced pediatric hepatologists (liver specialists) work together with our renowned oncologists (cancer doctors) and researchers at the Nemours Center for Cancer and Blood Disorders (a Children’s Oncology Group member institution) to diagnose and treat liver tumors in children. We see kids of all ages with newly diagnosed childhood liver tumors (both malignant and benign), as well as advanced and complex tumors that have relapsed or are unresponsive to treatment.


Types of Childhood Liver Tumors We Treat

Malignant Childhood Liver Tumors 

Two types of malignant (cancerous) childhood liver tumors make up two-thirds of all liver cancer diagnoses: hepatoblastomas and hepatocellular carcinomas. 

Hepatoblastomas 

Hepatoblastomas are the most common form of liver tumors diagnosed in early childhood (around 2 or 3 years old). Hepatoblastomas have been linked to low birth weight (prematurity) and rare genetic health problems such as Beckwith-Wiedemann syndrome or familial colonic polyposis. These tumors rarely metastasize (or spread) beyond the liver.

Hepatocellular Carcinomas

Hepatocellular carcinomas are rarely found in children, but can present in adolescence through young adulthood (around 12 to 20 years old). These aggressive liver tumors may metastasize to other parts of the body (usually the lungs and nearby lymph nodes) and are commonly found in children with recurring liver infections or metabolic disorders.   


Benign Liver Tumors in Children

The types of benign (noncancerous) liver tumors include:
  • hemangiomas (most common benign liver tumor that occurs within a few months of birth; hemangioendotheliomas, a subtype, are found in infants)
  • hamartomas (also called “mesenchymal hamartomas” in children, are masses/malformations that grow mostly in the right lobe of the liver) 
  • focal nodular hyperplasia and hepatic adenomas (found in adolescent girls usually due to high estrogen production and oral contraceptives)

Diagnosing Liver Tumors in Children

Signs & Symptoms of Liver Tumors

Symptoms of pediatric liver tumors usually begin when the tumor is large, and can include:

  • swelling or pain in the abdomen (with or without a mass)
  • jaundice (yellowing of the skin or eyes)
  • back pain
  • loss of appetite
  • weight loss
  • nausea
  • vomiting 

Testing & Evaluations

If your child has a possible liver tumor, Nemours’ experienced cancer care team works together to appropriately diagnose and stage the disease through a variety of tests and procedures, including:

  • thorough physical examination and medical history
  • blood tests (alpha-fetoprotein, or “AFP”)
  • medical imaging (X-ray, MRI, PET scan, MIBG scan, ultrasound)
  • diagnostic biopsy (via surgery or minimally invasive interventional radiology)

Treating & Caring for Children With Liver Tumors

Your Child's Comprehensive Liver Tumors Care Team

If we discover a liver tumor, our multidisciplinary (collaborative) team plans the most effective treatment personalized to your child’s needs. In addition to an experienced, compassionate cancer coordinator (a nurse who provides your child and family support, education and care coordination), Nemours’ pediatric cancer teams include:

  • oncologists (cancer specialists)
  • hematologists (blood specialists)
  • surgeons (general surgery and solid organ transplantation)
  • heptologists (liver specialists)
  • gastroenterologists (digestive specialists)
  • pathologists (diagnose diseases by examining body tissues, fluids and organs)
  • geneticists (perform genetic counseling and testing)
  • radiologists (diagnose diseases through medical imaging)
  • radiation oncologists (specialists in radiation therapy treatment)
  • interventional radiologists (perform image-guided minimally-invasive procedures)
  • behavioral health specialists (psychologists and psychiatrists)
  • registered dieticians (nutrition specialists)
  • oncology nurses (registered nurses specializing in cancer)  

Your care team is here to provide your family with ongoing support and follow-up. We always include you in the entire process, because we truly believe in the healing power of families, and that you know your child best. 

Learn More About Nemours’ Pediatric Cancer Care Teams in Your Area »


Innovative Childhood Liver Tumor Treatment at Nemours

At Nemours, we offer advanced and innovative childhood cancer treatments and approaches (called “modalities”) that aren’t available at other children’s hospitals. Treating pediatric liver tumors depends on the type and stage and can include a combination of one or more of the following modalities:

For your child’s overall health and wellness, we also prescribe:

Learn More About Pediatric Cancer Treatment at Nemours »

Additional Resources & Support for Families

 
Nemours Support Services

Dealing with childhood cancer is difficult for your child and family. But you don’t have to go through it alone. Nemours provides an array of support services that begin on the very first day we meet, and continues throughout your journey because at Nemours, your child and family become one of our own.

Our services include: 
  • patient and family education
  • social work
  • mental health counseling
  • Child Life services
  • creative therapy
  • support groups

Get Comprehensive Patient Education & Support Resources »

Appointments & Referrals

Delaware, Pennsylvania & New Jersey

(800) 416-4441


Florida
Jacksonville Area

(904) 697-3789

Orlando Area

(407) 650-7715

Pensacola Area

(850) 505-4790

Learn About Our Locations »


International
Patients

+1 (302) 651-4993

Our Goal: A Better Tomorrow

At the Nemours Center for Cancer and Blood Disorders, we strive to maximize every child's quality of life — today and for many tomorrows. Watch Video »

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