Patent Ductus Arteriosus (PDA)

Heart With Patent Ductus Arteriosus (PDA)

An animation of how a heart with patent ductus arteriosus (PDA) functions.

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The ductus arteriosus is a normal connection in utero between the pulmonary artery and the aorta. Since the lungs are still developing, the baby receives oxygenated blood from the mother during pregnancy. The ductus arteriosus allows the greater part of the oxygenated blood to bypass the non-aerated lungs by flowing directly from the pulmonary artery to the aorta. After the baby is born and begins breathing, hormonal changes occur causing the ductus arteriosus to close. A patent ductus arteriosus, or PDA, is when this connection does not close as it normally should. If the ductus remains open, the direction of flow reverses and some of the oxygen-rich blood from the aorta flows to the pulmonary artery and into the lungs. This may cause an excessive amount of blood flow to the lungs.

There are two reasons that necessitate the closure of a PDA. The first is the size of the ductus, which in turn determines the volume of extra blood being directed to the lungs. A large volume overload may result in enlargement of the heart and over time heart failure. The second reason is to avoid the risk of developing an infection in the heart known as endocarditis. Approximately, one-eighth of patients with a PDA will develop endocarditis. This increases mortality by 50% whereas the risk of surgery is almost zero.

Depending on the size of the ductus, a PDA may be treated in one of two ways. If the ductus is large, the child may require surgery that involves closing off the ductus with a clamp or suture. However, in many cases, the PDA can be closed using a spring coil or a synthetic plug. Both devices are introduced through a heart catheter, which is passed through a vein in the leg that leads up to the heart.

How Does Patent Ductus Arteriosus (PDA) Differ From Normal Cardiac Anatomy?

If your child has patent ductus arteriosus (PDA) or another congenital heart defect, there's usually something wrong with the structure of his or her heart.

Learn More About How Patent Ductus Arteriosus (PDA) Differs From Normal Cardiac Anatomy

Heart with Normal Cardiac Anatomy

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When your child has a congenital heart defect, there's usually something wrong with the structure of his or her heart's structure.

The heart is composed of four chambers. The two upper chambers, known as atria, collect blood as it flows back to the heart. The two lower chambers, known as ventricles, pump blood with each heartbeat to the two main arteries (the pulmonary artery and the aorta). The septum is the wall that divides the heart into right and left sides. The atrial septum separates the right and left atria; likewise, the ventricular septum separates the two ventricles.

There are four valves that control the flow of blood through the heart. These flap-like structures allow blood to flow in only one direction. The tricuspid and mitral valves, also known as the atrioventricular valves, separate the upper and lower chambers of the heart. The aortic and pulmonary valves, also known as the arterial valves, separate the ventricles from the main arteries. Oxygen-depleted blood returns from the body and drains into the right atrium via the superior and inferior vena cavas. The blood in the right atrium then passes through the tricuspid valve and enters the right ventricle.

Next, the blood passes through the pulmonary valve, enters the pulmonary artery, and travels to the lungs where it is replenished with oxygen. The oxygen-rich blood returns to the heart via the pulmonary veins, draining into the left atrium. The blood in the left atrium passes through the bicuspid, or mitral, valve and enters the left ventricle.

Finally, the oxygen-rich blood flows through the aortic valve into the aorta and out to the rest of the body.

A to Z: Patent Ductus Arteriosus (PDA)

A to Z: Patent Ductus Arteriosus (PDA)

May also be called: PDA

Patent ductus arteriosus (DUK-tus ar-tir-ee-OH-sus), or PDA, is a condition in newborn babies in which a fetal blood vessel in the heart fails to close as it normally should.

More to Know

The ductus arteriosus (DA) is a normal blood vessel that connects two major arteries — the aorta and the pulmonary artery — that carry blood away from the heart in a developing fetus. The DA diverts blood away from the lungs, sending it directly to the body. The lungs are not used while a fetus is in the amniotic fluid because the baby gets oxygen directly from the mother's placenta. When a newborn breathes and begins to use the lungs, the DA is no longer needed and usually closes during the first 2 days after birth.

If the DA fails to close, a patent (meaning "open") ductus arteriosus is the result. Oxygen-rich blood from the aorta mixes with oxygen-poor blood in the pulmonary artery, and too much blood flows into the lungs.

Babies with a PDA may have poor feeding, poor growth, difficulty breathing, excessive sweating, fatigue, or a bluish color to the skin. A larger PDA puts a strain on the heart and increases blood pressure in the pulmonary arteries. A smaller PDA may not cause any symptoms.

Keep in Mind

In the vast majority of babies who have a small PDA but otherwise normal heart, the PDA will shrink and go away on its own in the first few days of life. Other PDAs may close on their own within the first year of a baby's life.

Large PDAs are rare, but can strain the heart and cause other problems. Medications, catheter-based procedures, or surgery may be used to close these PDAs.

All A to Z dictionary entries are regularly reviewed by KidsHealth medical experts.

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Date reviewed: September 26, 2016