Liver Transplant

boy holding hands with parent

If your child has end-stage liver disease and needs a transplant, our Nemours transplant experts can provide the care your child requires – and the hope your family is looking for.

As a team not only have we performed numerous successful liver transplants, at the Nemours/Alfred I. duPont Hospital for Children (AIDHC) we’re one of the best in the nation based on our clinical outcomes for liver transplantation (when considered according to how complex a case is and how severe the illness). But our real success is measured by all of the children who go on to lead normal, happy, healthy lives after their liver transplant. Seeing the kids we treat improve and thrive as they grow is the highest honor for what we do.

Liver transplantation is a technically demanding operation. After all, the liver is the largest solid organ in the body and has multiple purposes, including the most important: cleaning the blood, producing an important digestive liquid called “bile,” and storing energy from the foods we eat in the form of a sugar called “glycogen.”

But our Nemours transplant team is made up a family of highly experienced, qualified, caring health professionals who dedicate their lives to helping children just like yours. We’ll guide you through the entire transplant process, from the minute you’re told your child needs a liver transplant to long after you take your child home after the transplant.

Types of Liver Donors

Your child may be able to get a donated liver in one of two ways – from a:

  • living donor – either a relative (this is called a “living related donor”) or another unrelated adult
  • deceased (or cadaver) donor – the most common way, donated by a healthy adult or child who became critically ill and died of this illness (after the person or his or her guardians agreed to donate the organs in the event of a sudden death) 

 

At Nemours, we were early adopters of living-related donor procedures, which allow a living relative to donate a segment of the liver for transplantation. If the living donor (related or not) is cleared for donating the organ, he or she will undergo surgery to remove part (not all) of the liver. How much of the donor’s liver is removed depends on the size of the child getting the liver transplant. Most living donors for pediatric patients donate what’s called the “left-lateral segment” of the liver, which is a small piece of the organ that makes up about 30% of the liver mass.

Adults who donate a part of their liver can lead healthy lives because the residual liver will regenerate to a size close to that of the original liver.

Of course, not every child can get a living liver donor, but this technique does make it possible for more children to receive a transplant as soon as possible – and increases their chances of long-term survival after the transplant. If there’s no willing and compatible living donor your child will have to wait until a liver becomes available from the local and national organ donor waiting lists.

How It Works

Once your child gets the team’s OK after all of the required evaluations, tests, and consultations  are completed (see Solid Organ Transplant for more information) and a deceased or living donor match is found, your child is ready for the transplant surgery.

During the transplant, the entire liver of the child receiving the transplant is removed. Then the new liver (or liver portion) is attached in place of the old liver with connections to the important blood vessels. The surgery generally takes 4 to 8 hours. Your child will be admitted to the Pediatric Intensive Care Unit after the procedure is over. He or she will be closely monitored during this stay and, when ready, will be transferred to a more relaxed setting on the regular inpatient area.

Most children recover from the surgical procedure in a few days. They’re able to eat and move around without much assistance. In a few weeks, they can even return to an active life. And our Nemours team members will work with you and your child not just right after you’re able to go home – but for the long-term, to make sure your child is healthy now and far into the future.

To find out more details about getting a liver transplant at Nemours, see Solid Organ Transplant and Transplant Programs.

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Liver Transplant

Helping Liver Transplant Patients Live—and Live Longer

At the Nemours/Alfred I. duPont Hospital for Children (AIDHC), our Solid Organ Transplant specialists oversee one of the largest pediatric liver and kidney transplant programs in the country. Our liver transplant outcomes make us one of the best (based on how complex the case is and how severe the child’s illness). In fact, our survival rate (that’s the number of kids alive after their transplant) is better than the national average.


About This Graph

When you look at statistics about survival rates for liver transplants, there are two kinds of donors to understand:

Living donor: When someone living donates part of his or her liver to the child needing a transplant. A “living related donor” is a living relative who donates a segment of the liver.

Deceased donor: When someone dies and gives his or her entire liver to a transplant patient (by being an organ donor).

Typically, survival rates are looked at over various periods of time after the transplant. Here’s how we, at duPont Hospital for Children, did compared to the national average (or benchmark):

  • 3 months after transplant: All (100%) of the children who received a liver transplant here from a deceased donor survived—compared to the national average of 93%. For living donors, we’re at 97% survival, versus the national average of 95%. (The national average is based on the 2009 Annual Report from the Organ Procurement and Transplant Network/OPTN and the Scientific Registry of Transplant Recipients/SRTR.)
  • 12 months (1 year) after transplant: Our survival rate is 92% for deceased donors and 90% for living donors—compared to the national average of 90% for both.
  • 5 years after transplant: Our rate is 90% for kids who received a transplant from either a deceased or living donor, compared to the much lower national average of 83.8% for deceased donors and 83.1% for living donors.

But we aren’t just focused on helping your child live—we’re concerned about your child’s quality of life and how your child feels and functions now and over the long-term. Our real success is measured by all of the kids who go on to lead healthy lives after their liver transplants. Seeing the kids we treat improve and thrive as they grow is the highest honor for what we do.

How We Do It

Organ transplants are complex and often require the care of multiple physicians and health professionals. Of course, every child’s disease, prognosis, and treatment plan are very different. But at Nemours Solid Organ Transplant Program, we treat each and every patient we see with the same level of high-quality care to help give every child the very best outcome we can. How? Well, we:

  • Were one of the first in our area to do living-related donor procedures, which allow a living relative to donate a segment of their liver for transplantation—and makes it possible for more children to receive a transplant as soon as possible.
  • Work together as one coordinated, highly skilled, dedicated team. Our physicians, nurses, transplant coordinator, and other members from across different specialties pool their knowledge, skills, expertise, and experience to best manage patients with complex liver disease. And we consider you, the parent, an important member of our team—always keeping you informed and involved. We take pride in offering family-centered care.
  • Offer comprehensive therapy that helps kids recuperate faster. In fact, our length of stay in the hospital is shorter than national averages—many of our transplant patients are back home within 3 to 4 weeks after their transplant.
  • Follow all of our patients very closely post-transplant, both as inpatients and outpatients.
  • Use cutting-edge technology to keep everyone on the same page about your child’s condition and care—at the exact same time. With just a few clicks, everyone on the transplant team can access your child’s entire electronic health record (or EHR) from all of the different Nemours specialties and locations. And you can keep track of your child’s care, too (prescriptions, tests, appointments, etc.) through an innovative, customized health record (called MyNemours) that you can access from home—privately, safely, and securely—and through our new mobile app, MyChart.

At Nemours, we guide your family through every step of your transplant journey. Our goal—our sincere hope—is that your child will experience continued improvement and progress that opens the doors for a long lifetime of possibilities.

Learn More

Get more information about our top-notch transplant care:

Read this inspiring story about one of our transplant patients, Bella Rose.

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