Sickle Cell Disease

1 in 625 African-Americans are born with sickle cell anemia. Disease symptoms include paleness in the skin and lips.

As a parent, hearing your child has sickle cell disease can be overwhelming. But with early diagnosis, progressive treatment, and regular follow-up care, Nemours' board-certified pediatric hematologists — doctors who treat blood disorders — can help your child manage sickle cell anemia symptoms and live an active and productive life.

Read More About Sickle Cell Disease

Sickle cell disease or sickle cell anemia is a genetically inherited blood disorder, detected through a blood test. The disease is passed down from both parents who carry an altered hemoglobin gene, which causes their red blood cells to take on an abnormal (sickle) shape rather than the normal, smooth disc shape.


Nemours duPont Pediatrics, Milford

Teal Creek Plaza
703 N. Dupont Blvd.
Milford, DE 19963
Get Map & Directions »

For Appointments: (302) 422-4559

Hours: Monday through Wednesday 8 a.m. to 8 p.m.
Thursday and Friday 8 a.m. to 5 p.m.

Coming in spring of 2015, evening hours will be offered until 8 p.m. Monday through Thursday.

Learn More About This Location »

Appointments: Quarterly, third Wednesday of the month.
Call for day and times at (302) 651-5500.

View Doctors
To find out which physicians serve this location, please call the main number above.
What to Bring
  • photo ID
  • medical and pharmacy insurance cards
  • preferred pharmacy name and phone number
  • names and dosage of all medications, including over-the-counter medication, your child is currently taking
  • guardianship and custody papers, if a legal guardian rather than a parent accompanies your child
New Patients

Bring these forms for your first appointment:

Hematology Department Form
Returning Patients
Forms & Resources
Hematology Department Form
Returning Patient Forms
Resources for Patients & Families
Support Service for Overnight Stays
Cancer Information for Families

When your child has sickle cell disease and needs follow-up care or other basic services, it’s reassuring to know that you can find the same high quality care and services close to home at Nemours duPont Pediatrics, Milford.

A member of our sickle cell disease program at Nemours/Alfred I. duPont Hospital for Children in Wilmington, is available to see your child for routine clinic visits, basic lab work, and help managing sickle cell anemia symptoms.

Nemours Center for Cancer and Blood Disorders at Nemours (NCCBD)

If your child needs comprehensive sickle cell anemia treatment and care, our experienced specialists at Nemours Center for Cancer and Blood Disorders (NCCBD), located at Nemours/ duPont Hospital for Children will care for your child with all the latest advancements and treatments.  

This new Center combines all of our services and treatments for children with cancer or blood disorders, and allows our experts to collaborate and share important research with other experts throughout all Nemours locations.

What is Sickle Cell Disease?

Sickle cell disease is a genetically inherited blood disorder that occurs when a child inherits an altered hemoglobin gene from both parents which causes their red blood cells to take on an abnormal (sickle) shape rather than the normal, smooth disc shape. These abnormally shaped cells clog small blood vessels in your child’s body, impairing blood flow and resulting in pain and organ damage.

Diagnosing Children With Sickle Cell Disease

Delaware, like most states, requires newborn screening — a simple blood test — for sickle cell disease. If your child’s screening test suggests a diagnosis of sickle cell, our pediatric hematology specialists in our Sickle Cell Program, will begin the process of caring for your child.

At Nemours, our experts will:
  • confirm the results of your newborn’s screening with an additional hemoglobin electrophoresis blood test
  • provide extensive education and information about managing sickle cell anemia symptoms and caring for your child
  • initiate important preventive strategies with can protect your child from serious complications
Caring For Children With Sickle Cell Disease
In addition to initial hematology/newborn screening follow-up services, our sickle cell disease team at Nemours/Alfred  I. duPont Hospital for Children in Wilmington, provides:
  • Sickle cell disease preventive care: well-child hematology visits, and sickle cell disease education for you and your child
  • Hydroxyurea therapy
  • Routine diagnostic testing such as TCD: a yearly noninvasive ultrasound used to measure blood flow in children beginning at age 2 through 14 with sickle cell disease to assess the risk of stroke
  • Treatment of sickle cell anemia symptoms and related complications
    • Outpatient Hematology Office: provides well and sick visits and a weekly clinic for children and families
    • Outpatient Hematology Day Therapy Infusion Room: offers a wide-range of blood transfusion services, and pain management services
  • Emergency Department services: 24-hour coverage including phone access to one of our pediatric hematologists
  • Inpatient Hematology/Oncology Unit: a specialized inpatient unit staffed by a team of specialists experienced in caring for children with sickle cell disease
  • Behavioral health care: provides outpatient and inpatient consultation services, psychotherapy services, and neuropsychological evaluations
  • Social work services
  • Access to other Nemours specialists 
    • Combined orthopedic/hematology outpatient office
    • Combined pulmonary/hematology outpatient office
  • Transition to adult hematology care program
  • Sickle Cell Disease School Outreach program
  • Bone Marrow Transplantation program