Mary M. Lee, MD, FAAP

Executive Vice President
Enterprise Chief Scientific Officer
Physician-in-Chief, Delaware Valley

Dr. Mary M. Lee, Enterprise Vice President and Physician-in-Chief for Nemours Delaware Valley Operations

Mary M. Lee, MD, FAAP is a professor of pediatrics at Sidney Kimmel Medical College at Thomas Jefferson University. She also serves as enterprise Chief Scientific Officer and executive vice president for Nemours Children’s Health System, and Physician-in-Chief for Delaware Valley operations, including Nemours Children’s Hospital, Delaware. 

Dr. Lee earned her artium baccalaureus (AB) from Harvard University, and her MD from the University at Buffalo-SUNY (Jacobs) School of Medicine, where she also completed her pediatric residency training. After her clinical fellowship in pediatric endocrinology and diabetes at the Children’s Hospital of Philadelphia, she was a research fellow in developmental reproductive biology at Massachusetts General Hospital (MGH). Upon completion, she accepted a faculty position at MGH in pediatric endocrinology.

Dr. Lee helped clone the receptor for anti-Mullerian hormone (AMH) and elucidated the role of AMH in the testis and in the sexual differentiation gene cascade.  She published seminal studies on the use of the AMH/MIS assay in the diagnostic evaluation of children with cryptorchidism and genital ambiguity, and as a tumor marker in women with ovarian tumors. Her interest in normal and abnormal puberty and reproductive development led to her environmental epidemiology studies to understand the effects of endocrine disruptors and other environmental chemicals on male growth and pubertal development.

Dr. Lee’s research program has been funded by the Environmental Protection Agency, National Institute of Child Health and Human Development (NICHD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute of Environmental Health Sciences (NIEHS), the Charles Hood Medical Foundation, as well as the March of Dimes. 

Dr. Lee was a former president of the Pediatric Endocrine Society and the American Society of Andrology, and she has served on several National Institutes of Health study sections and on the Scientific Advisory council for NIEHS.