Zhengyu Ma, PhD

Research Scientist

Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803

Medical/Dental School

  • MS - Chinese Academy of Medical Sciences & Peking Union Medical College, Biochemistry
  • PhD - University of Pennsylvania, Immunology, 2016
  • MBBS - Qingdao University Medical College, Laboratory Medicine

  • The Nemours Foundation, assignee. Adoptive T-cell therapy using EMPD-specific chimeric antigen receptors for treating IgE-mediated allergic diseases; Unknown Source; (2022).

  • Targeting IgE-producing blood cancers using EMPD-specific chimeric antigen receptor T cells; Regular and Young Investigator Award Abstracts; (2022).

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  • Directing T cell alloreactivity against solid tumors through tumor antigen dependent TCR expression; The Journal of Immunology; (2022).

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  • Tumor-activated alloreactive and xenoreactive T cells and their use in immunotherapy against cancer. USA patent application ; Unknown Source; (2020).

  • The Nemours Foundation, assignee. Adoptive T-cell therapy using FcεRI-based chimeric antigen receptors for treating IgE-mediated allergic diseases. ; Unknown Source; (2019).

  • Chimeric Antigen Receptors Based on Low Affinity Mutants of FcεRI Re-direct T Cell Specificity to Cells Expressing Membrane IgE; Frontiers in Immunology; (2018).

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  • Chimeric antigen receptors based on low affinity mutants of FcεRI re-direct T cell specificity to cells expressing membrane IgE (HYP5P.321); The Journal of Immunology; (2015).

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  • REDD1 Is Essential for Optimal T Cell Proliferation and Survival; PLOS ONE; (2015).

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  • The impact of Nucleofection® on the activation state of primary human CD4 T cells; Journal of Immunological Methods; (2014).

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  • TCR Triggering by pMHC Ligands Tethered on Surfaces via Poly(Ethylene Glycol) Depends on Polymer Length; PLoS ONE; (2014).

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  • Strength of PD-1 signaling differentially affects T-cell effector functions; Proceedings of the National Academy of Sciences; (2013).

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  • Mechanical Force in T Cell Receptor Signal Initiation; Frontiers in Immunology; (2012).

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  • Improved method of preparation of supported planar lipid bilayers as artificial membranes for antigen presentation; Microscopy Research and Technique; (2011).

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  • T cell receptor triggering by force; Trends in Immunology; (2010).

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  • Surface-Anchored Monomeric Agonist pMHCs Alone Trigger TCR with High Sensitivity; PLoS Biology; (2008).

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  • The receptor deformation model of TCR triggering; The FASEB Journal; (2008).

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  • Complement Receptor 3 Ligation of Dendritic Cells Suppresses Their Stimulatory Capacity; The Journal of Immunology; (2007).

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  • Effective gene suppression using small interfering RNA in hard-to-transfect human T cells; Journal of Immunological Methods; (2006).

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  • Ligation of CD28 by Its Natural Ligand CD86 in the Absence of TCR Stimulation Induces Lipid Raft Polarization in Human CD4 T Cells; The Journal of Immunology; (2005).

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  • Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein; Blood; (2001).

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