Matthew D. Di Guglielmo, MD, PhD

Division Chief

Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803

Internship Residency

  • Pediatrics - Nemours/Alfred I. duPont Hospital for Children, 2007

Medical/Dental School

  • MD/PhD - Jefferson Medical College, 2004

Board Certifications

  • American Board of Pediatrics/General Pediatrics

  • The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity; Pediatric Gastroenterology, Hepatology & Nutrition; (2021).

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  • Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity; Pediatric and Developmental Pathology; (2018).

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  • A Pilot Study Measuring The Novel Satiety Hormone, Pro-Uroguanylin, In Adolescents With And Without Obesity; Journal of Pediatric Gastroenterology and Nutrition; (2017).

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  • General Pediatrician-Staffed Behavioral/Developmental Access Clinic Decreases Time to Evaluation of Early Childhood Developmental Disorders; Journal of Developmental and Behavioral Pediatrics; (2017).

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  • Pediatrician preferences, local resources, and economic factors influence referral to a subspecialty access clinic; Primary Health Care Research and Development; (2016).

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  • Female Adolescent Presenting With Abdominal Pain: Accidental Wire Bristle Ingestion Leading to Colonic Perforation; Pediatric Emergency Care; (2015).

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  • A new model to decrease time-to-appointment wait for gastroenterology evaluation; Pediatrics; (2013).

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  • Aortic pseudoaneurysm in a child with a left mainstem bronchial stent; Pediatric Critical Care Medicine; (2008).

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  • Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C; FEBS Letters; (2001).

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  • Guanylyl cyclase C (GC-C) inhibits human colon carcinoma cell growth; Clinical Pharmacology and Therapeutics; (2001).

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  • Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells; Proceedings of the National Academy of Sciences of the United States of America; (2001).

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