Offered by: Nemours
Location: Delaware Valley
Neural Correlates of the Y Chromosome in Autism: XYY Syndrome as a Genetic Model
What is the trial about?
We want to learn more about brain structure and function in boys. Three different conditions that affect boys will be studied: XYY syndrome, Klinefelter syndrome and autism spectrum disorder. Typically developing boys will also be included.
Who can participate?
Boys between the ages of 2 and 17 years old including boys with 47,XYY, boys with autism spectrum disorder and typically developing boys.
What is involved?
Your son will undergo a complete history and physical examination as well as a learning evaluation. This age-appropriate cognitive and behavioral evaluation assesses a number of areas of your child’s cognitive functioning. Some of these observational/interview tests will be videotaped for scoring. A report summarizing these results will be made available to you and/or to the child's teacher if you wish. Your son will also be asked to provide a blood sample, which will be used to assess hormonal development. We will also take photographs to document general appearance. These photographs will be taken of your child with his clothes on. These recorded materials will be used only for research, educational or regulatory purposes. If needed, the procedures will be administered over the course of two days.
There will be one blood draw from the child.
Contact Nemours Clinical Trials
Trial Name: Neural Correlates of the Y Chromosome in Autism: XYY Syndrome as a Genetic Model