CLOVES Syndrome

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CLOVES Syndrome

Expert Help for a Rare Condition


CLOVES syndrome causes tissue overgrowth and vascular anomalies (blood vessels that haven’t developed like they should). It can affect the blood, bones and joints, spine and internal organs, and lymphatic vessels (which carry fluid from the tissue back to the body’s circulation).

CLOVES stands for:

  • Congenital (meaning a child is born with it)
  • Lipomatous (lipomas — slow-growing fatty lumps under the skin on one or both sides of the back and belly)
  • Overgrowth (of fatty tissue, which grow much more quickly than others)
  • Vascular malformations (growths of blood vessels that haven’t developed like they should) 
  • Epidermal nevi (skin lesions)
  • Skeletal and spinal problems and/or scoliosis (curved spine or other spinal problem) 

Nemours Children’s Hospital in Orlando is one of the only pediatric hospitals in the United States that’s equipped to treat CLOVES syndrome. We know that kids with CLOVES need complex care. That’s why we have a complete team of specialists working together to come up with the best solutions for your child.

Services We Offer for CLOVES Syndrome

Services We Offer for CLOVES Syndrome


We treat CLOVES syndrome in our Vascular Anomalies Program. Our fellowship-trained pediatric specialists can perform minimally invasive surgery when appropriate. That often means less scarring, less risk of infection and a faster recovery.

Our range of treatment options to help your child may include:

We also have nurse navigators, educators, social workers and certified Child Life specialists to help guide you every step of the way. 

Why Choose Us for CLOVES Syndrome Care

Why Choose Us for CLOVES Syndrome Care


Because CLOVES is so rare, it’s still unknown to many health care providers. At Nemours Children’s Hospital, our interventional radiologist is one of only about 100 specialists in the United States to provide image-guided procedures to treat CLOVES syndrome.

View Dr. Craig Johnson's Profile »

Highlights of Our Care

At our free-standing, pediatrics-only hospital, you can count on:

  • advanced services and care just for kids, with the latest equipment designed especially for children, and doctors from different fields working together to help your child 
  • advocacy to help you access resources in your community
  • care coordination to help you with scheduling appointments, procedures, tests and at-home care
  • collaboration to build your support network with providers and families facing similar challenges
  • communication with your primary care and community providers
  • support to help you throughout your child’s care

As a team, we all work together to help your child with CLOVES syndrome and improve their quality of life.

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At Nemours, we’re actively researching new approaches for childhood disease prevention, diagnosis and treatment.

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Learn more about your child’s medical condition from the experts at Nemours’ KidsHealth.