Research Labs
Research Labs at Nemours Children’s
Research labs at Nemours are where discovery begins. We're decoding disease mechanisms, developing new therapies, and driving clinical innovation.
Our labs across the Delaware Valley, North Florida, and Central Florida, are led by dedicated investigators working in alignment with our systemwide research priorities. Whether based in molecular biology, immunology, neuroscience, or biomedical engineering, our labs play a key role in transforming pediatric care.
Delaware Valley Research Labs
* New research content coming soon.
Biomedical Research, Innovation & Translation in Extracorporeal Life Support (BRITE Lab)
The BRITE Lab advances extracorporeal life support research through innovative device design, safer technologies, and pediatric critical care solutions.
Brain Stimulation for Treatment of Cognition Lab *
Our lab investigates how noninvasive brain stimulation techniques can improve learning and behavior in children with neurological and developmental conditions.
Cancer Modeling Lab *
We develop patient-derived leukemia models to study disease progression, test new treatments, and understand therapy resistance and relapse.
Cancer Stem Cell Lab *
Our team develops targeted therapies for Down syndrome myeloid leukemia by studying disease models and stem cell behavior that drive relapse.
Clinical & Research Immunology Lab
Our lab provides antibody testing for pediatric autoimmune and immunological disorders using advanced methods and rapid, reliable results.
Craniofacial Outcomes Research Lab *
We study speech and resonance disorders related to cleft palate and craniofacial anomalies, using advanced equipment to assess and improve treatment outcomes.
Dynamics in Epilepsy & Cognitive Development Lab
We study how early-life seizures impact brain development, using advanced recording and treatment strategies to support cognitive outcomes in children with epilepsy.
Gait & Motion Analysis Laboratory *
We investigate walking patterns and mobility in children to improve treatments, guide recovery, and understand long-term outcomes into adulthood.
Moseley Informatics Lab *
We develop tools and data platforms that integrate clinical data and biomedical research to support precision medicine and improve pediatric care.
Neonatal Brain Injury Lab
We research birth-related brain injuries in newborns, including HIE, to help protect brain development and improve outcomes.
Noninvasive Pediatric Pulmonary Evaluation Lab
We develop and tests noninvasive tools to assess lung function in children, aiming to improve diagnosis, monitoring, and care for respiratory conditions.
Pediatric Critical Care Mitochondrial Unit
Investigators in our lab study how mitochondrial function affects critically ill children to improve recovery and guide personalized treatments.
Pediatric Engineering Research Lab
We design, build, and evaluate pediatric-focused technologies and medical devices to solve clinical challenges and advance child health.
Pediatric Gastroenterology Clinical Lab
Our team studies diagnostic tools and treatments for intestinal injury, pancreatic dysfunction, gastric reflux-related aspiration, celiac disease, and IBD.
Pediatric Molecular Diagnostic Laboratory
Our lab provides molecular testing for genetic conditions, as well as genotyping for pharmacogenomics, allowing personalized drug choice and dosing.
Pediatric Muscle Enzyme Histochemistry Lab
Our lab provides diagnostic muscle enzyme histochemistry services, analyzing muscle tissue to aid in the diagnosis of neuromuscular conditions in children.
Pediatric Skeletal Dysplasia Lab
Our lab is developing innovative gene therapies and treatments for rare skeletal disorders, specializing in Morquio A syndrome and other inherited conditions.
Pediatric Speech Research Laboratory
Researchers in our lab develop advanced speech technology to improve diagnosis, treatment, and correction of pediatric communication disorders.
Pediatric T Cell Immunology & Immunotherapy Lab
Our lab develops CAR-T cell therapies and identifies new immune targets to advance treatment for pediatric cancers and immune disorders.
Pediatric Tissue Engineering & Regenerative Medicine Lab
We combine engineering and medicine to create innovative solutions for children with cerebral palsy and heart conditions, improving diagnosis and surgical care.
Pediatric Translational Neuroimaging Lab
Our lab develops PET imaging agents to better detect pediatric neurological diseases and cancers, supporting diagnosis and treatment planning.
Pediatric Transplant Diagnostic & Research Lab
Our Transplant Molecular Diagnostics Laboratory performs pediatric laboratory and clinical laboratory services for pediatric transplant patients.
Perinatal & Pulmonary Translational Research Lab *
Investigators in our lab study how perinatal factors influence lifelong respiratory health, with a focus on improving care for vulnerable infants.
Translational Neurobiology & Drug Discovery Lab
We study how brain cells grow and connect to understand the causes of pediatric brain tumors and neurodevelopmental disorders, and to develop more targeted therapies.
Translational Rheumatology Research Lab
We study how juvenile idiopathic arthritis develops and use advanced tools to predict disease progression, supporting earlier, more effective treatment for better long-term outcomes.
Central Florida Research Labs
* New research content coming soon.
Congenital Cardiac Research Lab *
We study how genetic and epigenetic factors contribute to congenital heart disease to identify new prevention strategies and treatment targets.
Neonatal Immunology & Disease Research Lab *
Our team investigates intestinal inflammation in newborns, exploring how mother’s milk and other factors impact gut health and immune response.
Pediatric 3D Printing & Advanced Image Post-Processing Lab
We create 3D models from CT and MRI scans to help care teams better understand anatomy, plan complex surgeries, and support family communication.
Pediatric Plastic & Reconstructive Surgery Lab
Our team is innovating pediatric surgery research through clinical research, advanced technology, and outcomes analysis to transform children’s lives.
Pediatric Tumor Research Lab
We develop new treatments for challenging childhood cancers, including viral therapies that target tumors while sparing healthy cells for better outcomes.
Pediatric Urology Research Lab *
Our lab uses research models to better understand how specific congenital defects lead to abnormal development of urinary tract and genitals.
Pediatric Wound Healing Research Lab
Our team pioneers treatments for pediatric wound conditions, focusing on excessive scarring and pilonidal disease to improve children's healing outcomes.
Virology Research Lab *
We study how human papillomaviruses and Zika viruses interact with the body, with a focus on their roles in pediatric cancers and other diseases.
