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Translational Rheumatology Lab

Nemours Biomedical Research, Delaware

About Translational Rheumatology Lab

Under the direction of AnneMarie Brescia, MD, the Translational Rheumatology Lab focuses on research activities that can directly lead to new and effective treatment options for children with Juvenile Idiopathic Arthritis (JIA, formerly known as Juvenile Rheumatoid Arthritis) as well as Lyme arthritis.

The lab is part of the Center for Applied Clinical Genomics at Nemours/Alfred I. duPont Hospital for Children in Wilmington, DE. Our work has led to a number of publications and patents.

Principal Investigator
AnneMarie Brescia, MD, FAAP, FACR

Pediatric Rheumatologist
Assistant Professor of Pediatrics, Jefferson Medical College
Program Director, Fellowship Training in Pediatric Rheumatology

Current Research Group
  • AnneMarie Brescia, MD, Principal Investigator
  • Megan Simonds, BA

Research Interests & Projects

Our current research efforts seek to:
  • Discover novel biomarkers for prognosis of Juvenile Idiopathic Arthritis
  • Elucidate signaling pathways that are dysregulated and contribute to the pathogenesis of Juvenile Idiopathic Arthritis
  • Characterize fibroblast-like synoviocytes (FLS) cultured from human synovial fluid to determine what role FLS play in the pathogenesis of Juvenile Idiopathic Arthritis
  • Characterize FLS from acute and chronic Lyme arthritis

Contact Translational Rheumatology Research Laboratory

AnneMarie Brescia, MD, FAAP, FACR

Principal Investigator
Phone: (302) 651-5970
Fax: (302) 651-5942
annemarie.brescia@nemours.org

Location:

Nemours/Alfred I. duPont Hospital for Children
1600 Rockland Road
Wilmington, DE 19803


Applied Clinical Genomics

Our Center for Applied Clinical Genomics works to turn new genetic information discovered by our researchers into tangible improvements in patient care.
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Clinical Trials

Browse our comprehensive list of clinical trials currently underway at Nemours facilities in Delaware and Florida.
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