With Interrupted Aortic Arch, the aorta is not fully developed and is separated into two, unconnected parts where a single arch would normally be formed. This malformation prevents normal blood flow through the aorta and obstructs blood flow to the lower body.
This defect is often accompanied by a VSD. Oxygenated blood flows across the VSD to the right ventricle, where it mixes with de-oxygenated and is pumped through the pulmonary artery to the lungs. Initially some of this mixed blood travels to the lower body through a PDA, shortly after birth this PDA begins to close, thus decreasing circulation to the lower body. Surgical intervention is required to remedy this defect.
