Xuyi Yue
Research Scientist- Radiochemistry, Organic Chemistry, Nuclear Medicine, Molecular Imaging
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Radiotracers for Molecular Imaging of Angiotensin-Converting Enzyme 2; International Journal of Molecular Sciences; (2024).
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PET Imaging of Neurofibromatosis Type 1 with a Fluorine-18 Labeled Tryptophan Radiotracer; Pharmaceuticals; (2024).
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Abusive Head Trauma Animal Models: Focus on Biomarkers; International Journal of Molecular Sciences; (2023).
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PET imaging of brain glymphatic-lymphatic system by targeting VEGFR3; Unknown Source; (2023).
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Special Issue “In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research”; Pharmaceuticals; (2023).
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Unravelling neuroinflammation in abusive head trauma with radiotracer imaging; Pediatric Radiology; (2021).
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Birth-related subdural hemorrhage: prevalence and imaging morphology; Pediatric Radiology; (2021).
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Radiosynthesis of 1-(2-[18f]fluoroethyl)-l-tryptophan using a one-pot, two-step protocol; Journal of Visualized Experiments; (2021).
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Automated production of 1-(2-[<sup>18</sup>F]fluoroethyl)-L-tryptophan for imaging of tryptophan metabolism; Applied Radiation and Isotopes; (2020).
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PET imaging of medulloblastoma with an <sup>18</sup>F-labeled tryptophan analogue in a transgenic mouse model; Scientific Reports; (2020).
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Automated production of a N-methyl-D-aspartate receptor radioligand [ <sup>18</sup> F]GE179 for clinical use; Applied Radiation and Isotopes; (2019).
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Enzymatic activity of palmitoyl-protein thioesterase-1 in serum from schizophrenia significantly associates with schizophrenia diagnosis scales; Journal of Cellular and Molecular Medicine; (2019).
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In Vivo Characterization of Two <sup>18</sup> F-Labeled PDE10A PET Radioligands in Nonhuman Primate Brains; ACS Chemical Neuroscience; (2018).
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Upregulated Sphingosine 1-Phosphate Receptor 1 Expression in Human and Murine Atherosclerotic Plaques; Molecular Imaging and Biology; (2018).
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Synthesis and in vitro characterization of a P2X7 radioligand [<sup>123</sup>I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease; European Journal of Pharmacology; (2018).
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Kinetic modeling of [ <sup>18</sup> F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non-human primate brain; Journal of Neurochemistry; (2018).
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Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter; Bioorganic and Medicinal Chemistry Letters; (2018).
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Design and synthesis of pyrazolopyridine derivatives as sphingosine 1-phosphate receptor 2 ligands; Bioorganic and Medicinal Chemistry Letters; (2018).
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Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation; Bioorganic and Medicinal Chemistry Letters; (2018).
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Cholinergic imbalance in lumbar spinal cord of a rat model of multiple sclerosis; Journal of Neuroimmunology; (2018).
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Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate; Org. Biomol. Chem.; (2017).
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PET study of sphingosine-1-phosphate receptor 1 expression in response to vascular inflammation in a rat model of carotid injury; Molecular Imaging; (2017).
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Chiral resolution of serial potent and selective σ<sub>1</sub>ligands and biological evaluation of (−)-[<sup>18</sup>F]TZ3108 in rodent and the nonhuman primate brain; Bioorganic and Medicinal Chemistry; (2017).
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Automated production of [<sup>18</sup>F]VAT suitable for clinical PET study of vesicular acetylcholine transporter; Applied Radiation and Isotopes; (2016).
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Comparison of [<sup>11</sup>C]TZ1964B and [<sup>18</sup>F]MNI659 for PET imaging brain PDE10A in nonhuman primates; Pharmacology Research and Perspectives; (2016).
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Design, Synthesis, and in Vitro and in Vivo Evaluation of an <sup>18</sup>F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P<sub>1</sub>) PET Tracer; Journal of Medicinal Chemistry; (2016).
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Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates; Nuclear Medicine and Biology; (2016).
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PET Imaging Study of S1PR1 Expression in a Rat Model of Multiple Sclerosis; Molecular Imaging and Biology; (2016).
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A potent and selective C-11 labeled PET tracer for imaging sphingosine-1-phosphate receptor 2 in the CNS demonstrates sexually dimorphic expression; Organic and Biomolecular Chemistry; (2015).
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Lack of neuroinflammation in the HIV-1 transgenic rat: An [<sup>18</sup>F]-DPA714 PET imaging study; Journal of Neuroinflammation; (2015).
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Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subject; NeuroImage; (2015).
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Radiation dosimetry of [<sup>18</sup>F]VAT in nonhuman primates; EJNMMI Research; (2015).
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Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter; Bioorganic and Medicinal Chemistry; (2015).
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A symmetrical fluorous dendron-cyanine dye-conjugated bimodal nanoprobe for quantitative <sup>19</sup>f MRI and NIR fluorescence bioimaging; Advanced Healthcare Materials; (2014).
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Dye-Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy; Advanced Materials; (2014).
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One-pot two-step radiosynthesis of a new <sup>18</sup>F-labeled thiol reactive prosthetic group and its conjugate for insulinoma imaging; Molecular Pharmaceutics; (2014).
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Novel <sup>19</sup>F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS; Molecular Pharmaceutics; (2014).
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PET and NIR optical imaging using self-illuminating <sup>64</sup>Cu-doped chelator-free gold nanoclusters; Biomaterials; (2014).
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PET imaging of neuroinflammation in a rat traumatic brain injury model with radiolabeled TSPO ligand DPA-714; European Journal of Nuclear Medicine and Molecular Imaging; (2014).
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Photosensitizer loaded nano-graphene for multimodality imaging guided tumor photodynamic therapy; Theranostics; (2014).
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[<sup>18</sup>F]DPA-714 PET imaging of AMD3100 treatment in a mouse model of stroke; Molecular Pharmaceutics; (2014).
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Longitudinal PET imaging of muscular inflammation using <sup>18</sup>F-DPA-714 and <sup>18</sup>F-alfatide II and differentiation with tumors; Theranostics; (2014).
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Dual-factor triggered fluorogenic nanoprobe for ultrahigh contrast and subdiffraction fluorescence imaging; Biomaterials; (2013).
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Development of a new thiol site-specific prosthetic group and its conjugation with [Cys<sup>40</sup>]-exendin-4 for in vivo targeting of insulinomas; Bioconjugate Chemistry; (2013).
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PH-sensitive fluorescent dyes: Are they really ph-sensitive in cells?; Molecular Pharmaceutics; (2013).
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Photosensitizer-conjugated silica-coated gold nanoclusters for fluorescence imaging-guided photodynamic therapy; Biomaterials; (2013).
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Synthesis and characterization of fluorinated conjugates of albumin; Journal of Fluorine Chemistry; (2013).
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Avoiding steric congestion in dendrimer growth through proportionate branching: A twist on da Vincis rule of tree branching; Journal of Organic Chemistry; (2012).
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Fluorine-Containing Chiral Drugs; Chiral Drugs: Chemistry and Biological Action; (2011).
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A practical approach to synthesize the C(9)-C(24) fragment of (+)-discodermolide; Chinese Journal of Chemistry; (2010).
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Cu(II)-mediated methylthiolation of aryl C-H bonds with DMSO; Organic Letters; (2010).
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Total synthesis of gem-difluoromethylenated analogues of pironetin; Synthesis; (2010).
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Palladium-catalyzed cross-coupling of ethyl α-bromo-α- fluoroacetate with arylboronic acids: Facile synthesis of α-aryl-α- fluoroacetate; Synthesis; (2010).
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Highly diastereoselective zn/sncl<sub>2</sub>-mediated gem- difluoroallylation of chiral hydrazones; Organic Letters; (2009).
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Metal-mediated gem-difluoroallylation of N-acylhydrazones: Highly efficient synthesis of α,α-difluorohomoallylic amines; Chinese Journal of Chemistry; (2009).
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Synthesis of 2′,3′-dideoxy-6′,6′-difluoro-3′-azanucleosides; Journal of Fluorine Chemistry; (2008).
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Synthesis of gem-difluoromethylenated goniodiol; Chinese Journal of Organic Chemistry; (2008).
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Synthesis of a series of novel 2′,3′-dideoxy-6′,6′-difluoro-3′-thionucleosides; Tetrahedron; (2007).
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