Kathryn Blake, PharmD

Opportunities for Pharmacogenomics in Pediatrics: Prescribing Trends of Psychiatric Medications With Pharmacogenomic Implications at a Multistate Pediatric Health System; Journal of Pediatric Pharmacology and Therapeutics; (2025).

Drivers of Bronchodilator Use in Bronchiolitis: Analyzing Treatment Trends From Pediatric Emergency Department Practices; Pediatric Emergency Care; (2025).

Early Administration of Steroids in the Ambulance Setting: An Observational Design Trial (EASI-AS-ODT); Academic Emergency Medicine; (2024).

Changes in Bronchiolitis Characteristics During the COVID-19 Pandemic: A Description of Pediatric Emergency Department Visits in a Community Hospital, 2019-2021; Clinical Pediatrics; (2024).

Association of Sputum Eosinophilia With Easily Measured Type-2 Inflammatory Biomarkers in Untreated Mild Persistent Asthma; Journal of Allergy and Clinical Immunology in Practice; (2024).

A Community-Guided Approach to Bronchiolitis: A Needs Assessment and Illness Perception Study; Journal of Patient Experience; (2024).

Rationale and design for a pragmatic randomized trial to assess gene-based prescribing for SSRIs in the treatment of depression; Clinical and Translational Science; (2024).

Evaluation of the implementation of evidence-based pediatric asthma exacerbation treatments in a regional consortium of emergency medical Services Agencies; Journal of Asthma; (2024).

Lack of awareness and knowledge of NHLBI 2020 Asthma Focused Updates; Journal of Allergy and Clinical Immunology in Practice; (2024).

Nationwide trends in hospitalization, medical costs, and mortality for asthma after introduction of biologics: A cross-sectional study in the United States; Journal of Managed Care and Specialty Pharmacy; (2023).

Ethics Challenges in Pediatric Research; Journal of Pediatric Pharmacology and Therapeutics; (2023).

Comprehension by Caregivers and Adolescents of Clinical Trial Information Delivered via Multimedia Video Versus Conventional Practice: Nonrandomized Controlled Trial; Jmir Pediatrics and Parenting; (2023).

Comparison of variants in TPMT and NUDT15 between sequencing and genotyping methods in a multistate pediatric institution; Clinical and Translational Science; (2023).

Beginning to Address an Implementation Gap in Asthma: Clinicians' Views of Prescribing Reliever Budesonide-Formoterol Inhalers and SMART in the United States; Journal of Allergy and Clinical Immunology in Practice; (2023).

A digital health application for managing pediatric asthma: Use and benefits; Informatics for Health and Social Care; (2023).

A Call for the United States to Accelerate the Implementation of Reliever Combination Inhaled Corticosteroid-Formoterol Inhalers in Asthma; American Journal of Respiratory and Critical Care Medicine; (2023).

Best–worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy; Implementation Science Communications; (2022).

“It is kind of like a responsibility thing”: transitional challenges in asthma medication adherence among adolescents and young adults; Journal of Asthma; (2022).

Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy; Clinical and Translational Science; (2022).

Comprehension by Caregivers and Adolescents of Clinical Trial Information Delivered via Multimedia Video Versus Conventional Practice: Nonrandomized Controlled Trial (Preprint); Unknown Source; (2022).

Biomarkers to Predict Response to Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists in Adolescents and Adults with Mild Persistent Asthma; Annals of the American Thoracic Society; (2022).

Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators; Clinical and Translational Science; (2022).

The challenge of addressing obesity in people with poorly controlled asthma; Obesity Science and Practice; (2021).

The 2020 focused updates to the NIH asthma management guidelines: Key points for pediatricians; Pediatrics; (2021).

Telemedicine and adherence monitoring in children with asthma; Current Opinion in Pulmonary Medicine; (2021).

Single Nucleotide Polymorphisms (SNPs) in PRKG1 & SPATA13 -AS1 are associated with bronchodilator response: A pilot study during acute asthma exacerbations in African American children; Pharmacogenetics and Genomics; (2021).

Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma; Lancet Child and Adolescent Health; (2021).

Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems; Clinical Pharmacology and Therapeutics; (2021).

Key Considerations for Selecting a Genomic Decision Support Platform for Implementing Pharmacogenomics; Clinical Pharmacology and Therapeutics; (2021).

Health-related quality of life and health utilities of mild, moderate, and severe asthma: Evidence from the medical expenditure panel survey; Journal of Asthma and Allergy; (2021).

Geography, generalisability, and susceptibility in clinical trials; Lancet Respiratory Medicine; (2021).

Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network; Genetics in Medicine; (2021).

Ensuring access to albuterol in schools: From policy to implementation an official ATS/AANMA/ALA/NASN policy statement; American Journal of Respiratory and Critical Care Medicine; (2021).

Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network (Genetics in Medicine, (2019), 21, 3, (743-747), 10.1038/s41436-018-0080-y); Genetics in Medicine; (2021).

A Single Inhaler Combining a Corticosteroid and Long-Acting Beta-2 Agonist for Maintenance with Additional Doses for Reliever Therapy (SMART): Obstacles for Asthma Patients in the USA; Pediatric Allergy Immunology and Pulmonology; (2021).

Biomarkers of Type 2 Airway Inflammation as Predictors of Loss of Asthma Control During Step-Down Therapy for Well-Controlled Disease: The Long-Acting Beta-Agonist Step-Down Study (LASST); Journal of Allergy and Clinical Immunology in Practice; (2020).

2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group; Journal of Allergy and Clinical Immunology; (2020).

Considerations for the Child with Nonatopic Asthma; Pediatric Allergy Immunology and Pulmonology; (2020).

Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients; JAMA Network Open; (2020).

Methods and implementation of a pediatric asthma pharmacogenomic study in the emergency department setting; Pharmacogenetics and Genomics; (2020).

Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network (Genetics in Medicine, (2019), 21, 3, (743-747), 10.1038/s41436-018-0080-y); Genetics in Medicine; (2020).

Early administration of steroids in the ambulance setting: Protocol for a type I hybrid effectiveness-implementation trial with a stepped wedge design; Contemporary Clinical Trials; (2020).

Knowledge and attitudes on pharmacogenetics among pediatricians; Journal of Human Genetics; (2020).

Medical costs and productivity loss due to mild, moderate, and severe asthma in the United States; Journal of Asthma and Allergy; (2020).

Step-up therapy in black children and adults with poorly controlled asthma; New England Journal of Medicine; (2019).

Postoperative Pain and 14-Day Recovery in Children Undergoing Adenotonsillectomy: Low Thermal Damage Device Versus Electrosurgery; Ear Nose and Throat Journal; (2019).

Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation; Journal of Allergy and Clinical Immunology in Practice; (2019).

Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network; Genetics in Medicine; (2019).

Novel Implementation of Genotype-Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial; Clinical and Translational Science; (2019).

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing; Genetics in Medicine; (2019).

Mometasone or tiotropium in mild asthma with a low sputum eosinophil level; New England Journal of Medicine; (2019).

Genotype tailored treatment of mild symptomatic acid reflux in children with uncontrolled asthma (GenARA): Rationale and methods; Contemporary Clinical Trials; (2019).

Emergency Medical Services Administration of Systemic Corticosteroids for Pediatric Asthma: A Statewide Study of Emergency Department Outcomes; Academic Emergency Medicine; (2019).

Asthma: moving toward a global children's charter; Lancet Respiratory Medicine; (2019).

Asthma Guidelines Priority Topics: Intermittent Inhaled Corticosteroid Therapy and Inhaled Corticosteroids with Long Acting Beta-Agonists as Reliever Therapy; Pediatric Allergy Immunology and Pulmonology; (2019).

Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era; Contemporary Clinical Trials; (2019).

Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network (Genetics in Medicine, (2019), 21, 3, (743-747), 10.1038/s41436-018-0080-y); Genetics in Medicine; (2019).

Association of inhaled corticosteroids and long-acting muscarinic antagonists with asthma control in patients with uncontrolled, persistent asthma a systematic review and meta-analysis; JAMA Journal of the American Medical Association; (2018).

Association of inhaled corticosteroids and long-acting β-agonists as controller and quick relief therapy with exacerbations and symptom control in persistent asthma a systematic review and meta-analysis; JAMA Journal of the American Medical Association; (2018).

Temporary increased dose of inhaled corticosteroids in yellow zone, does it work?; Pediatric Allergy Immunology and Pulmonology; (2018).

Step-Down Therapy for Asthma Well Controlled on Inhaled Corticosteroid and Long-Acting Beta-Agonist: A Randomized Clinical Trial; Journal of Allergy and Clinical Immunology in Practice; (2018).

Quintupling inhaled glucocorticoids to prevent childhood asthma exacerbations; New England Journal of Medicine; (2018).

Improving the affordability of prescription medications for people with chronic respiratory disease an official American thoracic society policy statement; American Journal of Respiratory and Critical Care Medicine; (2018).

Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?; Journal of Allergy and Clinical Immunology; (2018).

Asthma Guidelines from the National Asthma Education and Prevention Program: Where Are We Now?; Pediatric Allergy Immunology and Pulmonology; (2018).

Asthma Guidelines Priority Topic: Long-Acting Anti-Muscarinic Agents in Asthma Management as Add-On to Inhaled Corticosteroids; Pediatric Allergy Immunology and Pulmonology; (2018).

A cognitive approach for design of a multimedia informed consent video and website in pediatric research; Journal of Biomedical Informatics; (2017).

The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting; Clinical and Translational Science; (2017).

Personalized Medicine in Preschool Children with Asthma; Pediatric Allergy Immunology and Pulmonology; (2017).

Inhaling Essential Oils: Purported Benefits and Harms; Pediatric Allergy Immunology and Pulmonology; (2017).

Acetaminophen and Asthma in Children: Association or Causality?; Pediatric Allergy Immunology and Pulmonology; (2017).

Improving adherence to asthma medications: Current knowledge and future perspectives; Current Opinion in Pulmonary Medicine; (2017).

Macrolides for Acute Wheezing Episodes in Preschool Children; Pediatric Allergy Immunology and Pulmonology; (2016).

Individualized therapy for persistent asthma in young children; Journal of Allergy and Clinical Immunology; (2016).

Acetaminophen versus Ibuprofen in young children with Mild Persistent Asthma; New England Journal of Medicine; (2016).

Mepolizumab: A New Class of Treatment for Adolescents with Severe Persistent Asthma; Pediatric Allergy Immunology and Pulmonology; (2016).

Management of Acute Cough in Children: Where Do We Go from Here?; Pediatric Allergy Immunology and Pulmonology; (2016).

Adolescent Asthma Pharmacotherapy in a State of Flux; Pediatric Allergy Immunology and Pulmonology; (2015).

Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial; JAMA Journal of the American Medical Association; (2015).

Vitamin D and Asthma: Association, Causality, or Intervention?; Pediatric Allergy Immunology and Pulmonology; (2015).

Use of mobile devices and the internet for multimedia informed consent delivery and data entry in a pediatric asthma trial: Study design and rationale; Contemporary Clinical Trials; (2015).

Updated Guidelines on Allergic Rhinitis - Anything New?; Pediatric Allergy Immunology and Pulmonology; (2015).

Pharmacogenomics of long-acting β2-agonists; Expert Opinion on Drug Metabolism and Toxicology; (2015).

Nonprescription epinephrine metered-dose inhaler: To be or not to be; Pediatric Allergy Immunology and Pulmonology; (2014).

New and evolving therapies for cystic fibrosis patients; Pediatric Allergy Immunology and Pulmonology; (2014).

Inhaled mannitol for children with cystic fibrosis: Why it missed the mark for FDA approval; Pediatric Allergy Immunology and Pulmonology; (2014).

Considerations for care: Management of asthma in the child with sickle cell disease; Pediatric Allergy Immunology and Pulmonology; (2013).

Chiral switch drugs for asthma and allergies: True benefit or marketing hype; Pediatric Allergy Immunology and Pulmonology; (2013).

A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics; Pharmacogenomics Journal; (2013).

Role of biomarkers in understanding and treating children with asthma: Towards personalized care; Pharmacogenomics and Personalized Medicine; (2013).

Association of CYP2C19 polymorphisms and lansoprazole-associated respiratory adverse effects in children; Journal of Pediatrics; (2013).

Pharmacogenetics of asthma controller treatment; Pharmacogenomics Journal; (2013).

Nutrigenetic response to omega-3 fatty acids in obese asthmatics (NOOA): Rationale and methods; Contemporary Clinical Trials; (2013).

Methacholine PC20 in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16; Pulmonary Pharmacology and Therapeutics; (2013).

Gastroesophageal reflux disease and childhood asthma; Current Opinion in Pulmonary Medicine; (2013).

Small airway targeted therapy in pediatric Asthma: Are we there yet?; Pediatric Allergy Immunology and Pulmonology; (2013).

Principles of Lung Therapeutics; Nursing Care in Pediatric Respiratory Disease; (2013).

Does use of inhaled corticosteroid for management of asthma in children make them shorter adults?; Pediatric Allergy Immunology and Pulmonology; (2013).

Sickle-cell trait and atopic and inflammatory disease in children; Pediatric Allergy Immunology and Pulmonology; (2013).

Bioavailability of inhaled fluticasone propionate via chambers/masks in young children; European Respiratory Journal; (2012).

Treatment of pediatric asthma with proton pump inhibitors: Three strikes, game over; Pediatric Allergy Immunology and Pulmonology; (2012).

Pharmacogenomic testing in the asthma clinic: Will inhaled corticosteroids lead the way?; Pediatric Allergy Immunology and Pulmonology; (2012).

Management of wheezing in preschool children; Pediatric Allergy Immunology and Pulmonology; (2012).

Lansoprazole for children with poorly controlled asthma a randomized controlled trial; JAMA; (2012).

Comparison of inhaled corticosteroids: What you need to know in choosing a product; Pediatric Allergy Immunology and Pulmonology; (2011).

As needed use of inhaled corticosteroids for management of mild persistent asthma in children; Pediatric Allergy Immunology and Pulmonology; (2011).

Asthma in sickle cell disease: Implications for treatment; Anemia; (2011).

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): A multicentre randomised trial; Lancet; (2010).

Pharmacogenetics of asthma; Current Opinion in Pulmonary Medicine; (2009).

Efficacy of esomeprazole for treatment of poorly controlled asthma; New England Journal of Medicine; (2009).

EUR-1008 pancreatic enzyme replacement is safe and effective in patients with cystic fibrosis and pancreatic insufficiency; Journal of Cystic Fibrosis; (2009).

The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: Effectiveness of early intervention with budesonide in mild persistent asthma; Journal of Allergy and Clinical Immunology; (2008).

Population pharmacodynamic model of bronchodilator response to inhaled albuterol in children and adults with asthma; Chest; (2008).

Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma; Chest; (2006).

Efficacy and safety of inhaled fluticasone propionate chlorofluorocarbon in 2- to 4-year-old patients with asthma: Results of a double-blind, placebo-controlled study; Annals of Allergy Asthma and Immunology; (2006).

Reply [4]; Journal of Pediatrics; (2006).

Study of a novel pancreatic enzyme replacement therapy in pancreatic insufficient subjects with cystic fibrosis; Journal of Pediatrics; (2006).

The C523A β2 adrenergic receptor polymorphism associates with markers of asthma severity in African Americans; Journal of Asthma; (2006).

Review of guidelines and the literature in the treatment of acute bronchospasm in asthma; Pharmacotherapy; (2006).

Safety of budesonide inhalation suspension in infants aged six to twelve months with mild to moderate persistent asthma or recurrent wheeze; Journal of Pediatrics; (2005).

Impact of inadequately controlled asthma: A need for targeted therapy?; Journal of Clinical Pharmacy and Therapeutics; (2004).

Fluticasone propionate and salmeterol administered via Diskus compared with salmeterol or fluticasone propionate alone in patients suboptimally controlled with short-acting β2-agonists; Annals of Allergy Asthma and Immunology; (2004).

Effect of Montelukast on Time-Course of Exhaled Nitric Oxide in Asthma: Influence of LTC4 Synthase A-444C Polymorphism; Pediatric Pulmonology; (2003).

Lack of effect of fluticasone propionate aqueous nasal spray on the hypothalamic-pituitary-adrenal axis in 2- and 3-year-old patients; Pediatrics; (2003).

Early intervention with budesonide in mild persistent asthma: A randomised, double-blind trial; Lancet; (2003).

Exhaled nitric oxide concentrations: Online versus offline values in healthy children; Pediatric Pulmonology; (2002).

Effect of β2-agonist treatment and spirometry on exhaled nitric oxide in healthy children and children with asthma; Pediatric Pulmonology; (2002).

Plastic bottles as spacers for a pressurized metered-dose inhaler: In vitro characteristics; West Indian Medical Journal; (2001).

Management of allergic rhinitis and sinusitis; Journal of Pharmacy Practice; (2001).

Introduction: Pulmonary medicine II; Journal of Pharmacy Practice; (2001).

Introduction: Pulmonary medicine; Journal of Pharmacy Practice; (2001).

Drug treatment of airway inflammation in asthma; Pharmacotherapy; (2001).

Drug therapy approaches in the treatment of acute severe asthma in hospitalised children; Paediatric Drugs; (2001).

Exhaled nitric oxide as an indicator of severity of asthmatic inflammation; Pediatric Emergency Care; (2000).

Erratum: Montelukast in asthma management (Annals of Pharmacotherapy (1999) 33 (1299-1314)); Annals of Pharmacotherapy; (2000).

FE(NO): Relationship to exhalation rates and online versus bag collection in healthy adolescents; American Journal of Respiratory and Critical Care Medicine; (2000).

Exhaled nitric oxide measurements in childhood asthma: Techniques and interpretation; Pediatric Pulmonology; (1999).

Montelukast dose selection in 6- to 14-year-olds: Comparison of single-dose pharmacokinetics in children and adults; Journal of Clinical Pharmacology; (1999).

Montelukast: Data from clinical trials in the management of asthma; Annals of Pharmacotherapy; (1999).

Prevention of exercise-induced bronchospasm in pediatric asthma patients: A comparison of salmeterol powder with albuterol; Annals of Allergy Asthma and Immunology; (1999).

Measurement of pulmonary exhaled nitric oxide: Relationship to exhalation rates and inline versus bag collection techniques; Critical Care Medicine; (1998).

Asthma management: What you need to know; American Druggist; (1998).

Manual volume-controlled ventilation in preterm neonates compared to ventilation via self-inflating resuscitator; Respiratory Care; (1996).

Theophylline attenuation of airway responses to allergen: Comparison with cromolyn metered-dose inhaler; Journal of Allergy and Clinical Immunology; (1995).

Reply; Journal of Allergy and Clinical Immunology; (1995).

The Effect of Short‐Term Administration of Theophylline on Erythropoietin Levels in Healthy Adults; Pharmacotherapy the Journal of Human Pharmacology and Drug Therapy; (1994).

Salmeterol: Its place in asthma management; Annals of Pharmacotherapy; (1994).

Bioequivalence of a generic slow-release theophylline tablet in children; Journal of Pediatrics; (1994).

Relative amount of albuterol delivered to lung receptors from a metered- dose inhaler and nebulizer solution; Bioassay by histamine bronchoprovocation; Chest; (1992).

Regularly scheduled versus as-needed use of inhaled β agonists in the treatment of asthma; Clinical Pharmacy; (1992).

Factors affecting clinical response to asthma treatment; Journal of the American Osteopathic Association; (1992).

Evaluation of a generic albuterol metered-dose inhaler: Importance of priming the MDI; Annals of Allergy; (1992).

Relative efficacy of phenytoin and phenobarbital for the prevention of theophylline-induced seizures in mice; Annals of Emergency Medicine; (1988).

Death of a child associated with multiple overdoses of acetaminophen; Clinical Pharmacy; (1988).