William Giles Stuart Mackenzie, MD

Orthopaedic Surgeon

Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803


W.G. Stuart Mackenzie, MD, is a pediatric orthopedic surgeon. He received his undergraduate degree from University of Toronto and a graduate degree from Boston University. He worked for two years in Africa with HIV patients at the Center for Infectious Disease Research in Zambia. Dr. Mackenzie attended New York Medical College and completed his orthopedic surgery residency at Columbia University in New York. He joined the team at Nemours Children’s as a Pediatric Orthopedic Surgery fellow before joining the staff full-time. He has won multiple awards, including Physician of the Year at the Morgan Stanley Children’s Hospital of New York and is the author of multiple journal articles and book chapters on pediatric spine deformity. He is an active member in the Pediatric Orthopedic Society of North America (POSNA) and the American Orthopedic Association (AOA). Dr. Mackenzie’s clinical interests include skeletal dysplasia, scoliosis and spine deformity and trauma. Provides care in Wilmington, Del., and Orlando.


  • Pediatric Orthopedic Surgery - Alfred I. duPont Hospital for Children, 2019


  • Orthopedic Surgery - Columbia University/Presbyterian Hospital, 2018

Medical/Dental School

  • MD - New York Medical College, 2013

Board Certifications

  • American Board of Orthopaedic Surgery

  • Achondroplasia
  • Cervical Instability
  • Hip Deformity
  • Lower Extremity Deformity
  • Morquio Syndrome
  • Orthopedics
  • Pediatric Orthopedics
  • Scoliosis
  • Skeletal Dysplasia

  • Achondroplasia natural history study (CLARITY): 60-year experience in orthopedic surgery from four skeletal dysplasia centers.; Orphanet journal of rare diseases; (2023).

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  • Tracheal Narrowing and Its Impact on Anesthesia Care in Patients With Morquio A (Mucopolysaccharidosis Type IVA): An Observational Study.; Anesthesia and analgesia; (2023).

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  • Predictors of rod length gain and sagittal alignment change after magnetically controlled growing rod lengthening.; Spine; (2023).

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  • Growth Modulation by Tension Band Plate in Achondroplasia With Varus Knee Deformity: Comparison of Gait Analysis Measurements.; Journal of pediatric orthopedics; (2023).

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  • Walking status and spinopelvic parameters in young children with achondroplasia: 10-year follow-up; Spine Deformity; (2023).

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  • Risk Factors for Rebound After Correction of Genu Valgum in Skeletal Dysplasia Patients Treated by Tension Band Plates.; Journal of pediatric orthopedics; (2022).

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  • Elongation-Derotation-Flexion Casting Treatment of Early-Onset Progressive Scoliosis in Skeletal Dysplasia.; Journal of pediatric orthopedics; (2022).

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  • Evaluation of Gait Pattern and Lower Extremity Kinematics of Children with Morquio Syndrome (MPS IV). ; Diagnostics (Basel, Switzerland); (2021).

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  • What Should I Wear to Clinic? A National Survey of Pediatric Orthopaedic Patients and Parents.; Journal of pediatric orthopedics; (2020).

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  • Team Approach: Preventing Surgical Site Infections in Pediatric Scoliosis Surgery.; JBJS reviews; (2018).

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  • Prevalence of scoliosis in patients with Fontan circulation; Archives of Disease in Childhood; (2013).

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  • Surgical site infection following spinal Instrumentation for scoliosis: A multicenter analysis of rates, risk factors, and pathogens; Journal of Bone and Joint Surgery; (2013).

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