Edward B Mougey, PhD
Research Scientist- Eosinophilic Esophagitis
- Pharmacogenomics
- Precision Medicine
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Comparative Effectiveness of Intravenous Azithromycin Versus Erythromycin Stimulating Antroduodenal Motility in Children.; Journal of pediatric gastroenterology and nutrition; (2022).
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Proton Pump Inhibitor Therapy for Eosinophilic Esophagitis: History, Mechanisms, Efficacy, and Future Directions.; Journal of asthma and allergy; (2022).
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Telehealth for Pediatric Gastroenterology Care Now; JPGN Reports; (2022).
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STAT6 Variants Associate With Relapse of Eosinophilic Esophagitis in Patients Receiving Long-term Proton Pump Inhibitor Therapy; Clinical Gastroenterology and Hepatology; (2021).
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Pharmacogenomics fail to explain proton pump inhibitor refractory esophagitis in pediatric esophageal atresia; Neurogastroenterology and Motility; (2021).
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Novel Implementation of Genotype-Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial; Clinical and Translational Science; (2019).
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Genotype tailored treatment of mild symptomatic acid reflux in children with uncontrolled asthma (GenARA): Rationale and methods; Contemporary Clinical Trials; (2019).
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Fish oil supplementation in overweight/obese patients with uncontrolled asthma a randomized trial; Annals of the American Thoracic Society; (2019).
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CYP2C19 and STAT6 Variants Influence the Outcome of Proton Pump Inhibitor Therapy in Pediatric Eosinophilic Esophagitis; Journal of Pediatric Gastroenterology and Nutrition; (2019).
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Association between CYP2C19 extensive metabolizer phenotype and childhood anti-reflux surgery following failed proton pump inhibitor medication treatment; European Journal of Pediatrics; (2018).
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Association Between CYP2C19*17 Alleles and pH Probe Testing Outcomes in Children With Symptomatic Gastroesophageal Reflux; Journal of Clinical Pharmacology; (2018).
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Serum folate concentrations, asthma, atopy, and asthma control in Peruvian children; Respiratory Medicine; (2017).
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The Duffy antigen receptor for chemokines regulates asthma pathophysiology; Clinical and Experimental Allergy; (2017).
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Free 25(OH)D concentrations are associated with atopy and lung function in children with asthma; Annals of Allergy, Asthma and Immunology; (2017).
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Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial; JAMA - Journal of the American Medical Association; (2015).
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25-hydroxy vitamin D levels are associated with childhood asthma in a population-based study in Peru; Clinical and Experimental Allergy; (2015).
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Association between serum 25-hydroxy Vitamin D levels and blood pressure among adolescents in two resource-limited settings in Peru; American Journal of Hypertension; (2015).
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Prevalence and risk factors for allergic rhinitis in two resource-limited settings in Peru with disparate degrees of urbanization; Clinical and Experimental Allergy; (2015).
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Lansoprazole is associated with worsening asthma control in children with the CYP2C19 poor metabolizer phenotype; Annals of the American Thoracic Society; (2015).
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ALOX5 Polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma; Clinical and Experimental Allergy; (2013).
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Association of CYP2C19 polymorphisms and lansoprazole-associated respiratory adverse effects in children; Journal of Pediatrics; (2013).
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Methacholine PC<inf>20</inf> in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16; Pulmonary Pharmacology and Therapeutics; (2013).
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Biologic mechanisms of environmental tobacco smoke in children with poorly controlled asthma: Results from a multicenter clinical trial; Journal of Allergy and Clinical Immunology: In Practice; (2013).
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Nutrigenetic response to omega-3 fatty acids in obese asthmatics (NOOA): Rationale and methods; Contemporary Clinical Trials; (2013).
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Pharmacogenetics of asthma controller treatment; Pharmacogenomics Journal; (2013).
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Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast; Journal of Clinical Pharmacology; (2011).
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Absorption of montelukast is transporter mediated: A common variant of OATP2B1 is associated with reduced plasma concentrations and poor response; Pharmacogenetics and Genomics; (2009).
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Oxandrolone enhances skeletal muscle myosin synthesis and alters global gene expression profile in Duchenne muscular dystrophy; American Journal of Physiology - Endocrinology and Metabolism; (2006).
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Mitochondrial ribosomal proteins: Candidate genes for mitochondrial disease; Genetics in Medicine; (2004).
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Growth factor regulation of human growth plate chondrocyte proliferation in vitro; Biochemical and Biophysical Research Communications; (2004).
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Using real-time, quantitative pcr for rapid genotyping of the steroid 21-hydroxylase gene in a north florida population; Journal of Clinical Endocrinology and Metabolism; (2002).
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Determination of human beta(2)-adrenoceptor haplotypes by denaturation selective amplification and subtractive genotyping; American journal of pharmacogenomics : genomics-related research in drug development and clinical practice; (2001).
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Mammalian mitochondrial ribosomal proteins (4): Amino acid sequencing, characterization, and identification of corresponding gene sequences; Journal of Biological Chemistry; (2000).
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Heart-specific splice-variant of a human mitochondrial ribosomal protein (mRNA processing; tissue specific splicing); Gene; (2000).
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Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences; Journal of Biological Chemistry; (1999).
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Expression of the components of the insulin-like growth factor axis across the growth-plate; Molecular and Cellular Endocrinology; (1999).
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Metazoan rDNA enhancer acts by making more genes transcriptionally active; Journal of Cell Biology; (1996).
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Virtually the entire Xenopus laevis rDNA multikilobase intergenic spacer serves to stimulate polymerase I transcription; Journal of Biological Chemistry; (1996).
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The terminal balls characteristic of eukaryotic rRNA transcription units in chromatin spreads are rRNA processing complexes; Genes and Development; (1993).
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A U3 small nuclear ribonucleoprotein-requiring processing event in the 5′ external transcribed spacer of Xenopus precursor rRNA; Molecular and Cellular Biology; (1993).
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Wheat Germ and Yeast RNA Polymerase II: Photoaffinity Labeling by 4-Thiouracil 5′-Monophosphate Positioned Uniquely at the 3′ End of an Enzyme-Bound [<sup>32</sup>P]-Containing Transcript; Biochemistry; (1993).
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Expression of mouse and frog rRNA genes: transcription and processing; Molecular and Cellular Biochemistry; (1991).
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News from the nucleolus: rRNA gene expression; Trends in Biochemical Sciences; (1991).
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The Xenopus ribosomal DNA 60- and 81-base-pair repeats are position-dependent enhancers that function at the establishment of the preinitiation complex: analysis in vivo and in an enhancer-responsive in vitro system; Molecular and Cellular Biology; (1989).
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Formation and characterization of precise eucaryotic transcription complexes using a semisynthetic DNA template and specific oligoribonucleotide primers; Analytical Biochemistry; (1988).
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