Rodney Scott, MD

Division Chief Neurology

Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803

Internship

  • General Surgery - Harare Central Hospital, 1989
  • Neurosurgery - Harare Central Hospital, 1989
  • Oncology - Parirenyatwa General Hospital, 1989

Residency

  • Pediatric Neurology - Great Ormond Childrens Hospital, 2000

Internship Residency

  • Academic General Pediatrics - Chelsea & Westminster Hospital, 1994

Medical/Dental School

  • Doctor of Philosophy - University College London, 1999
  • MBChB - University of Zimbabwe, 1988

Board Certifications

  • Royal College of Physicians United Kingdom

  • MRI for assessing the impact of febrile status epilepticus and predicting outcomes; Febrile Seizures: New Concepts and Consequences; (2022).

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  • Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures; Neurobiology of Disease; (2022).

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  • Biological networks and complexity in early-onset motor neuron diseases; Frontiers in Neurology; (2022).

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  • Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures; Unknown Source; (2022).

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  • Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions; Communications Biology; (2022).

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  • Seizure outcome determinants in children after surgery for single unilateral lesions on MRI : role of preoperative ictal and interictal EEG; Epilepsia; (2022).

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  • Expedited epilepsy surgery prior to drug resistance in children: a frontier worth crossing?; Brain; (2022).

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  • Mechanisms for Cognitive Impairment in Epilepsy: Moving Beyond Seizures; Frontiers in Neurology; (2022).

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  • The UK experience of stereoelectroencephalography in children: An analysis of factors predicting the identification of a seizure-onset zone and subsequent seizure freedom; Epilepsia; (2021).

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  • The UK experience of stereoelectroencephalography in children: An analysis of factors predicting the identification of a seizure onset zone and subsequent seizure freedom; medRxiv; (2021).

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  • Levetiracetam for treatment of convulsive status epilepticus: Time to update childhood convulsive status epilepticus treatment guidelines?; Archives of Disease in Childhood; (2021).

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  • Gregory L. Holmes; Child Neurology: Its Origins, Founders, Growth and Evolution; (2021).

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  • Fine Spike Timing in Hippocampal-Prefrontal Ensembles Predicts Poor Encoding and Underlies Behavioral Performance in Healthy and Malformed Brains; Cerebral Cortex; (2021).

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  • Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions; medRxiv; (2021).

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  • Brains, complex systems and therapeutic opportunities in epilepsy; Seizure; (2021).

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  • Focal dorsal hippocampal nav1.1 knock down alters place cell temporal coordination and spatial behavior; Cerebral Cortex; (2020).

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  • Microelectrode recordings in human epilepsy: a case for clinical translation; Brain Communications; (2020).

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  • Subcortical nuclei volumes are associated with cognition in children post-convulsive status epilepticus: Results at nine years follow-up; Epilepsy and Behavior; (2020).

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  • Headache in children with Sturge-Weber syndrome - Prevalence, associations and impact; European Journal of Paediatric Neurology; (2020).

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  • Current understanding of febrile seizures and their long-term outcomes; Developmental Medicine & Child Neurology; (2020).

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  • Pathophysiology of convulsive status epilepticus; Seizure; (2019).

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  • Long-term outcomes after childhood convulsive status epilepticus; Current Opinion in Pediatrics; (2019).

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  • Intelligence and memory outcomes within 10 years of childhood convulsive status epilepticus; Epilepsy and Behavior; (2019).

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  • Imaging Biomarkers for Febrile Status Epilepticus and Other Forms of Convulsive Status Epilepticus; Imaging Biomarkers in Epilepsy; (2019).

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  • Global development and adaptive behaviour in children with early-onset epilepsy: a population-based case-control study; Developmental Medicine and Child Neurology; (2019).

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  • Experiences and needs of parents of young children with active epilepsy: A population-based study; Epilepsy and Behavior; (2019).

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  • Distributed dynamic coding for spatial working memory in hippocampal-prefrontal networks; bioRxiv; (2019).

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  • Autism, ADHD and parent-reported behavioural difficulties in young children with epilepsy; Seizure; (2019).

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  • Cognitive outcomes following epilepsy in infancy: A longitudinal community-based study; Epilepsia; (2018).

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  • Symptoms of depression, anxiety, and stress in parents of young children with epilepsy: A case controlled population-based study; Epilepsy and Behavior; (2018).

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  • Parenting stress and perceived stigma in mothers of young children with epilepsy: A case-control study; Epilepsy and Behavior; (2018).

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  • Long-term prognosis after childhood convulsive status epilepticus: a prospective cohort study; The Lancet Child and Adolescent Health; (2018).

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  • Long-term behavioural outcomes after paediatric convulsive status epilepticus: a population-based cohort study; Developmental Medicine and Child Neurology; (2018).

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  • Environmental enrichment normalizes hippocampal timing coding in a malformed hippocampus; PLOS ONE; (2018).

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  • WONOEP APPRAISAL: The many facets of epilepsy networks; Epilepsia; (2018).

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  • Child and parental sleep in young children with epilepsy: A population-based case-control study; Epilepsia Open; (2018).

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  • Environmental Enrichment Normalizes Hippocampal Timing Coding in a Malformed Hippocampus; bioRxiv; (2017).

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  • Brain abnormalities in fetuses: in-utero MRI versus ultrasound; The Lancet; (2017).

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  • Auditory processing following infantile spasms: An event-related potential study; Epilepsia; (2017).

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  • Factors associated with reported challenging behavior in young people with epilepsy and neurodevelopmental problems: Data from a specialist epilepsy center; Epilepsia Open; (2017).

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  • Long-term white matter tract reorganization following prolonged febrile seizures; Epilepsia; (2017).

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  • Parent- and Teacher-Reported Symptoms of ADHD in School-Aged Children With Active Epilepsy: A Population-Based Study; Journal of Attention Disorders; (2017).

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  • Methodological standards and functional correlates of depth in vivo electrophysiological recordings in control rodents. A TASK1-WG3 report of the AES/ILAE Translational Task Force of the ILAE; Epilepsia; (2017).

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  • Oscillation phase locking and late ERP components of intracranial hippocampal recordings correlate to patient performance in a working memory task; Frontiers in Human Neuroscience; (2016).

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  • Temporal Coordination of Hippocampal Neurons Reflects Cognitive Outcome Post-febrile Status Epilepticus; EBioMedicine; (2016).

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  • Short-range temporal interactions in sleep; Hippocampal spike avalanches support a large milieu of sequential activity including replay; PLoS ONE; (2016).

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  • Epilepsy and autism spectrum disorders: Relatively related; Neurology; (2016).

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  • Efficacy of nonselective optogenetic control of the medial septum over hippocampal oscillations: The influence of speed and implications for cognitive enhancement; Physiological Reports; (2016).

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  • ACTH prevents deficits in fear extinction associated with early life seizures; Frontiers in Neurology; (2016).

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  • Network science for the identification of novel therapeutic targets in epilepsy [version 1; referees: 2 approved]; Unknown Source; (2016).

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  • T2 relaxation time post febrile status epilepticus predicts cognitive outcome; Experimental Neurology; (2015).

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  • Temporal lobe impairment in west syndrome: Event-related potential evidence; Annals of Neurology; (2015).

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  • Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy; Epilepsy Research; (2015).

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  • Mechanisms responsible for cognitive impairment in epileps; Cold Spring Harbor Perspectives in Medicine; (2015).

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  • Features of developmental coordination disorder in active childhood epilepsy: A population-based study; Developmental Medicine and Child Neurology; (2015).

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  • Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures; Nature Communications; (2015).

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  • State-Dependent Differences in Functional Connectivity in Young Children With Autism Spectrum Disorder; EBioMedicine; (2015).

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  • Quantitative magnetic resonance imaging evidence for altered structural remodeling of the temporal lobe in West syndrome; Epilepsia; (2015).

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  • Factors associated with quality of life in active childhood epilepsy: A population-based study; European Journal of Paediatric Neurology; (2015).

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  • Features of autism spectrum disorder (ASD) in childhood epilepsy: A population-based study; Epilepsy and Behavior; (2015).

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  • The health, education, and social care costs of school-aged children with active epilepsy: A population-based study; Epilepsia; (2015).

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  • Status epilepticus induced spontaneous dentate gyrus spikes: In vivo current source density analysis; PLoS ONE; (2015).

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  • Symptoms of anxiety and depression in school-aged children with active epilepsy: A population-based study; Epilepsy and Behavior; (2015).

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  • Erratum: Status epilepticus induced spontaneous dentate gyrus spikes: In vivo current source density analysis (PLoS ONE (2015) 10:8 (e0136125) DOI: 10.1371/journal.pone.0136125); PLoS ONE; (2015).

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  • Cognition in school-aged children with "active" epilepsy: A population-based study; Journal of Clinical and Experimental Neuropsychology; (2015).

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  • What are the effects of prolonged seizures in the brain?; Epileptic Disorders; (2014).

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  • Screening for mental health disorders in active childhood epilepsy: Population-based data; Epilepsy Research; (2014).

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  • Hippocampal sclerosis and other forms of status epilepticus; Annals of Neurology; (2014).

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  • Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits; Neurobiology of Disease; (2014).

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  • Dexamethasone exacerbates cerebral edema and brain injury following lithium-pilocarpine induced status epilepticus; Neurobiology of Disease; (2014).

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  • Consequences of febrile seizures in childhood; Current Opinion in Pediatrics; (2014).

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  • Cognitive impairment in temporal lobe epilepsy: Role of online and offline processing of single cell information; Hippocampus; (2014).

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  • Attention deficit associated with early life interictal spikes in a rat model is improved with ACTH; PLoS ONE; (2014).

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  • Academic achievement in school-aged children with active epilepsy: A population-based study; Epilepsia; (2014).

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  • A comparison of continuous video-EEG monitoring and 30-minute EEG in an ICU; Epileptic Disorders; (2014).

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  • Neurobehavioral comorbidities in children with active epilepsy: A population-based study; Pediatrics; (2014).

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  • Focal Scn1a knockdown induces cognitive impairment without seizures; Neurobiology of Disease; (2013).

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  • Enrichment and training improve cognition in rats with cortical malformations; PLoS ONE; (2013).

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  • Early developmental outcomes in children following convulsive status epilepticus: A longitudinal study; Epilepsia; (2013).

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  • Diagnosis of probable psychogenic nonepileptic seizures in the outpatient clinic: Does gender matter?; Epilepsy and Behavior; (2013).

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  • Altered short-term plasticity in the prefrontal cortex after early life seizures; Neurobiology of Disease; (2013).

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  • A population-based study of newly diagnosed epilepsy in infants; Epilepsia; (2013).

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  • Hippocampal volume loss following childhood convulsive status epilepticus is not limited to prolonged febrile seizures; Epilepsia; (2013).

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  • Hippocampal interictal epileptiform activity disrupts cognition in humans; Neurology; (2013).

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  • Long-term seizure, cognitive, and psychiatric outcome following trans-middle temporal gyrus amygdalohippocampectomy and standard temporal lobectomy: Clinical article; Journal of Neurosurgery; (2013).

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  • Methylphenidate treatment of attention deficit hyperactivity disorder in young people with learning disability and difficult-to-treat epilepsy: Evidence of clinical benefit; Epilepsia; (2013).

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  • Speed modulation of hippocampal theta frequency correlates with spatial memory performance; Hippocampus; (2013).

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  • Short duration waveforms recorded extracellularly from freely moving rats are representative of axonal activity; Frontiers in neural circuits; (2013).

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  • Prolonged febrile seizures cause reversible reductions in white matter integrity; NeuroImage: Clinical; (2013).

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  • Seizure prognosis of patients with low-grade tumors; Seizure; (2012).

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  • Seizure outcome after extratemporal epilepsy surgery in childhood; Developmental Medicine and Child Neurology; (2012).

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  • SCN1A mutations in Dravet syndrome: Impact of interneuron dysfunction on neural networks and cognitive outcome; Epilepsy and Behavior; (2012).

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  • Recognition memory is impaired in children after prolonged febrile seizures; Brain; (2012).

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  • Psychopathology in children before and after surgery for extratemporal lobe epilepsy; Developmental Medicine and Child Neurology; (2012).

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  • Prediction of seizure outcome in childhood epilepsies in countries with limited resources: A prospective study; Developmental Medicine and Child Neurology; (2012).

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  • Outcome of frontal lobe epilepsy surgery; Epilepsia; (2012).

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  • Maturation of EEG oscillations in children with sodium channel mutations; Brain and Development; (2012).

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  • Lack of efficacy of phenytoin in children presenting with febrile status epilepticus; American Journal of Emergency Medicine; (2012).

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  • Joint time-frequency analysis of EEG signals based on a phase-space interpretation of the recording process; Proceedings of SPIE - The International Society for Optical Engineering; (2012).

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  • Functional network changes in hippocampal CA1 after status epilepticus predict spatial memory deficits in rats; Journal of Neuroscience; (2012).

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  • Febrile seizures and the wandering granule cell; Nature Medicine; (2012).

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  • Before Epilepsy Unfolds: Opening up the potassium door in neonatal seizures; Nature Medicine; (2012).

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  • The role of magnetic resonance imaging in the follow-up of children with convulsive status epilepticus; Developmental Medicine and Child Neurology; (2012).

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  • Imaging seizure-induced inflammation using an antibody targeted iron oxide contrast agent; NeuroImage; (2012).

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  • Seizure outcome in infantile spasms-A retrospective study; Epilepsia; (2011).

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  • Impaired cognition in rats with cortical dysplasia: Additional impact of early-life seizures; Brain; (2011).

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  • Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex; Epilepsy and Behavior; (2011).

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  • Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures; Journal of Neuroscience; (2011).

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  • Outcomes of childhood epilepsy at age 33 years: A population-based birth-cohort study; Epilepsia; (2011).

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  • Epilepsy surgery in children under 3 years; Epilepsy Research; (2011).

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  • Maturational dynamics of hippocampal place cells in immature rats; Hippocampus; (2011).

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  • Death within 8 years after childhood convulsive status epilepticus: A population-based study; Brain; (2011).

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  • Causes of status epilepticus in children; The Causes of Epilepsy: Common and Uncommon Causes in Adults and Children; (2011).

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  • Cognitive outcome after extratemporal epilepsy surgery in childhood; Epilepsia; (2011).

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  • Adverse outcomes following convulsive status epilepticus in children: Relationship with hippocampal injury; Epilepsia; (2010).

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  • Quantitative MRI predicts status epilepticus-induced hippocampal injury in the lithium-pilocarpine rat model; Epilepsy Research; (2010).

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  • Hippocampal interictal spikes disrupt cognition in rats; Annals of Neurology; (2010).

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  • Cognitive and behavioral comorbidities of epilepsy; Epilepsia; (2010).

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  • Cerebral blood flow changes during pilocarpine-induced status epilepticus activity in the rat hippocampus; Experimental Neurology; (2010).

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  • Statistical Process Control (SPC)-A simple objective method for monitoring seizure frequency and evaluating effectiveness of drug interventions in refractory childhood epilepsy; Epilepsy Research; (2010).

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  • Treatment of community-onset childhood convulsive status epilepticus - Authors' reply; The Lancet Neurology; (2009).

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  • Management of convulsive status epilepticus in children; Archives of Disease in Childhood: Education and Practice Edition; (2009).

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  • Impaired everyday memory associated with encephalopathy of severe malaria: The role of seizures and hippocampal damage; Malaria Journal; (2009).

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  • Socioeconomic deprivation independent of ethnicity increases status epilepticus risk; Epilepsia; (2009).

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  • Phenomenology of prolonged febrile seizures: Results of the febstat study; Neurology; (2009).

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  • Status epilepticus in the developing brain: Long-term effects seen in humans; Epilepsia; (2009).

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  • The effects of epilepsy surgery on emotions, behavior, and psychosocial impairment in children and adolescents with drug-resistant epilepsy: A prospective study; Epilepsy and Behavior; (2009).

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  • Is streamlined evaluation of children for epilepsy surgery possible?; Epilepsia; (2008).

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  • Treatment of community-onset, childhood convulsive status epilepticus: a prospective, population-based study; The Lancet Neurology; (2008).

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  • The medical management of the epilepsies in children: conceptual and practical considerations; The Lancet Neurology; (2008).

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  • Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus; Proteomics; (2007).

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  • Outcome of convulsive status epilepticus: A review; Archives of Disease in Childhood; (2007).

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  • Clinical update: childhood convulsive status epilepticus; Lancet; (2007).

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  • Clinical trial design in status epilepticus: Problems and solutions; Epilepsia; (2007).

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  • Childhood convulsive status epilepticus: Epidemiology, management and outcome; Acta Neurologica Scandinavica; (2007).

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  • Autonomic status epilepticus in panayiotopoulos syndrome and other childhood and adult epilepsies: A consensus view; Epilepsia; (2007).

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  • 'Severe memory impairment in a child with bihippocampal injury after status epilepticus' [3]; Developmental Medicine and Child Neurology; (2007).

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  • The epidemiology of convulsive status epilepticus in children: A critical review; Epilepsia; (2007).

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  • Prolonged febrile seizures are associated with hippocampal vasogenic edema and developmental changes; Epilepsia; (2006).

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  • Outcome of paediatric convulsive status epilepticus: a systematic review; Lancet Neurology; (2006).

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  • Incidence, cause, and short-term outcome of convulsive status epilepticus in childhood: prospective population-based study; Lancet; (2006).

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  • Hippocampal sclerosis in children with lesional epilepsy is influenced by age at seizure onset; Epilepsia; (2006).

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  • Cognitive competence at the onset of West syndrome [1]; Developmental Medicine and Child Neurology; (2006).

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  • Childhood convulsive status epilepticus - Authors' reply; Lancet; (2006).

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  • Buccal midazolam as rescue therapy for acute seizures; Lancet Neurology; (2005).

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  • Meningitis is a common cause of convulsive status epilepticus with fever; Archives of Disease in Childhood; (2005).

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  • Nonconvulsive status epilepticus: Epilepsy Research Foundation Workshop Reports; Epileptic Disorders; (2005).

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  • A systematic review of the epidemiology of status epilepticus; European Journal of Neurology; (2004).

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  • Inappropriate emergency management of status epilepticus in children contributes to need for intensive care; Journal of Neurology, Neurosurgery and Psychiatry; (2004).

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  • The acute management of seizures in childhood; Hospital Medicine; (2004).

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  • Hippocampal abnormalities after prolonged febrile convulsion: A longitudinal MRI study; Brain; (2003).

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  • Abnormalities in hippocampi remote from the seizure focus: A T2 relaxometry study; Brain; (2003).

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  • Erratum: Magnetic resonance imaging findings within 5 days of status epilepticus in childhood (Brain (2002) 125:9(1951-1959); Brain; (2002).

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  • Convulsive status epilepticus in children with intractable epilepsy is frequently focal in origin; Canadian Journal of Neurological Sciences; (2002).

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  • Magnetic resonance imaging findings within 5 days of status epilepticus in childhood; Brain; (2002).

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  • Quantitative magnetic resonance characterization of mesial temporal sclerosis in childhood; Neurology; (2001).

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  • Intranasal midazolam for treating febrile seizures in children [5] (multiple letters); British Medical Journal; (2001).

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  • Intranasal midazolam for treating febrile seizures in children; BMJ; (2001).

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  • The treatment of convulsive status epilepticus in children; Archives of Disease in Childhood; (2000).

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  • Buccal midazolam may be a useful alternative to rectal diazepam for treating acute seizures in refractory epilepsy: Commentary; Evidence-Based Medicine; (2000).

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  • Pharmacological management of convulsive status epilepticus in children; Developmental Medicine and Child Neurology; (1999).

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  • Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: A randomised trial; Lancet; (1999).

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  • Buccal midazolam and rectal diazepam for epilepsy (multiple letters) [2]; Lancet; (1999).

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  • Status epilepticus: Pathophysiology, epidemiology, and outcomes; Archives of Disease in Childhood; (1998).

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  • Developmental perspectives on epilepsy; Current Opinion in Neurology; (1998).

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  • Buccal absorption of midazolam: Pharmacokinetics and EEG pharmacodynamics; Epilepsia; (1998).

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  • 'Nasal rather than rectal benzodiazepines in the management of acute childhood seizures?' [1]; Developmental Medicine and Child Neurology; (1997).

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