Natalie Whitlock Stephenson
UX/UI Designer, Senior-
Improved Production and Biophysical Analysis of Recombinant Silicatein-α; Biomolecules; (2020).
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Protein kinase Cα gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulation; Proceedings of the National Academy of Sciences; (2018).
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Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases; Science Signaling; (2018).
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Recurrent MLK4 loss-of-function mutations suppress JNK signalling to promote colon tumorigenesis.; Cancer Research; (2016).
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Somatically mutated ABL1 in an actionable and essential NSCLC survival gene. ; EMBO Molecular Medicine; (2016).
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Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability. ; FEBS Open Bio; (2015).
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Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges. ; Pharmacogenomics; (2015).
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Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. ; Cell; (2015).
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Mixed lineage kinases activate the MEK/ERK pathway independently of the RAF kinases and mediate resistance to RAF inhibitors. ; Nature Communications; (2014).
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). Targeted Genetic Dependency Screen Facilitates Efficient Identification of Actionable Mutations in FGFR4, PAK5, and MAP3K9 in Lung Cancer. ; Proceedings of the National Academy of Science, USA; (2013).
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Protein kinase C delta deficiency causes Mendelian Systemic Lupus Erythematosus with B-cell defective apoptosis and hyperproliferation. ; Arthritis and Rheumatism; (2013).
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Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region. ; Proceedings of the National Academy of Science, USA; (2012).
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