Natalie Whitlock Stephenson

UX/UI Designer, Senior

Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803

Education

  • BSc Applied Biochemistry - The University of Liverpool, School of Biological Sciences, 2008
  • PhD Biomolecular Science - The University of Manchester, Faculty of Life Sciences, 2012

  • Improved Production and Biophysical Analysis of Recombinant Silicatein-α; Biomolecules; (2020).

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  • Protein kinase Cα gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulation; Proceedings of the National Academy of Sciences; (2018).

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  • Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases; Science Signaling; (2018).

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  • Recurrent MLK4 loss-of-function mutations suppress JNK signalling to promote colon tumorigenesis.; Cancer Research; (2016).

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  • Somatically mutated ABL1 in an actionable and essential NSCLC survival gene. ; EMBO Molecular Medicine; (2016).

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  • Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability. ; FEBS Open Bio; (2015).

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  • Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges. ; Pharmacogenomics; (2015).

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  • Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. ; Cell; (2015).

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  • Mixed lineage kinases activate the MEK/ERK pathway independently of the RAF kinases and mediate resistance to RAF inhibitors. ; Nature Communications; (2014).

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  • ). Targeted Genetic Dependency Screen Facilitates Efficient Identification of Actionable Mutations in FGFR4, PAK5, and MAP3K9 in Lung Cancer. ; Proceedings of the National Academy of Science, USA; (2013).

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  • Protein kinase C delta deficiency causes Mendelian Systemic Lupus Erythematosus with B-cell defective apoptosis and hyperproliferation. ; Arthritis and Rheumatism; (2013).

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  • Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region. ; Proceedings of the National Academy of Science, USA; (2012).

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