Amanda Lee Jenkins

Research Program Manager

Nemours Children's Hospital, Florida 6535 Nemours Parkway Orlando, FL 32827

Education

  • Bachelor's of Science (double major) - University of Arizona, Biochemistry & Molecular Biophysics; Molecular & Cellular Biology, 2005
  • Master's of Science - Arizona State University, Molecular & Cellular Biology, 2009

  • Design of a randomized, placebo-controlled study evaluating efficacy and safety of a cancer preventative vaccine in dogs; Veterinary Immunology and Immunopathology; (2024).

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  • Low prevalence of occult cancer diagnosis when screening healthy, higher-risk, middle-aged to older dogs.; Journal of the American Veterinary Medical Association; (2024).

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  • Epithelial cell responses to rhinovirus identify an early-life–onset asthma phenotype in adults; Journal of Allergy and Clinical Immunology; (2022).

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  • The GSDMB rs7216389 SNP is associated with chronic rhinosinusitis in a multi-institutional cohort; International Forum of Allergy and Rhinology; (2021).

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  • RV-C infections result in greater clinical symptoms and epithelial responses compared to RV-A infections in patients with CRS; Allergy: European Journal of Allergy and Clinical Immunology; (2020).

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  • Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19; American Journal of Respiratory and Critical Care Medicine; (2020).

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  • The effect of maxillary sinus antrostomy size on the sinus microbiome; International Forum of Allergy and Rhinology; (2019).

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  • Early life risk factors for chronic sinusitis: A longitudinal birth cohort study; Journal of Allergy and Clinical Immunology; (2018).

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  • Paranasal sinus size is decreased in CFTR heterozygotes with chronic rhinosinusitis; International Forum of Allergy and Rhinology; (2017).

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  • Association between the CDHR3 rs6967330 risk allele and chronic rhinosinusitis; Journal of Allergy and Clinical Immunology; (2017).

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  • Novel role of surfactant protein A in bacterial sinusitis; International Forum of Allergy and Rhinology; (2017).

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  • Dead or alive: Deoxyribonuclease i sensitive bacteria and implications for the sinus microbiome; American Journal of Rhinology and Allergy; (2016).

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  • A Snail1/Notch1 signalling axis controls embryonic vascular development; Nature Communications; (2014).

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  • A 3D matrix platform for the rapid generation of therapeutic anti-human carcinoma monoclonal antibodies; Proceedings of the National Academy of Sciences of the United States of America; (2014).

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  • Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment; Nature Communications; (2014).

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  • Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force; Journal of Cell Biology; (2013).

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  • The histone methyltransferase EZH2 mediates tumor progression on the chick chorioallantoic membrane assay, a novel model of head and neck squamous cell carcinoma; Translational Oncology; (2013).

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  • Inactivation or loss of TTP promotes invasion in head and neck cancer via transcript stabilization and secretion of MMP9, MMP2, and IL-6; Clinical Cancer Research; (2013).

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  • Extracellular matrix determinants and the regulation of cancer cell invasion stratagems; Journal of Microscopy; (2013).

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  • Coupling protein engineering with probe design to inhibit and image matrix metalloproteinases with controlled specificity; Journal of the American Chemical Society; (2013).

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  • Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity; Proceedings of the National Academy of Sciences of the United States of America; (2012).

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  • Pulmonary fibroblasts mobilize the membrane-tethered matrix metalloprotease, MT1-MMP, to destructively remodel and invade interstitial type I collagen barriers; American Journal of Physiology - Lung Cellular and Molecular Physiology; (2011).

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  • Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time; Proceedings of the National Academy of Sciences of the United States of America; (2011).

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  • Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells; European Journal of Cancer; (2008).

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  • The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity; Molecular Cancer Research; (2008).

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