Thomas H Shaffer, PhD

Administration of Drugs/Gene Products to the Respiratory System: A Historical Perspective of the Use of Inert Liquids; Frontiers in Physiology; (2022).

Utilising pneuRIP device in determining the adequacy of respiratory support when weaning high-flow nasal cannula in paediatric patients with acute respiratory distress: A pilot study; Journal of Paediatrics and Child Health; (2022).

Adjustment of high flow nasal cannula rates using real-time work of breathing indices in premature infants with respiratory insufficiency; Journal of Perinatology; (2021).

Automated assessment of thoracic-abdominal asynchrony in patients with morquio syndrome; Diagnostics; (2021).

Effect of positive end-expiratory pressure on additional passive ventilation generated by CPR compressions in a porcine model; Intensive Care Medicine Experimental; (2021).

Machine learning for automatic identification of thoracoabdominal asynchrony in children; Pediatric Research; (2021).

Pulmonary immune cell transcriptome changes in double-hit model of BPD induced by chorioamnionitis and postnatal hyperoxia; Pediatric Research; (2021).

Diagnostic differences in respiratory breathing patterns and work of breathing indices in children with Duchenne muscular dystrophy; PLOS ONE; (2020).

A novel noninvasive approach for evaluating work of breathing indices in a developmental rat model using respiratory inductance plethysmography; Scientific Reports; (2020).

DNA Methylation Profile in Human Cord Blood Mononuclear Leukocytes From Term Neonates: Effects of Histological Chorioamnionitis; Frontiers in Pediatrics; (2020).

Effects of xenon gas on human airway epithelial cells during hyperoxia and hypothermia; Journal of Neonatal-Perinatal Medicine; (2020).

The effect of positive end-expiratory pressure on cardiac output and oxygen delivery during cardiopulmonary resuscitation; Intensive Care Medicine Experimental; (2020).

Age-related ranges of respiratory inductance plethysmography (RIP) reference values for infants and children; Paediatric Respiratory Reviews; (2019).

Histological Chorioamnionitis Induces Differential Gene Expression in Human Cord Blood Mononuclear Leukocytes from Term Neonates; Scientific Reports; (2019).

Cover Image, Volume 53, Number 9, September 2018; Pediatric Pulmonology; (2018).

Measures of respiratory inductance plethysmography (RIP) in children with neuromuscular disease; Pediatric Pulmonology; (2018).

Nebulization of single-chain tissue-type and single-chain urokinase plasminogen activator for treatment of inhalational smoke-induced acute lung injury; Journal of Drug Delivery Science and Technology; (2018).

Impact of endotracheal tube biofilm and respiratory secretions on airway resistance and mechanics of breathing in a neonatal lung model; Journal of Applied Physiology; (2018).

Inflammatory Response of Pulmonary Artery Smooth Muscle Cells Exposed to Oxidative and Biophysical Stress; Inflammation; (2018).

Quantitative Analysis of Thoracoabdominal Asynchrony in Pediatric Polysomnography; Journal of Clinical Sleep Medicine; (2018).

A translational cellular model to study the impact of high-frequency oscillatory ventilation on human epithelial cell function; Journal of Applied Physiology; (2017).

Lung Rest during Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure-Practice Variations and Outcomes; Pediatric Critical Care Medicine; (2017).

Management of Supplemental Oxygen for Infants with Persistent Pulmonary Hypertension of Newborn: A Survey; American Journal of Perinatology; (2017).

Skeletal dysplasia: Respiratory management during infancy; Respiratory Medicine; (2017).

Upper Airway Structure; Fetal and Neonatal Physiology, 2-Volume Set; (2017).

pneuRIPTM: A novel respiratory inductance plethysmography monitor; Journal of Medical Devices, Transactions of the ASME; (2017).

Activity of daily living for Morquio A syndrome; Molecular Genetics and Metabolism; (2016).

Design and testing of a novel slot retractor for neonatal frenotomy; Journal of Clinical Engineering; (2016).

High flow nasal heliox improves work of breathing and attenuates lung injury in a newborn porcine lung injury model; Journal of Neonatal-Perinatal Medicine; (2016).

Parental preferences regarding administration of an animal-derived versus a synthetic medication to newborn infants; Journal of Neonatal-Perinatal Medicine; (2016).

Clinical use of nonconventional modes of ventilator support; Pediatric and Neonatal Mechanical Ventilation: From Basics to Clinical Practice; (2015).

Indications for nonconventional ventilation modes; Pediatric and Neonatal Mechanical Ventilation: From Basics to Clinical Practice; (2015).

Non-invasive pulmonary function test on Morquio patients; Molecular Genetics and Metabolism; (2015).

Pharmacokinetics of gentamicin by intravenous and intratracheal administrations; 2014 IEEE Signal Processing in Medicine and Biology Symposium, IEEE SPMB 2014 - Proceedings; (2015).

Prophylactic methylprednisolone to reduce inflammation and improve outcomes from one lung ventilation in children: A randomized clinical trial; Paediatric Anaesthesia; (2015).

Plp1 gene duplication inhibits airway responsiveness and induces lung inflammation; Pulmonary Pharmacology and Therapeutics; (2015).

High flow nasal cannula (HFNC) with Heliox decreases diaphragmatic injury in a newborn porcine lung injury model; Pediatric Pulmonology; (2014).

The orl rat is more responsive to methacholine challenge than wild type; Pulmonary Pharmacology and Therapeutics; (2014).

Work of breathing indices in infants with respiratory insufficiency receiving high-flow nasal cannula and nasal continuous positive airway pressure; Journal of Perinatology; (2014).

Comparison study of airway reactivity outcomes due to a pharmacologic challenge test: Impulse oscillometry versus least mean squared analysis techniques; Pulmonary Medicine; (2013).

Use of insulin to decrease septic shock-induced myocardial depression in a porcine model; Inflammation; (2013).

Brief mechanical ventilation impacts airway cartilage properties in neonatal lambs; Pediatric Pulmonology; (2012).

Clara cell protein mediates secretion of proteins, IL-8 and IL-6 in human airway epithelial cell line Calu-3 exposed to hyperoxia; Journal of Chemical and Pharmaceutical Research; (2012).

Dosage effects of clara cell 10 kd (cc10) protein on the human airway epithelial cell line Calu-3 under normoxic and hyperoxic conditions; Research Journal of Pharmaceutical, Biological and Chemical Sciences; (2012).

Hyperoxia during one lung ventilation: Inflammatory and oxidative responses; Pediatric Pulmonology; (2012).

Lucinactant attenuates pulmonary inflammatory response, preserves lung structure, and improves physiologic outcomes in a preterm lamb model of RDS; Pediatric Research; (2012).

Neonatal non-invasive respiratory support: Physiological implications; Pediatric Pulmonology; (2012).

Perfluorodecalin lavage of a longstanding lung atelectasis in a child with spinal muscle atrophy; Pediatric Pulmonology; (2012).

Pulmonary function tests in emergency department pediatric patients with acute wheezing/asthma exacerbation; Pulmonary Medicine; (2012).

Respiratory mechanics in an infant with perinatal lethal hypophosphatasia treated with human recombinant enzyme replacement therapy; Pediatric Pulmonology; (2012).

The effects of gas humidification with High-flow nasal cannula on cultured human airway epithelial cells; Pulmonary Medicine; (2012).

Translational research: Matching experimental models with therapeutic interventions; Pediatric Critical Care Medicine; (2012).

Nasal cannula, CPAP, and high-flow nasal cannula: Effect of flow on temperature, humidity, pressure, and resistance; Biomedical Instrumentation and Technology; (2011).

Effect of budesonide in airway epithelial cell line Calu-3 with reduced CFTR function; Journal of Chemical and Pharmaceutical Research; (2011).

Airway injury resulting from repeated endotracheal intubation: Possible prevention strategies; Pediatric Critical Care Medicine; (2011).

Altered properties of human airway epithelial cell line calu-3 with reduced CFTR function; International Journal of Pharmacy and Technology; (2011).

High-flow nasal cannula: Impact on oxygenation and ventilation in an acute lung injury model; Pediatric Pulmonology; (2011).

Perfluorochemical liquid-adenovirus suspensions enhance gene delivery to the distal lung; Pulmonary Medicine; (2011).

Pregnancy and Outcome of Uterine Allotransplantation and Assisted Reproduction in Sheep; Journal of Minimally Invasive Gynecology; (2011).

Reply letter to: RhinoChill: Do we need perfluorocarbons?; Resuscitation; (2011).

Surfactant administration prior to one lung ventilation: Physiological and inflammatory correlates in a piglet model; Pediatric Pulmonology; (2011).

Protective ventilation to reduce inflammatory injury from one lung ventilation in a piglet model; Paediatric Anaesthesia; (2010).

Prototype hybrid systems for neonatal warming: In vitro comparisons to standard of care devices; Biomedical Instrumentation and Technology; (2010).

Skeletal dysplasias: Evaluation with impulse oscillometry and thoracoabdominal motion analysis; Pediatric Pulmonology; (2010).

Clinical design functions: Round table discussions on the bioengineering of liquid ventilators; ASAIO Journal; (2009).

Developmental differences in the contractile response of isolated ovine tracheal smooth muscle cells; Pediatric Pulmonology; (2009).

Efficacy of Chest Physiotherapy in Pediatric Patients with Acute Asthma Exacerbations; Pediatric Asthma, Allergy and Immunology; (2009).

Heat shock protein 70 secretion by neonatal tracheal tissue during mechanical ventilation: Association with indices of tissue function and modeling; Pediatric Research; (2009).

Research in high flow therapy: Mechanisms of action; Respiratory Medicine; (2009).

Intranasal perfluorochemical spray for preferential brain cooling in sheep; Neurocritical Care; (2008).

Assessment of neonatal ventilation during high-frequency oscillatory ventilation; Pediatric Critical Care Medicine; (2008).

Dissociation between the effects of oxygen and pressure on matrix metalloproteinase-2, -7, and -9 expression in human airway epithelial cells; American Journal of Perinatology; (2008).

Effects of oxygen concentration and exposure time on cultured human airway epithelial cells; Pediatric Critical Care Medicine; (2008).

Multicenter comparative study of conventional mechanical gas ventilation to tidal liquid ventilation in oleic acid injured sheep; ASAIO Journal; (2008).

KL4-surfactant (Lucinactant) protects human airway epithelium from hyperoxia; Pediatric Research; (2008).

Low dose methylprednisolone prophylaxis to reduce inflammation during one-lung ventilation; Paediatric Anaesthesia; (2008).

Perfluorochemical augmented rhSOD delivery attenuates inflammation in the immature lung; Journal of Neonatal-Perinatal Medicine; (2008).

Recombinant human Clara cell secretory protein treatment increases lung mRNA expression of surfactant proteins and vascular endothelial growth factor in a premature lamb model of respiratory distress syndrome; American Journal of Perinatology; (2008).

An ultrasound imaging method for in vivo tracheal bulk and Young's moduli of elasticity; Journal of Biomechanics; (2007).

Correlation of tracheal smooth function with structure protein during early development; Pediatric Pulmonology; (2007).

Effects of recombinant Clara cell secretory protein (rhCC10) on inflammatory-related matrix metalloproteinase activity in a preterm lamb model of neonatal respiratory distress; Pediatric Critical Care Medicine; (2007).

Growth and development in a heliox incubator environment: A long-term safety study; Neonatology; (2007).

Sequential alterations of tracheal mechanical properties in the neonatal lamb: Effect of mechanical ventilation; Pediatric Pulmonology; (2007).

Ventilator-induced airway injury: a critical consideration during mechanical ventilation of the infant.; Neonatal network : NN; (2006).

Effects of an intratracheally delivered anti-inflammatory protein (rhCC10) on physiological and lung structural indices in a juvenile model of acute lung injury; Biology of the Neonate; (2006).

The 5th European Symposium on Perfluorocarbon (PFC) application; ASAIO Journal; (2006).

Effects of perfluorochemical evaporative properties on oxygenation during partial liquid ventilation; Pediatrics International; (2006).

Expression of matrix metalloproteinases 2, 7 and 9, and their tissue inhibitors 1 and 2, in developing rabbit tracheae; Biology of the Neonate; (2006).

Matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression profiles in tracheal aspirates do not adequately reflect tracheal or lung tissue profiles in neonatal respiratory distress: Observations from an animal model; Pediatric Critical Care Medicine; (2006).

Optimizing the neonatal thermal environment.; Neonatal network : NN; (2006).

Perfluorochemical liquids enhance delivery of superoxide dismutase to the lungs of juvenile rabbits; Pediatric Research; (2006).

Physiologic implications of helium as a carrier gas for inhaled nitric oxide in a neonatal model of Bethanecol-induced bronchoconstriction; Pediatric Critical Care Medicine; (2006).

Pulmonary function assessment in an infant with Barnes syndrome: Proactive evaluation for surgical intervention; Pediatrics; (2006).

The impact of mechanical ventilation on immature airway smooth muscle: Functional, structural, histological, and molecular correlates; Biology of the Neonate; (2006).

A prototype infant incubator for heliox therapy; Biomedical Instrumentation and Technology; (2006).

Cold perfluorochemical-induced hypothermia protects lung integrity in normal rabbits; Biology of the Neonate; (2005).

The neonatal respiratory pump: a developmental challenge with physiologic limitations.; Neonatal network : NN; (2005).

Tracheal gas insufflation as a lung-protective strategy: Physiologic, histologic, and biochemical markers; Pediatric Critical Care Medicine; (2005).

Differential impact of perfluorochemical physical properties on the physiologic, histologic, and inflammatory profile in acute lung injury; Critical Care Medicine; (2005).

Safety, pharmacokinetics, and anti-inflammatory effects of intratracheal recombinant human Clara cell protein in premature infants with respiratory distress syndrome; Pediatric Research; (2005).

Dose response to rhCC10-augmented surfactant therapy in a lamb model of infant respiratory distress syndrome: Physiological, inflammatory, and kinetic profiles; Journal of Applied Physiology; (2005).

Heliox attenuates lung inflammation and structural alterations in acute lung injury; Pediatric Pulmonology; (2005).

Hyperoxia-induced changes in human airway epithelial cells: The protective effect of perflubron; Pediatric Critical Care Medicine; (2005).

Neonatal chest wall suspension splint: A novel and noninvasive method for support of lung volume; Pediatric Pulmonology; (2005).

Pulmonary applications of perfluorochemical liquids: Ventilation and beyond; Paediatric Respiratory Reviews; (2005).

Recombinant human Clara cell secretory protein in acute lung injury of the rabbit: Effect of route of administration; Pediatric Critical Care Medicine; (2005).

Association of interleukin-8 with inflammatory and innate immune components in bronchoalveolar lavage of children with chronic respiratory diseases; Clinica Chimica Acta; (2004).

Continuous tracheal gas insufflation during partial liquid ventilation in juvenile rabbits with acute lung injury; Journal of Applied Physiology; (2004).

Feasibility of lung cancer hyperthermia using breathable perfluorochemical (PFC) liquids. Part I: Connective hyperthermia; International Journal of Hyperthermia; (2004).

Feasibility of lung cancer hyperthermia using breathable perfluorochemical (PFC) liquids. Part II: Ultrasound hyperthermia; International Journal of Hyperthermia; (2004).

Airway structure, function and development in health and disease; Paediatric Anaesthesia; (2004).

Respiratory Physiology: Structure, Function, and Integrative Responses to Intervention with Special Emphasis on the Ventilatory Pump; Cardiopulmonary Physical Therapy: A Guide to Practice: Fourth Edition; (2004).

Liquid ventilation: An adjunct for respiratory management; Paediatric Anaesthesia; (2004).

Inhaled nitric oxide therapy in the near-term or term neonate with hypoxic respiratory failure.; Neonatal network : NN; (2004).

Tracheal gas insufflation-augmented continuous positive airway pressure in a spontaneously breathing model of neonatal respiratory distress; Pediatric Pulmonology; (2004).

Protein composition of apical surface fluid from the human airway cell line Calu-3: Effect of ion transport mediators; Clinica Chimica Acta; (2004).

Regulation of apical surface fluid and protein secretion in human airway epithelial cell line Calu-3; Biochemical and Biophysical Research Communications; (2004).

Assisted Ventilation: Physiologic Implications and Complications; Fetal and Neonatal Physiology: Third Edition; (2003).

Convective heat transfer during endometrial cryoablation using PFC fluid; Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC; (2003).

Liquid Ventilation; Fetal and Neonatal Physiology: Third Edition; (2003).

Long-term tidal liquid ventilation in premature lambs: Physiologic, biochemical and histological correlates; Biology of the Neonate; (2003).

PIV measurement of fluid flow inside a human uterus model for cryoablation; Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC; (2003).

Perfluorochemical (PFC) combinations for acute lung injury: An in vitro and in vivo study in juvenile rabbits; Pediatric Research; (2003).

Physiologic effects of CPAP: application and monitoring.; Neonatal network : NN; (2003).

Positive end-expiratory pressure modulates perfluorochemical evaporation from the lungs; Biology of the Neonate; (2003).

Respiratory support; Neonatal Respiratory Disorders, Second Edition; (2003).

Special Ventilatory Techniques And Modalities Ii: Lung Protective Strategies and Liquid Ventilation; Assisted Ventilation of the Neonate; (2003).

Upper Airway Structure: Function, Regulation, and Development; Fetal and Neonatal Physiology: Third Edition; (2003).

Transient heat transfer in human endometrium during cryoablation; Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC; (2002).

Distinct patterns of apoptosis in the lung during liquid ventilation compared with gas ventilation; American Journal of Physiology - Lung Cellular and Molecular Physiology; (2002).

Experimental and numerical studies of heat transfer in human uteri during cryoablation; ASME International Mechanical Engineering Congress and Exposition, Proceedings; (2002).

If art imitates life, can laboratory models imitate clinical disease processes?; Critical Care Medicine; (2002).

Managing our first breaths: a reflection on the past several decades of neonatal pulmonary therapy.; Neonatal network : NN; (2002).

Physicochemical properties of perfluorochemical liquids influence ventilatory requirements, pulmonary mechanics, and microvascular permeability during partial liquid ventilation following intestinal ischemia/reperfusion injury; Critical Care Medicine; (2002).

Effects of perfluorochemical distribution and elimination dynamics on cardiopulmonary function; Journal of Applied Physiology; (2001).

A comparison of surfactant delivery with conventional mechanical ventilation and partial liquid ventilation in meconium aspiration injury; Respiratory Medicine; (2001).

Efficacy of specific perfluorocarbons for use in partial liquid ventilation [4] (multiple letters); Critical Care Medicine; (2001).

Intratracheal administration of perfluorochemical-gentamicin suspension: A comparison to intravenous administration in normal and injured lungs; Pediatric Pulmonology; (2001).

Perfluorochemical liquids do not stimulate endothelin-1 or nitric oxide production in human blood leukocytes; Biology of the Neonate; (2001).

Perfluorochemical liquids modulate cell-mediated inflammatory responses; Critical Care Medicine; (2001).

Role of ventilation strategy on perfluorochemical evaporation from the lungs; Journal of Applied Physiology; (2001).

Temperature and heater responses during transition between radiant and incubator thermal environment in newborn preterm lambs; Biology of the Neonate; (2001).

Thermal stability and transition studies with a hybrid warming device for neonates; Journal of Perinatology; (2001).

A perfluorochemical loss/restoration (L/R) system for tidal liquid ventilation; Biomedical Instrumentation and Technology; (2000).

Effects of partial liquid ventilation with perfluorodecalin in the juvenile rabbit lung after saline injury; Critical Care Medicine; (2000).

Liquid ventilation; Seminars in Perinatology; (2000).

Multi-center comparative study of conventional mechanical (CMV) to tidal liquid ventilation (TLV) in oleic acid (OA) injured sheep; Annals of Biomedical Engineering; (2000).

Perfluorochemical elimination from the lungs: Effect of initial dose; Pediatric Pulmonology; (2000).

A method for isolating adult and neonatal airway smooth muscle cells and measuring shortening velocity; Journal of Applied Physiology; (1999).

Airway mechanics in health and disease; New Horizons: Science and Practice of Acute Medicine; (1999).

Effect of single versus multiple dosing on perfluorochemical distribution and elimination during partial liquid ventilation; Pediatric Pulmonology; (1999).

Developmental airway structure and function in health and chronic lung injury; Chronic Lung Disease in Early Infancy; (1999).

Improved pulmonary function after surgical reduction of congenital diaphragmatic hernia in lambs; Journal of Pediatric Surgery; (1999).

Intra-tracheal delivery strategy of gentamicin with partial liquid ventilation; Respiratory Medicine; (1999).

Liquid assisted ventilation update; European Journal of Pediatrics, Supplement; (1999).

Liquid perfluorochemical priming before surfactant therapy: This time the egg really does precede the chicken; Critical Care Medicine; (1999).

Liquid ventilation State-of-the-Art, Part 2; Biomedical Instrumentation and Technology; (1999).

Liquid ventilation state-of-the-art, part I; Biomedical Instrumentation and Technology; (1999).

Liquid ventilation: Clinical experiences; Biomedical Instrumentation and Technology; (1999).

Liquid ventilation: current status.; Pediatrics in review / American Academy of Pediatrics; (1999).

Multifactorial analysis of exchanger efficiency and liquid conservation during perfluorochemical liquid-assisted ventilation; Biomedical Instrumentation and Technology; (1999).

On-line techniques for perfluorochemical vapor sampling and measurement; Biomedical Instrumentation and Technology; (1999).

Software for real-time control of a tidal liquid ventilator; Biomedical Instrumentation and Technology; (1999).

Antenatal triiodothyronine improves neonatal pulmonary function in preterm lambs; Journal of the Society for Gynecologic Investigation; (1998).

Cardiopulmonary interaction during partial liquid ventilation in surfactant-treated preterm lambs; European Journal of Pediatrics; (1998).

Perfluorochemical rescue after surfactant treatment: Effect of perflubron dose and ventilatory frequency; Journal of Applied Physiology; (1998).

Physiologic, biochemical, and histologic correlates associated with tidal liquid ventilation; Pediatric Research; (1998).

Quantitative bronchoscopic assessment of airway collapsibility in newborn lamb tracheae; Pediatric Research; (1998).

A comparison of intratracheal and intravenous administration of gentamicin during liquid ventilation; European Journal of Pediatrics; (1997).

Halothane administration during liquid ventilation; Respiratory Medicine; (1997).

Enhanced distribution of adenovirus-mediated gene transfer to lung parenchyma by perfluorochemical liquid; Human Gene Therapy; (1997).

Comparison of perfluorochemical fluids used for liquid ventilation: Effect of endotracheal tube flow resistance; Pediatric Pulmonology; (1997).

Analysis of perfluorochemical elimination from the respiratory system; Journal of Applied Physiology; (1997).

Liquid-assisted ventilation: From concept to clinical application; Seminars in Neonatology; (1997).

Morphometrics of normal and hypoplastic lungs in preterm lambs with gas and partial liquid ventilation; Pediatric Surgery International; (1997).

Partial liquid ventilation in critically ill infants receiving extracorporeal life support. Philadelphia Liquid Ventilation Consortium.; Pediatrics; (1997).

Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome,Partielle Flüssigkeitsventilation mit Perflubron bei Frühgeborenen mit schwerem Atemnotsyndrom; Pneumologie; (1997).

Pulmonary administration of gentamicin during liquid ventilation in a newborn lamb lung injury model.; Pediatrics; (1997).

Comparison of natural surfactant and briefliquid ventilation rescue treatment in very immature lambs; Neonatology; (1996).

Infant thoracic surgery: Procedure-dependent pulmonary response; Journal of Pediatric Surgery; (1996).

Liquid ventilation in premature lambs: Uptake, biodistribution and elimination of perfluorodecalin liquid; Reproduction, Fertility and Development; (1996).

Liquid ventilation: An alternative ventilation strategy for management of neonatal respiratory distress; European Journal of Pediatrics, Supplement; (1996).

Liquid ventilation: a comprehensive overview.; Neonatal network : NN; (1996).

Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome; New England Journal of Medicine; (1996).

Pulmonary administration of vasoactive substances by perfluorochemical ventilation; Pediatrics; (1996).

Quantitative structure-activity relationships of perfluorinated hetero- hydrocarbons as potential respiratory media: Application to oxygen solubility, partition coefficient, viscosity, vapor pressure, and density; ASAIO Journal; (1996).

Liquid assisted ventilation: An alternative ventilatory strategy for acute meconium aspiration injury; Pediatric Pulmonology; (1996).

Liquid ventilation improves pulmonary function, gas exchange, and lung injury in a model of respiratory failure; Annals of Surgery; (1995).

Combined gas ventilation and perfluorochemical tracheal instillation as an alternative treatment for lethal congenital diaphragmatic hernia in lambs; Journal of Pediatric Surgery; (1995).

Use of liquid ventilation with perflubron during extracorporeal membrane oxygenation: Chest radiographic appearances; Radiology; (1995).

Development and application of a simplified liquid ventilator; Critical Care Medicine; (1995).

Neonatal endotracheal tubes: Variation in airway resistance with different perfluorochemical liquids; Artificial Cells, Blood Substitutes, and Biotechnology; (1994).

Perfluorochemical liquid as a respiratory medium; Artificial Cells, Blood Substitutes, and Biotechnology; (1994).

Utility of a perfluorochemical liquid for pulmonary diagnostic imaging; Artificial Cells, Blood Substitutes, and Biotechnology; (1994).

Lung management with perfluorocarbon liquid ventilation improves pulmonary function and gas exchange during extracorporeal membrane oxygenation (ECMO); Artificial Cells, Blood Substitutes, and Biotechnology; (1994).

Mathematical modeling of perfluorocarbon chemical (PFC) bio-distribution during liquid ventilation of lambs; Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; (1994).

Operative creation of left to right cardiac shunts: Pulmonary functional sequelae; The Annals of Thoracic Surgery; (1993).

Inadvertent administration of positive end-distending pressure during nasal cannula flow; Pediatrics; (1993).

Oxygen consumption and carbon dioxide production during liquid ventilation; Journal of Pediatric Surgery; (1993).

Epithelial modulation of preterm airway smooth muscle contraction; Journal of Applied Physiology; (1993).

High-resolution computed tomographic bronchiolography using perfluoroctylbromide (PFOB): An experimental model; Journal of Thoracic Imaging; (1993).

Effect of exchange transfusion with a red blood cell substitute on neonatal hemodynamics and organ blood flows; Journal of Pediatric Surgery; (1993).

Lung lavage with oxygenated perfluorochemical liquid in acute lung injury; Critical Care Medicine; (1993).

Effect of position on the mechanical interaction between the rib cage and abdomen in preterm infants; Journal of Applied Physiology; (1992).

Comparison of gas and liquid ventilation: Clinical, physiological, and histological correlates; Journal of Applied Physiology; (1992).

Increased respiratory drive and limited adaptation to loaded breathing in bronchopulmonary dysplasia; Pediatric Research; (1992).

Caffeine potentiates airway responsiveness in the neonatal lamb; Pediatric Pulmonology; (1992).

Effects of inspiratory resistive loading on chest wall motion and ventilation: Differences between preterm and full-term infants; Pediatric Research; (1992).

Liquid ventilation.; Pediatric pulmonology; (1992).

Structure-function of airway generations 0 to 4 in the preterm lamb; Pediatric Research; (1992).

Maturational changes in airway smooth muscle structure-function relationships; Pediatric Research; (1992).

Airway responsiveness to low inspired gas temperature in preterm neonates; The Journal of Pediatrics; (1991).

Developmental changes in tracheal structure; Pediatric Research; (1991).

Dissociation between the effects of theophylline and caffeine on premature airway smooth muscle; Pediatric Research; (1991).

Effect of nasal CPAP on thoracoabdominal motion in neonates with respiratory insufficiency; Pediatric Pulmonology; (1991).

Immediate improvement in lung volume after exogenous surfactant: Alveolar recruitment versus increased distention; The Journal of Pediatrics; (1991).

Interaction between chest wall motion and lung mechanics in normal infants and infants with bronchopulmonary dysplasia; Pediatric Pulmonology; (1991).

Reply; The Journal of Pediatrics; (1991).

Structural deformation of the preterm trachea during acute distention and collapse.; Journal of developmental physiology; (1991).

Differential effects of pancuronium bromide on cardiopulmonary function in the neonatal lamb; Pediatric Pulmonology; (1990).

Emergence of the brain-stem auditory evoked potential in the premature lamb; Electroencephalography and Clinical Neurophysiology; (1990).

Liquid ventilation during early development: Theory, physiologic processes and application; Journal of Developmental Physiology; (1990).

Liquid ventilation of human preterm neonates; The Journal of Pediatrics; (1990).

Neonatal gastric intubation: Differential respiratory effects between nasogastric and orogastric tubes; Pediatric Pulmonology; (1990).

Pericardial effects on diastolic ventricular interaction during development; Pediatric Research; (1990).

Theoretical model of ventricular interdependence: Pericardial effects; American Journal of Physiology - Heart and Circulatory Physiology; (1990).

Thoracoabdominal asynchrony in infants with airflow obstruction; American Review of Respiratory Disease; (1990).

Use of a touch sensitive screen and computer assisted image analysis for quantitation of developmental changes in pulmonary structure; Pediatric Pulmonology; (1990).

Effects of intravenous perfluorocarbon and oxygen breathing on acute decompression sickness in the hamster; Undersea Biomedical Research; (1989).

In vivo mechanical properties of the developing airway; Pediatric Research; (1989).

LIQUID VENTILATION OF PRETERM BABY; The Lancet; (1989).

Mechanics and energetics of breathing in newly diagnosed infants with cystic fibrosis: Effect of combined bronchodilator and chest physical therapy; Pediatric Pulmonology; (1989).

Structural changes in the tracheae of preterm lambs induced by ventilation; Pediatric Research; (1989).

A comparison of preterm and adult airway smooth muscle mechanics; Journal of Applied Physiology; (1989).

Developmental differences in tracheal cartilage mechanics; Pediatric Research; (1989).

Effect of ventilation on mechanical properties and pressure-flow relationships of immature airways; Pediatric Research; (1988).

A new experimental approach for the study of cardiopulmonary physiology during early development; Journal of Applied Physiology; (1988).

Developmental changes in diastolic ventricular interaction; Pediatric Research; (1988).

Effect of tracheal smooth muscle tone on collapsibility of immature airways; Journal of Applied Physiology; (1988).

Evaluation of neonatal pulmonary mechanics and energetics: A two factor least mean square analysis; Pediatric Pulmonology; (1988).

Fluorocarbon ventilation: Maximal expiratory flows and CO2 elimination; Pediatric Research; (1988).

Influence of smooth muscle tone and longitudinal tension on the collapsibility of immature airways; Pediatric Pulmonology; (1988).

Predictive changes in ventricular interdependence; Annals of Biomedical Engineering; (1988).

A brief review: liquid ventilation.; Undersea Biomedical Research; (1987).

A new approach to induced hypothermia; Journal of Surgical Research; (1986).

A theoretical and experimental model of ventricular interdependence; Basic Research in Cardiology; (1986).

The effect of tracheal smooth muscle tone on neonatal airway collapsibility; Pediatric Research; (1986).

Pulmonary vascular resistance in the fluorocarbon-filled lung; Journal of Applied Physiology; (1986).

Effect of high-frequency jet ventilation on preterm and rabbit tracheal mechanics; Pediatric Pulmonology; (1986).

Acquired Tracheomegaly in Very Preterm Neonates; American Journal of Diseases of Children; (1986).

The role of tracheal smooth muscle contraction on neonatal tracheal mechanics; Pediatric Research; (1986).

A theoretical and experimental model of ventricular interdependence; Federation Proceedings; (1985).

Developmental alterations in pulmonary function of the lamb; Respiration; (1985).

In-vivo evaluation of interfacial surface tension on developmental lung mechanics; Federation Proceedings; (1985).

Preterm infants: Ventilation and P100 changes with CO2 and inspiratory resistive loading; Journal of Applied Physiology; (1985).

Gallbladder mechanics in newborn piglets; Pediatric Research; (1984).

A fine structure study of the liquid-ventilated newborn rabbit lung; Federation Proceedings; (1984).

Effect of external inspiratory loading on ventilation of premature infants; Pediatric Research; (1984).

Liquid ventilation: Effects on pulmonary function in distressed meconium-stained lambs; Pediatric Research; (1984).

Mechanics and energetics of breathing helium in infants with bronchopulmonary dysplasia; The Journal of Pediatrics; (1984).

Physiological effects of ventilation with liquid fluorocarbon at controlled temperatures; Undersea Biomedical Research; (1984).

Tracheal volume deformation in a developmental rabbit model; Neonatology; (1984).

Cardiopulmonary function in very preterm lambs during liquid ventilation; Pediatric Research; (1983).

Decompression incidence in air- and liquid-breathing hamsters; Undersea Biomedical Research; (1983).

Effect of liquid ventilation on preterm lamb tracheal mechanics; Biology of the Neonate; (1983).

The effects of liquid ventilation on cardiopulmonary function in preterm lambs.; Pediatric research; (1983).

Effect of low-rate intermittent mandatory ventilation on pulmonary function of low-birth-weight infants; The Journal of Pediatrics; (1982).

Respiratory muscle function, assessment, and training; Physical Therapy; (1982).

Time-dependent tracheal deformation in fetal, neonatal, and adult rabbits; Pediatric Research; (1982).

Effect of intermittent positive pressure application on the bulk modulus of the developing rabbit trachea; Respiration; (1981).

Increased pulmonary vascular resistance during liquid ventilation; Undersea Biomedical Research; (1981).

Instrumentation for measuring cardiac output by direct Fick method during liquid ventilation; Undersea Biomedical Research; (1981).

Pressure-induced deformation in immature airways; Pediatric Research; (1981).

Pressure-volume relationships of tracheae in fetal newborn and adult rabbits; Respiration Physiology; (1981).

Successful extubation of neonates: clinical and physiological factors.; Critical care medicine; (1981).

Use of external expiratory resistance in intubated neonates to increase lung volume; Archives of Disease in Childhood; (1981).

Alterations in bulk modulus of tracheae during development; Respiration; (1980).

Clinical assessment of pulmonary function in the neonate; Clinics in Chest Medicine; (1980).

SMALL VOLUME PLETHYSMOGRAPHIC RECORDINGS USING A CAPACITIVE TRANSDUCER.; Multi-phase Transport: Fundamentals, Reactor Safety, Applications; (1980).

Sequential effects of acute meconium obstruction on pulmonary function; Pediatric Research; (1980).

The effect of external expiratory resistance on lung volume and pulmonary function in the neonate; The Journal of Pediatrics; (1980).

A new device for diagnosis and treatment of neonatal pneumothorax; Pediatrics; (1979).

Cardiopulmonary changes in the crying neonate; Pediatric Research; (1979).

Effects of endotracheal tube leaks on functional residual capacity determination in intubated neonates; Pediatric Research; (1979).

Improved oxygenation and lung compliance withprone positioning of neonates; The Journal of Pediatrics; (1979).

Low rate intermittent mandatory ventilation (IMV) in the neonate; Anesthesiology; (1979).

Liquid ventilation: Cardiovascular adjustments with secondary hyperlactatemia and acidosis; Journal of Applied Physiology Respiratory Environmental and Exercise Physiology; (1979).

A closed system device for diagnosis and evaluation of neonatal pneumothoraces.; Critical care medicine; (1978).

A Method for Measuring Functional Residual Capacity in Neonates with Endotracheal Tubes; IEEE Transactions on Biomedical Engineering; (1978).

Alterations in pulmonary function of premature lambs due to positive end-expiratory pressure; Respiration; (1978).

Error Analysis for Vector Scope Measurement of Pulmonary Mechanics; IEEE Transactions on Biomedical Engineering; (1978).

Positive end expiratory pressure: Effects on lung mechanics of premature lambs; Biology of the Neonate; (1978).

Pulmonary lavage in preterm lambs; Pediatric Research; (1978).

Pulmonary physiotherapy in neonates: Physiologic changes and respiratory management; The Journal of Pediatrics; (1978).

Effect of positive end expiratory pressure on lung mechanics of premature lambs; Federation Proceedings; (1977).

Instrumentation for measuring functional residual capacity in small animals; Journal of Applied Physiology Respiratory Environmental and Exercise Physiology; (1977).

The Interaction of FRC and Ventilation on Occlusion Pressure in Conscious Man; IEEE Transactions on Biomedical Engineering; (1977).

Tracheal extubation of the neonate at 2 to 3 cm H2O continuous positive airway pressure; Pediatrics; (1977).

Gaseous exchange and acid-base balance in premature lambs during liquid ventilation since birth; Pediatric Research; (1976).

Pulmonary function in premature lambs during the first few hours of life; Respiration Physiology; (1976).

An Electromechanical Demand Regulated Liquid Breathing System; IEEE Transactions on Biomedical Engineering; (1975).

Limitations of Frequency Dependence as a Measure of Airway Obstruction; IEEE Transactions on Biomedical Engineering; (1975).

Liquid breathing trials and animal studies with a demand regulated liquid breathing system; Medical Instrumentation; (1975).

Demand controlled liquid ventilation of the lungs; Journal of Applied Physiology; (1974).