Thierry G Morlet, PhD

Sr Research Scientist

Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803

Biography

Thierry Morlet, PhD is a Senior Research Scientist and Head of the Auditory Physiology and Psychoacoutics Laboratory at Nemours Children's Health, Adjunct Professor in Communication Sciences and Disorders, College of Health Sciences at the University of Delaware, Adjunct Assistant Professor in the Department of Linguistics and Cognitive Science, College of Arts and Science at the University of Delaware, and Adjunct Faculty at the Georges Osborne College of Audiology, Salus University. With a PhD in Neuroscience from the University of Lyon (France), Dr. Morlet has a broad background in human auditory and vestibular physiology and has extensively studied otoacoustic emissions, efferent auditory pathways and event-related potentials in the normally functioning and diseased auditory systems of children and adults. He is a member of the cochlear implant program, the "Hear We Go" 5K run/walk committee and the auditory processing disorder program at Nemours. He has authored or co-authored more than 60 articles on the development of hearing, pediatric hearing loss, vestibular and balance disorders, auditory processing disorders, auditory neuropathy spectrum disorder and inner ear malformations and is a co-editor of the "Manual of Pediatric Balance Disorders".

Medical/Dental School

  • PhD Neurosciences - Claude Bernard University Lyon 1, 1997

  • Auditory Neuropathy
  • Auditory Neurosciences
  • Event Related Potentials
  • Hearing Loss

  • Clinical management guidelines for Friedreich ataxia: best practice in rare diseases.; Orphanet journal of rare diseases; (2022).

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  • Hearing outcomes in children with Congenital Cytomegalovirus: A multi-center, single-enterprise experience.; International journal of pediatric otorhinolaryngology; (2022).

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  • Evoking responses of central auditory system II - Testing midbrain pathways and cortical projection pathways. Differential Diagnostic Applications of AMLR.; Basic Concepts of Clinical Electrophysiology in Audiology; (2022).

  • Mutations in LOXHD1 gene can cause auditory neuropathy spectrum disorder; Otolaryngology Case Reports; (2021).

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  • Neuropathies post-synaptiques: Caractéristiques et performances auditives. Synthèse sur la physiopathologie et ses conséquences sur la prise en charge; Les Cahiers de l'Audition ; (2021).

  • Auditory Neuropathy, Cochlear Nerve Deficiency and Other Challenges in the Pediatric Population; Cochlear implants and other implantable hearing devices. 2nd Edition; (2020).

  • Genomics and hearing loss: Towards a new standard of care?; Advances in Audiology, Speech Pathology, and Hearing Science; (2020).

  • Manual of Pediatric Balance Disorders. 2nd Edition; Plural Publishing. San Diego, CA; (2020).

  • Physiology and maturation of balance mechanisms; Manual of Pediatric Balance Disorders. 2nd Edition; (2020).

  • Cochlear implantation in a patient with mucopolysaccharidosis IVA.; SAGE open medical case reports; (2019).

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  • Auditory Neuropathy Spectrum Disorder; The SAGE Encyclopedia of Human Communication Sciences and Disorders; (2019).

  • Auditory event-related potentials and function of the medial olivocochlear efferent system in children with auditory processing disorders; International Journal of Audiology; (2019).

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  • Cofactors of Pediatric Tinnitus: A Look at the Whole Picture; Clinical Pediatrics; (2019).

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  • Development of the Vestibular System and of Balance Function: Differential Diagnosis in the Pediatric Population; Dizziness and Vertigo Across the Lifespan; (2019).

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  • Recessive GM3 synthase deficiency: Natural history, biochemistry, and therapeutic frontier; Molecular Genetics and Metabolism; (2019).

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  • Tablet-Based Hearing Test among Child Clinical Populations: Performance and Preference; Telemedicine and e-Health; (2019).

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  • Auditory function in Pelizaeus-Merzbacher disease; Journal of Neurology; (2018).

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  • Is there a clinical application for tablet-based automated audiometry in children?; International Journal of Pediatric Otorhinolaryngology; (2018).

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  • Neurophysiology of hearing in patients with mucopolysaccharidosis type IV; Molecular Genetics and Metabolism; (2018).

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  • Spectre des neuropathies auditives: quelle strategie pour l'appareillage ? ; Connaissances Surdites. ACFOS; (2017).

  • Cochlear Nerve Deficiency and Brain Abnormalities in Pediatric Patients; Otology and Neurotology; (2017).

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  • Activity of daily living for Morquio A syndrome; Molecular Genetics and Metabolism; (2016).

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  • Auditory Neuropathy Spectrum Disorder (ANSD); Sataloff's Comprehensive Textbook of Otolaryngology; (2016).

  • Prevalence of auditory processing disorder in school-aged children in the mid-atlantic region; Journal of the American Academy of Audiology; (2016).

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  • Speech errors among children with auditory processing disorder; Proceedings of Meetings on Acoustics; (2016).

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  • Ganglioside GM3 is essential for the structural integrity and function of cochlear hair cells.; Human molecular genetics; (2015).

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  • CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ lon protease; American Journal of Human Genetics; (2015).

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  • Speech perception capabilities in children a few years after initial diagnosis of auditory processing disorder; Proceedings of Meetings on Acoustics; (2015).

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  • Consensus clinical management guidelines for Friedreich ataxia.; Orphanet journal of rare diseases; (2014).

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  • A homozygous SLITRK6 nonsense mutation is associated with progressive auditory neuropathy in humans; Laryngoscope; (2014).

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  • Ear effect and gender difference of spontaneous otoacoustic emissions in children with auditory processing disorder; Proceedings of Meetings on Acoustics; (2014).

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  • Clinical characteristics of children with cochlear nerve dysplasias; Laryngoscope; (2013).

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  • Clinical characteristics of pediatric granular myringitis; Otolaryngology - Head and Neck Surgery (United States); (2013).

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  • Current and future research and challenges; Manual of Pediatric Balance Disorders; (2013).

  • Current issues in auditory neuropathy spectrum Disorder; Translational Perspectives in Auditory Neurosciences. Special Topics; (2013).

  • Differentiating ANSD from CAPD; Auditory Processing Disorders: Assessment, Management and Treatment. Second Edition; (2013).

  • Manual of Pediatric Balance Disorders. 1st Edition; Unknown Source; (2013).

  • Physiology and maturation of balance mechanisms; Manual of Pediatric Balance Disorders; (2013).

  • Vestibular and balance testing in childhood migraine.; The Laryngoscope; (2012).

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  • Auditory nerve function following cochleitis; International Journal of Pediatric Otorhinolaryngology; (2012).

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  • Speech production-perception relationships in children with speech delay; 13th Annual Conference of the International Speech Communication Association 2012, INTERSPEECH 2012; (2012).

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  • Hearing loss in children with mitochondrial disorders; International Journal of Pediatric Otorhinolaryngology; (2011).

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  • Development of the vestibular system and balance function: Differential diagnosis in the pediatric population; Otolaryngologic Clinics of North America; (2011).

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  • Comprehensive vestibular and balance testing in the dizzy pediatric population; Otolaryngology - Head and Neck Surgery; (2011).

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  • Trouble du traitement de l'audition et neuropathie auditive / Désynchronisation auditive, diagnostic différentiel ; Les Cahiers de l'Audition ; (2011).

  • Central auditory processing deficiency with anatomic deficit in left superior temporal lobe; Laryngoscope; (2010).

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  • Multi-site diagnosis and management of 260 patients with auditory neuropathy/dys-synchrony (auditory neuropathy spectrum disorder; International Journal of Audiology; (2010).

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  • Prevalence of vestibular and balance disorders in children; Otology and Neurotology; (2010).

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  • Ophthalmologic disorders in children with syndromic and nonsyndromic hearing loss; Archives of Otolaryngology - Head and Neck Surgery; (2010).

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  • Chapter XI: Differences between diagnoses of auditory neuropathy/auditory dyssynchrony and (central) auditory processing disorders,Différences entre les diagnostics de neuropathie auditive/ désynchronisation auditive et de troubles (centraux) du traitement de l'audition; Cahiers de l'Audition; (2008).

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  • Chapter XV: Neuropathy, synaptopathy, sensory involvement, partial forms of neuropathy, new etiologies: Variations on a known topic,Neuropathie, synaptopathie, atteinte sensorielle, formes partielles de neuropathie, nouvelles étiologies: Variations sur un thème connu; Cahiers de l'Audition; (2008).

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  • Chapter XVII: Auditory neuropathy/auditory dyssynchrony: Development of a database,Neuropathie auditive / désynchronisation auditive: Elaboration d'une base de données; Cahiers de l'Audition; (2008).

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  • Balance in healthy individuals assessed with Equitest: Maturation and normative data for children and young adults; International Journal of Pediatric Otorhinolaryngology; (2007).

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  • Chapter IX: Function of the outer hair cells and auditory neuropathy/auditory dyssynchronization,Chapitre IX: Fonction des cellules ciliées externes et neuropathie auditive / désynchronisation auditive; Cahiers de l'Audition; (2007).

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  • Pediatric cartilage interleave tympanoplasty; Otolaryngology - Head and Neck Surgery; (2007).

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  • Speech perception in children with speech sound disorder; International Speech Communication Association - 8th Annual Conference of the International Speech Communication Association, Interspeech 2007; (2007).

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  • OTOF mutations revealed by genetic analysis of hearing loss families including a potential temperature sensitive auditory neuropathy allele; Journal of Medical Genetics; (2006).

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  • Vestibular assessment with Balance Quest. Normative data for children and young adults; International Journal of Pediatric Otorhinolaryngology; (2006).

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  • The battery principle re-visited physiologically, with special attention to auditory neuropathy and cued speech.; Perspectives on Hearing and Hearing Disorders in Childhood; (2005).

  • Connexin 26 variants and auditory neuropathy/dys-synchrony among children in schools for the deaf; American Journal of Medical Genetics; (2005).

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  • Absent or elevated middle ear muscle reflexes in the presence of normal otoacoustic emissions: A universal finding in 136 cases of auditory neuropathy/dys-synchrony; Journal of the American Academy of Audiology; (2005).

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  • Assessment of medial olivocochlear system function in pre-term and full-term newborns using a rapid test of transient otoacoustic emissions; Clinical Otolaryngology and Allied Sciences; (2004).

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  • Olivocochlear efferent suppression in classical musicians; Journal of the American Academy of Audiology; (2003).

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  • Fast ForWord™: Its scientific basis and treatment effects on the human efferent auditory system; The Brain and Sensory Plasticity: Language Acquisition and Hearing; (2003).

  • Auditory neuropathy/dyssynchrony its diagnosis and management; Pediatric Clinics of North America; (2003).

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  • Auditory Neuropathy/Dys-Synchrony: Diagnosis and Management; Mental Retardation and Developmental Disabilities Research Reviews; (2003).

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  • Development of auditory asymmetry in transient evoked otoacoustic emissions in pre-term infants; Journal of the American Academy of Audiology; (2003).

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  • Development of auditory asymmetry in transient evoked otoacoustic emissions in pre-term infants.; Journal of the American Academy of Audiology; (2003).

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  • TEOAE recording protocols revised: Data from adult subjects; International Journal of Audiology; (2003).

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  • Preoperative speech and pure-tone audiometry in four types of patients with acoustic neuroma; American Journal of Otolaryngology - Head and Neck Medicine and Surgery; (2003).

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  • Auditory neuropathy/dys-synchrony: After the diagnosis, then what?; Seminars in Hearing; (2002).

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  • Considerations in the clinical evaluation of auditory neuropathy/auditory dys-synchrony; Seminars in Hearing; (2002).

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  • The physiological bases of audiological management; Hair cell micromechanics and otoacoustic emissions; (2002).

  • [Hearing disorders screening in neonates at risk]; Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris; (2001).

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  • Hearing disorders screening in neonates at risk,Dépistage des troubles auditifs chez des nouveau-nés í risque.; Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris; (2001).

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  • Effect of sleep stages on synchronized spontaneous otoacoustic emissions in pre-term neonates; Clinical Neurophysiology; (2000).

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  • Optimization of TEOAE recording protocols. A linear protocol derived from parameters of a time-frequency analysis: a pilot study on neonatal subjects; Scandinavian Audiology; (2000).

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  • Development of human cochlear active mechanism asymmetry: Involvement of the medial olivocochlear system?; Hearing Research; (1999).

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  • Erratum: Development of human cochlear active mechanism asymmetry: Involvement of the medial olivocochlear system? (Hearing Research (1999) 134 (153-162) PII: S0378595599000787); Hearing Research; (1999).

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  • Maturation of brainstem auditory evoked potentials in preterm neonates: Influence of gestational age and gender,Maturation des potentiels evoques auditifs precoces chez le premature: Influence de l'age gestationnel et du sexe; Archives de Pediatrie; (1999).

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  • Auditory screening in high-risk pre-term and full-term neonates using transient evoked otoacoustic emissions and brainstem auditory evoked potentials; International Journal of Pediatric Otorhinolaryngology; (1998).

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  • Peripheral auditory lateralization,Existence d'une latéralisation de l'appareil auditif périphérique.; Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris; (1998).

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  • Evidence of peripheral hearing asymmetry in humans: Clinical implications; Acta Oto-Laryngologica; (1997).

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  • Development of cochlear active mechanisms in humans differs between gender; Neuroscience Letters; (1996).

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  • Type of initial brainstem auditory evoked potentials (BAEP) impairment and risk factors in premature infants; Brain and Development; (1996).

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  • Contralateral suppression of evoked otoacoustic emissions and detection of a multi-tone complex in noise; Acta Oto-Laryngologica; (1995).

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  • Spontaneous and evoked otoacoustic emissions in pre-term and full-term neonates: is there a clinical application?; International Journal of Pediatric Otorhinolaryngology; (1995).

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  • Spontaneous otoacoustic emissions in preterm neonates: prevalence and gender effects; Hearing Research; (1995).

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  • Contralateral auditory stimulation and otoacoustic emissions: A review of basic data in humans; British Journal of Audiology; (1994).

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  • Effect of sleep stages on transiently evoked oto-acoustic emissions in infants; Brain and Development; (1994).

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  • Functional maturation of cochlear active mechanisms and of the medial olivocochlear system in humans; Acta Oto-Laryngologica; (1993).

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