Rheumatology Research
Understanding Autoimmune & Inflammatory Disease in Children
Researchers at Nemours Children’s study how immune signaling contributes to autoimmune diseases, such as juvenile idiopathic arthritis, lupus, and vasculitis, and how inflammation from these conditions damages developing organs and joints.
Through laboratory science, advanced diagnostic testing, and clinical expertise in pediatric rheumatology, we work to detect autoimmune disease earlier and develop precise treatments for children.
Key Areas of Research
Immune System Triggers of Autoimmune Disease | Studying how immune signals become overactive or misdirected and contribute to chronic disease.
Inflammation & Tissue Damage | Investigating how ongoing inflammation affects joints, blood vessels, skin, and internal organs as children grow, and how these changes influence long-term health.
Autoantibodies & Immune Biomarkers | Identifying immune markers in blood that help physicians diagnose autoimmune disease and monitor disease activity over time.
Precision Diagnostics for Autoimmune Disease | Developing laboratory tests that improve diagnostic accuracy and help doctors diagnose inflammatory disease sooner so children can start treatment earlier.
Clinical Trials & Studies at Nemours
Our investigators conduct clinical and laboratory research that help doctors understand how autoimmune diseases develop and how treatments affect children over time. These studies help refine diagnostic tools, evaluate new approaches to care, and improve how inflammation is monitored as a child grows.
Families interested in participating in research can explore current studies across Nemours.
Where Rheumatology Research Happens
Rheumatology research at Nemours takes place across the Delaware Valley and Florida. Pediatric rheumatologists and scientists collaborate to study autoimmune and inflammatory diseases that affect children.
Our teams work to translate research findings into better tools and treatments for children with complex rheumatologic conditions.
Related Research
Center for Clinical Diagnostics
DELAWARE VALLEY
We provide diagnostic testing services that support clinicians and researchers in diagnosing and monitoring pediatric diseases more effectively.
Rheumatology Research, Central Florida
CENTRAL FLORIDA
Our researchers focus on improving care for children with autoimmune and inflammatory conditions, including juvenile arthritis and lupus.
Translational Rheumatology Research Lab
DELAWARE VALLEY
We study how juvenile idiopathic arthritis develops and use advanced tools to predict disease progression, supporting earlier, more effective treatment for better long-term outcomes.