PhITT Study for Teens Working on a Healthy Weight
A Study of Phentermine for Teens Working on a Healthy Weight
The PhITT Study is investigating whether phentermine, alongside support for healthy lifestyle changes, is safe and effective for adolescents ages 12 to 17 who are working on a healthy weight. Phentermine is a pill that is approved for weight loss in adults and teens older than 16 years for a short period of time. Researchers hope to find out if phentermine is effective for weight loss in younger teens and for a longer period of time.
Study Location | Status
Nemours Children’s Health, Delaware | Enrolling
Participant Eligibility
Clinical trials have requirements that determine eligibility. Key requirements are listed below. Please note there may be additional qualifications.
Participants must be/have:
- Ages 12 to 17 when they enroll.
- Have a body mass index (BMI) of 30 or higher, or a BMI at or above the 95th percentile
About the Study
Formal Study Name: Phentermine’s Impact on Treatment in Teens (PhITT)
Study Type: Interventional (researchers intervene and assign treatments)
Study ID: NCT07282340
Completion Date: January 2028
Enrollment/Participant Goal: 200
What’s Involved
The study will take one year and there is no cost to participate.
Participants can expect to:
- Attend clinic visits: Visit the clinic every four weeks, for a total of 16 visits.
- Receive a study assignment: Be placed in a group that receives phentermine or a placebo.
- Complete testing: Have blood and urine tests during the study.
- Build healthy habits: Receive materials and tools that support healthy lifestyle changes.
How This Study Fits in
This study reflects our broader commitment at Nemours to improve care through research. Clinical trials like this one are shaped by the expertise of our medical teams and research programs. Learn how related research and clinical care support, and are strengthened by, studies like this one.
More About Clinical Trials
Learn what to expect from a clinical trial — how they work, why they matter, and what to consider when deciding if one is right for your child.
Learn Strategies to Help Teens Achieve a Healthy Weight From Nemours KidsHealth®
Weight is only one part of a child’s overall health. Learn how doctors assess weight-related health concerns and how families can support healthy eating, activity, and sleep habits from experts at Nemours KidsHealth.