Pharmacokinetics/Safety Profile of Digoxin in Infants With Single Ventricle Congenital Heart Disease

Clinical Trial

Offered by: Nemours Children's
Location: Delaware Valley

Trial Name

Pharmacokinetics/Safety Profile of Digoxin in Infants With Single Ventricle Congenital Heart Disease

What is the trial about?

The purpose of this study is to collect information about the safety effects of digoxin and to learn more about how it is processed in the bodies of children with single ventricle congenital heart disease.

Who can participate?

The study will include infants with single ventricle congenital heart disease who are less than 6 months of age.

What is involved?

If you decide to allow your child to participate in this study, they will be in the study for up to 7 months.

We will collect blood samples from your child to measure the amount of digoxin in their blood using pharmacokinetic (PK) tests and to measure two biomarkers that are used to assess heart function. We will also record the results of tests, exams, and procedures that your child receives as part of their standard medical care, as well as those that may be performed specifically for research study purposes.