Offered by: Nemours Children's
Locations: Delaware Valley and Jacksonville, Orlando and Pensacola in Florida
Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients.
Compare effects of the chemotherapy drugs carboplatin and isotretinoin on participants with high risk medulloblastoma and to find out if one or both are better than standard therapy alone.
> 3 and < 22 yrs of age.
Length of study is 9-15 months. Standard cancer care including additional hearing and blood tests.
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