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Clinical Trial

Offered by: Nemours Children's
Location: Delaware Valley

Trial Name

Treatment of Progressive Early-Onset Spinal Deformities

What is the trial about?

The purpose of this study is to develop an understanding of operative and non-operative treatment to allow spinal growth in patients with early onset scoliosis.

Who can participate?

  • Children under 18 and with any diagnosis, who undergo a growth-friendly surgical procedure, including but not limited to growing rods, VEPTR (Vertical Expandable Prosthetic Titanium Rib), Shilla, hybrid constructs, spinal tethering and staples.
  • Children under 18 and with any diagnosis, who undergo casting.
  • Children 10 and younger with any diagnosis, who undergo spinal fusion of the thoracic and/or lumbar spine.
  • Children <6 with any diagnosis and with scoliosis curves of the thoracic and/or lumbar spine measuring >25 degrees.

What is involved?

The study includes several visits: preoperative, first erect visit and annually after surgery. The following procedures are routine during the visit with the physician:

  • Clinical examination
  • Pulmonary function test (possible)
  • CT scan (possible)
  • X-rays
  • Questionnaires
  • Clinical photos

Contact Nemours Children's Clinical Trials

Trial Name: The Treatment of Progressive Early-Onset Spinal Deformities: A Multicenter Outcome Study

IRB#: 82191

(800) 354-5690 Email Us

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Two researchers in a lab wearing coats and gloves, one looks into a microscope.