About the Motor Neuron Diseases Research Lab
The overall goals of our research program are to understand the mechanisms of degeneration of motor neurons and to develop therapeutic candidates for motor neuron diseases. We use a combination of biochemical, genetic, cell biological, anatomic, pharmacological and behavioral methods to study neurodegeneration and neuroprotection.
Our primary focus is on childhood onset motor neuron diseases such as spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS) and distal hereditary motor neuronopathies (HMNs). However, the approaches we use can also be applied to other neurodegenerative diseases as well as to neuronal injury.