Center for Pharmacogenomics & Translational Research

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Advancing Personalized Medicine for Children

The Center for Pharmacogenetics & Translational Research at Nemours Children’s in North Florida is transforming the future of personalized medicine for kids. We work to ensure that every child has the right medication at the right dose at the right time. By studying how genes can affect response to medicine, we’re redefining treatments for conditions like respiratory diseases, depression, and gastrointestinal disorders.

Since 1989, our Center has grown into a nationally recognized leader in pediatric pharmacogenomics, beginning our work in asthma medications. As a founding member of the American Lung Association Airways Clinical Research Centers network, we helped to establish one of the largest biorepositories for pediatric respiratory research in the country, located in Delaware Valley. We collaborate with researchers from leading academic institutions such as the University of Florida, Johns Hopkins University School of Medicine, Harvard’s Brigham and Women’s Hospital, and others to drive discoveries in pediatric pharmacogenomics.

The center is dedicated to advancing pediatric health through cutting-edge pharmacogenomics and translational science. Our mission is to deliver precision medicine solutions by integrating research, clinical care, and education, training the next generation of scientists while enhancing patient outcomes through personalized therapeutic strategies.

Beyond research, we provide clinical pharmacogenomics services for children. We bring genetic testing into everyday medical care, helping doctors to make personalized medication decisions.

Pioneers in Pharmacogenomics Research

Our work, spanning respiratory diseases, depression, gastrointestinal disorders,  and drug metabolism, places us at the forefront in pharmacogenomics research and innovative solutions.

$10 M +

Research funding for clinical studies

110+

Clinical trials 

500,000

Biospecimens collected for the lung health cohort study

We're leaders in the American Lung Association Airways Clinical Research Centers network which has conducted 25 large clinical trials funded by NIH, the American Lung Association, and pharmaceutical industry, many studying genes that influence the response to treatments tested.


With funding from the National Human Genome Research Institute, the National Heart, Lung, and Blood Institute, and others, we conduct high-impact research that makes a difference in the lives of children.


We advance new understandings of pediatric precision medicine into clinical practice.


We help to train the next generation of researchers and clinicians.

Our Leadership

Portrait of Kathryn Blake.

Kathryn Blake, PharmD, BCPS, FCCP, CIP

Director, Center for Pharmacogenomics and Translational Research

Professor of Pharmacy, Mayo Clinic College of Medicine and Science

Principal Research Scientist, Division of Pulmonology Nemours Children's Health 

Research Team