James P Franciosi, MD

Gastroenterologist

Nemours Children's Hospital, Florida 6535 Nemours Parkway Orlando, FL 32827

Biography

Dr. Franciosi has been the Division Chief of Pediatric Gastroenterology at Nemours Children's Hospital for the past six years and Professor of Pediatrics at the University of Central Florida College of Medicine in Orlando, Florida. He was an inaugural faculty at Nemours Children's Hospital, leaving Cincinnati Children's Hospital Medical Center in 2012 to build pediatric gastroenterology services in a leadership role at this new institution. He accomplished an accelerated Pediatric Residency and Pediatric Gastroenterology, Hepatology and Nutrition training program at the Children's Hospital of Philadelphia. During this time, Dr. Franciosi also obtained a Master's Degree in Clinical Research at the University of Pennsylvania, Perelman School of Medicine. His present academic pursuits are in the fields of pediatric esophageal disorders such as eosinophilic esophagitis and gastroesophageal reflux disease, pharmacogenomics, and in telehealth. He has published over 100 abstracts and peer-reviewed publications, has developed an internationally recognized patient-reported outcome questionnaire, launched the first pediatric transnasal esophagoscopy program in the Southeast, and has been awarded over a million dollars in external research funding. He is acknowledged for his "servant leadership" skill set, innovation, work ethic, sense of humor and collaborative spirit.

Fellowship

  • Pediatric Gastroenterology - Children's Hospital of Philadelphia, 2008

Residency

  • Surgery - University of Texas Southwestern Medical Center, 2003

Internship Residency

  • Pediatrics - The Children's Hospital of Philadelphia, 2005

Medical/Dental School

  • MD - Medical College of Wisconsin, 2001

Board Certifications

  • American Board of Pediatrics/General Pediatrics
  • American Board of Pediatrics/Gastroenterology

  • Comparative Effectiveness of Intravenous Azithromycin Versus Erythromycin Stimulating Antroduodenal Motility in Children.; Journal of pediatric gastroenterology and nutrition; (2022).

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  • A Provider-Focused Intervention to Promote Optimal Care of Pediatric Patients With Suspected Elbow Fracture.; Pediatric emergency care; (2021).

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  • Pharmacogenomics fail to explain proton pump inhibitor refractory esophagitis in pediatric esophageal atresia.; Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society; (2021).

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  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing.; Clinical pharmacology and therapeutics; (2020).

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  • STAT6 Variants Associate With Relapse of Eosinophilic Esophagitis in Patients Receiving Long-term Proton Pump Inhibitor Therapy.; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association; (2020).

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  • COVID-19-A Guide to Rapid Implementation of Telehealth Services: A Playbook for the Pediatric Gastroenterologist.; Journal of pediatric gastroenterology and nutrition; (2020).

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  • CYP2C19 and STAT6 Variants Influence the Outcome of Proton Pump Inhibitor Therapy in Pediatric Eosinophilic Esophagitis.; Journal of pediatric gastroenterology and nutrition; (2019).

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  • Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene-drug pairs across ambulatory care settings.; Genetics in medicine : official journal of the American College of Medical Genetics; (2019).

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  • Symptom Burden and Quality of Life Over Time in Pediatric Eosinophilic Esophagitis.; Journal of pediatric gastroenterology and nutrition; (2019).

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  • Promoting Adherence to Influenza Vaccination Recommendations in Pediatric Practice.; Journal of primary care & community health; (2019).

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  • Genotype tailored treatment of mild symptomatic acid reflux in children with uncontrolled asthma (GenARA): Rationale and methods.; Contemporary clinical trials; (2019).

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  • Novel Implementation of Genotype-Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial.; Clinical and translational science; (2018).

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  • Provider-Focused Intervention to Promote Comprehensive Screening for Adolescent Idiopathic Scoliosis by Primary Care Pediatricians.; American journal of medical quality : the official journal of the American College of Medical Quality; (2018).

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  • Perceived medication adherence barriers mediating effects between gastrointestinal symptoms and health-related quality of life in pediatric inflammatory bowel disease.; Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation; (2017).

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  • Association between CYP2C19 extensive metabolizer phenotype and childhood anti-reflux surgery following failed proton pump inhibitor medication treatment.; European journal of pediatrics; (2017).

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  • Association Between CYP2C19*17 Alleles and pH Probe Testing Outcomes in Children With Symptomatic Gastroesophageal Reflux.; Journal of clinical pharmacology; (2017).

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