Zubairul H. Aghai, MD

Neonatologist

Nemours Children's Health, Philadelphia 833 Chestnut St. E. Suite 300 - Specialty Care Philadelphia, PA 19107

Fellowship

  • Neonatology - Weill Cornell Medical College, 2000

Residency

  • Pediatrics - Wayne State University, 1997

Education

  • MD - Government Medical College, Nagpur, India, 1988

  • Evaluation of Gastroesophageal Reflux in Symptomatic Young Infants Using Multichannel Intraluminal pH-Impedance Testing: A large Cohort Study from a Single Center; American Journal of Perinatology; (2024).

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  • Iron Deficiency Prior to Discharge in Very Low Birth Weight Infants: Screening with Reticulocyte Hemoglobin Content; American Journal of Perinatology; (2024).

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  • Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study; Journal of Perinatology; (2024).

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  • Hyperoxia-Induced miR-195 Causes Bronchopulmonary Dysplasia in Neonatal Mice; Biomedicines; (2024).

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  • Acute Kidney Injury and Abnormalities on Brain Magnetic Resonance Imaging or Death in Infants with Hypoxic–Ischemic Encephalopathy: A Case–Control Study; American Journal of Perinatology; (2024).

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  • Is it time to study routine car seat tolerance screening in a randomized controlled trial? An international survey of current practice and clinician equipoise; Journal of Perinatology; (2022).

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  • Growth failure in infants with neonatal abstinence syndrome in the neonatal intensive care unit; Journal of Perinatology; (2022).

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  • Comprehensive Serological Profile and Specificity of Maternal and Neonatal Cord Blood SARS CoV-2 Antibodies; Unknown Source; (2021).

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  • Pulmonary immune cell transcriptome changes in double-hit model of BPD induced by chorioamnionitis and postnatal hyperoxia.; Pediatric research; (2021).

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  • Neonatal intensive care unit admissions before and after the adoption of the baby friendly hospital initiative.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2020).

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  • Influence of Patient Characteristics on Antibiotic Use Rates Among Preterm Infants.; Journal of the Pediatric Infectious Diseases Society; (2020).

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  • Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry; Reproductive Health; (2020).

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  • Neonatal Early-Onset Sepsis Calculator and Antibiotic Therapy.; JAMA pediatrics; (2020).

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  • Is Maternal Methadone Dose Associated with the Severity of Neonatal Abstinence Syndrome?; American journal of perinatology; (2020).

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  • Management of infants born to mothers with chorioamnionitis: A retrospective comparison of the three approaches recommended by the committee on fetus and newborn.; Journal of neonatal-perinatal medicine; (2020).

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  • A novel noninvasive approach for evaluating work of breathing indices in a developmental rat model using respiratory inductance plethysmography.; Scientific reports; (2020).

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  • A comparison of Triple I classification with neonatal early-onset sepsis calculator recommendations in neonates born to mothers with clinical chorioamnionitis; Journal of Perinatology; (2020).

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  • DNA Methylation Profile in Human Cord Blood Mononuclear Leukocytes From Term Neonates: Effects of Histological Chorioamnionitis.; Frontiers in pediatrics; (2020).

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  • miR-184 mediates hyperoxia-induced injury by targeting cell death and angiogenesis signalling pathways in the developing lung.; The European respiratory journal; (2020).

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  • Prevalence and Utility of Low Mean Corpuscular Volume in Infants Admitted to the Neonatal Intensive Care Unit.; The Journal of pediatrics; (2020).

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  • Do extremely preterm infants need retinopathy of prematurity screening earlier than 31 weeks postmenstrual age?; Journal of perinatology : official journal of the California Perinatal Association; (2020).

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  • Prolonging gavage feeds for reduction of gastroesophageal reflux in infants.; Journal of perinatology : official journal of the California Perinatal Association; (2020).

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  • Stopping caffeine in premature neonates: how long does it take for the level of caffeine to fall below the therapeutic range?; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2020).

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  • Hyperoxia causes miR199a-5p-mediated injury in the developing lung.; Pediatric research; (2019).

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  • Hypertensive disorders during pregnancy are associated with reduced severe intraventricular hemorrhage in very-low-birth-weight infants.; Journal of perinatology : official journal of the California Perinatal Association; (2019).

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  • Use of a Modified Early-Onset Sepsis Risk Calculator for Neonates Exposed to Chorioamnionitis.; The Journal of pediatrics; (2019).

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  • Histological Chorioamnionitis Induces Differential Gene Expression in Human Cord Blood Mononuclear Leukocytes from Term Neonates.; Scientific reports; (2019).

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  • Maternal breast milk feeding and length of treatment in infants with neonatal abstinence syndrome.; Journal of perinatology : official journal of the California Perinatal Association; (2019).

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  • Identification of new biomarkers of bronchopulmonary dysplasia using metabolomics.; Metabolomics : Official journal of the Metabolomic Society; (2019).

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  • Response to Dr. Kumar's letter.; Journal of perinatology : official journal of the California Perinatal Association; (2019).

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  • Early airway microbial metagenomic and metabolomic signatures are associated with development of severe bronchopulmonary dysplasia.; American journal of physiology. Lung cellular and molecular physiology; (2018).

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  • Infants Born to Mothers with Clinical Chorioamnionitis: A Cross-Sectional Survey on the Use of Early-Onset Sepsis Risk Calculator and Prolonged Use of Antibiotics.; American journal of perinatology; (2018).

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  • Reply.; The Journal of pediatrics; (2018).

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  • Umbilical cord milking for neonates who are depressed at birth: a randomized trial of feasibility.; Journal of perinatology : official journal of the California Perinatal Association; (2018).

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  • Association between early antibiotic exposure and bronchopulmonary dysplasia or death.; Journal of perinatology : official journal of the California Perinatal Association; (2018).

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  • Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6.; Stem cell research & therapy; (2018).

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  • Adverse effects of small for gestational age differ by gestational week among very preterm infants.; Archives of disease in childhood. Fetal and neonatal edition; (2018).

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  • Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants.; JCI insight; (2018).

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  • Exclusive breast feeding and dehydration fever in newborns during the first days of life.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2018).

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  • Is early-onset sepsis risk calculator safe for the management of neonates born to mothers with chorioamnionitis?; Journal of perinatology : official journal of the California Perinatal Association; (2018).

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  • Apgar Scores at 10 Minutes and Outcomes in Term and Late Preterm Neonates with Hypoxic-Ischemic Encephalopathy in the Cooling Era.; American journal of perinatology; (2018).

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  • Do infants in the neonatal intensive care unit diagnosed with urinary tract infection need a routine voiding cystourethrogram?; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2017).

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  • Utility of Early-Onset Sepsis Risk Calculator for Neonates Born to Mothers with Chorioamnionitis.; The Journal of pediatrics; (2017).

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  • Car Seat Tolerance Screening in the Neonatal Intensive Care Unit: Failure Rates, Risk Factors, and Adverse Outcomes.; The Journal of pediatrics; (2017).

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  • Nasogastric Feeding Tubes May Not Contribute to Gastroesophageal Reflux in Preterm Infants.; American journal of perinatology; (2017).

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  • Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs.; Nature communications; (2017).

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  • Lung Rest During Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure-Practice Variations and Outcomes.; Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies; (2017).

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  • Utility of measuring direct bilirubin at first 72 h of age in neonates admitted to the neonatal intensive care unit.; Journal of perinatology : official journal of the California Perinatal Association; (2017).

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  • Reply.; The Journal of pediatrics; (2016).

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  • The Airway Microbiome at Birth.; Scientific reports; (2016).

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  • Continuous Positive Airway Pressure versus Mechanical Ventilation on the First Day of Life in Very Low-Birth-Weight Infants.; American journal of perinatology; (2016).

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  • Temporal Association Between Reflux-like Behaviors and Gastroesophageal Reflux in Preterm and Term Infants.; Journal of pediatric gastroenterology and nutrition; (2016).

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  • High Flow Nasal Cannula Use Is Associated with Increased Morbidity and Length of Hospitalization in Extremely Low Birth Weight Infants.; The Journal of pediatrics; (2016).

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  • Effects of Multiple Ventilation Courses and Duration of Mechanical Ventilation on Respiratory Outcomes in Extremely Low-Birth-Weight Infants.; JAMA pediatrics; (2015).

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  • Feeding tolerance in preterm infants on noninvasive respiratory support.; The Journal of perinatal & neonatal nursing; (2014).

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  • Early caffeine therapy for prevention of bronchopulmonary dysplasia in preterm infants.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2014).

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  • Role of guidelines on length of therapy in chorioamnionitis and neonatal sepsis.; Pediatrics; (2014).

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  • Limb hypoplasia resulting from intrauterine infection with herpes simplex virus: a case report.; Journal of perinatology : official journal of the California Perinatal Association; (2014).

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  • Detection of pepsin in mouth swab: correlation with clinical gastroesophageal reflux in preterm infants.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2013).

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  • Sirtuin1 in tracheal aspirate leukocytes: possible role in the development of bronchopulmonary dysplasia in premature infants.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2012).

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  • IFN-γ and IP-10 in tracheal aspirates from premature infants: relationship with bronchopulmonary dysplasia.; Pediatric pulmonology; (2012).

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  • Impact of histological chorioamnionitis on tracheal aspirate cytokines in premature infants.; American journal of perinatology; (2012).

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  • Severe pulmonary hypertension with therapeutic L-lysine ibuprofen in 2 preterm neonates.; Pediatrics; (2012).

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  • Utility of performing routine head ultrasounds in preterm infants with gestational age 30-34 weeks.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2011).

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  • Rickettsial diseases in central India: proposed clinical scoring system for early detection of spotted fever.; Indian pediatrics; (2011).

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  • First responder performance in pediatric trauma: a comparison with an adult cohort.; Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies; (2011).

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  • Twice-weekly fluconazole prophylaxis in premature infants: association with cholestasis.; Pediatrics international : official journal of the Japan Pediatric Society; (2011).

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  • Effects of prenatal exposure to cigarette smoke on use of xanthine and pneumogram evaluation at discharge in premature infants.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; (2011).

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  • Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung.; Pediatric research; (2011).

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  • A role for matrix metalloproteinase 9 in IFNγ-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia.; American journal of respiratory cell and molecular biology; (2011).

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  • The effect of comprehensive infection control measures on the rate of late-onset bloodstream infections in very low-birth-weight infants.; American journal of perinatology; (2010).

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  • High-mobility group box-1 protein in tracheal aspirates from premature infants: relationship with bronchopulmonary dysplasia and steroid therapy.; Journal of perinatology : official journal of the California Perinatal Association; (2010).

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  • Intractable neonatal seizures: an unusual presentation of congenital hypothyroidism.; Journal of pediatric endocrinology & metabolism : JPEM; (2009).

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  • Pepsin, a marker of gastric contents, is increased in tracheal aspirates from preterm infants who develop bronchopulmonary dysplasia.; Pediatrics; (2008).

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  • A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome.; Journal of immunology (Baltimore, Md. : 1950); (2008).

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  • Angiopoietin 2 concentrations in infants developing bronchopulmonary dysplasia: attenuation by dexamethasone.; Journal of perinatology : official journal of the California Perinatal Association; (2007).

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  • Azithromycin suppresses activation of nuclear factor-kappa B and synthesis of pro-inflammatory cytokines in tracheal aspirate cells from premature infants.; Pediatric research; (2007).

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  • Fluconazole prophylaxis in extremely low birth weight infants: association with cholestasis.; Journal of perinatology : official journal of the California Perinatal Association; (2006).

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  • Pepsin, a reliable marker of gastric aspiration, is frequently detected in tracheal aspirates from premature ventilated neonates: relationship with feeding and methylxanthine therapy.; Journal of pediatric gastroenterology and nutrition; (2006).

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  • Synchronized nasal intermittent positive pressure ventilation (SNIPPV) decreases work of breathing (WOB) in premature infants with respiratory distress syndrome (RDS) compared to nasal continuous positive airway pressure (NCPAP).; Pediatric pulmonology; (2006).

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  • Work of breathing using high-flow nasal cannula in preterm infants.; Journal of perinatology : official journal of the California Perinatal Association; (2006).

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  • Dexamethasone suppresses expression of Nuclear Factor-kappaB in the cells of tracheobronchial lavage fluid in premature neonates with respiratory distress.; Pediatric research; (2006).

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  • Work of breathing during nasal continuous positive airway pressure in preterm infants: a comparison of bubble vs variable-flow devices.; Journal of perinatology : official journal of the California Perinatal Association; (2005).

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  • Changes in lung volume and work of breathing: A comparison of two variable-flow nasal continuous positive airway pressure devices in very low birth weight infants.; Pediatric pulmonology; (2003).

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  • Respiratory burst activity in bronchopulmonary dysplasia and changes with dexamethasone.; Pediatric pulmonology; (2003).

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  • Spectral characteristics of airway opening and chest wall tidal flows in spontaneously breathing preterm infants.; Journal of applied physiology (Bethesda, Md. : 1985); (2003).

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  • Basement membrane biomarkers in very low birth weight premature infants. Association with length of NICU stay and bronchopulmonary dysplasia.; Biology of the neonate; (2002).

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