Deepthi Alapati, MD


Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Other Offices

Get to Know Me

As a neonatologist, my job is providing the best and most up-to-date care for sick babies. They are the reason I am also a scientist, conducting research in the laboratory to discover new treatments for neonatal diseases that don’t yet have a cure. I was born and raised in India and moved to the United States several years ago.

Why I Treat Children

I love babies and children. I feel like I’m treating the whole family when I help its most important member get well. And I love the challenges of working in a complex, constantly evolving field like pediatrics.

What I'm Passionate About

Research into neonatal lung disease and translating the findings into medical practice to improve health outcomes. I study bronchopulmonary dysplasia, a chronic lung disease usually found in preemies or underweight full-term infants, and pulmonary hypertension, which happens when a newborn fails to transition to normal heart-lung circulation.

How I Try to Make A Difference

My research background helps me to think critically and be a better doctor. So many new things are coming up every day that can lead to better treatments. I believe in evidence-based medicine and family-centered care, and I use it in my practice.

Education & Training


  • Neonatology - University of Miami, 2012

Internship Residency

  • Pediatrics - Lincoln Medical and Mental Health Center Program, 2009

Medical/Dental School

  • MBBS - Madras Medical College, 2005

Board Certifications

  • American Board of Pediatrics/Neonatal-Perinatal Medicine
  • American Board of Pediatrics/General Pediatrics

Awards & Recognition

  • 2020 Pediatric Scientific Abstract Award, American Thoracic Society Pediatric Program Committee

Insurance Accepted

  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas Delaware
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Delaware First Health
  • Delaware Medicaid/Diamond State
  • Delaware Medicare
  • Devon Health Services
  • Fidelis Care NJ Medicaid HMO
  • First Health/Affordable PPO
  • Geisinger Health Plan Commercial
  • Global Medical Managment DE/PA
  • Health Partners Medicaid/Kidz Partner HMO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Medicaid Health Options
  • Horizon Blue Cross Blue Shield of New Jersey
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Interlink Transplant
  • Keystone First Medicaid HMO
  • Lifetrac Transplant
  • Maryland Medicaid
  • Multiplan PPO
  • National Transplant (Humana)
  • New Jersey Medicaid
  • Pennsylvania Medicaid
  • Plan Vista/NPPN PPO
  • Preferred Healthcare PPO
  • Private Health Care Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Star Healthcare Network
  • Three Rivers Provider Network
  • Tricare/Humana Military Health Services
  • United Healthcare of the Mid-Atlantic
  • US Family Health Plan
  • Wellpoint Maryland Medcaid

Research Activities

  • Bronchopulmonary dysplasia
  • Pulmonary hypertension

Medical Interests

  • Lung development
  • Lung diseases

  • Shrestha, D., Ye, G. X., Stabley, D., Betal, S. G., Zhu, Y., Glazewski, L., & Alapati, D. (2021). Pulmonary immune cell transcriptome changes in double-hit model of BPD induced by chorioamnionitis and postnatal hyperoxia. Pediatric Research, 90(3), 565-575. doi:10.1038/s41390-020-01319-z

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  • Behere, S., Alapati, D., & McCulloch, M. A. (2019). Screening Echocardiography and Brain Natriuretic Peptide Levels Predict Late Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia. Pediatric Cardiology, 40(5), 973-979. doi:10.1007/s00246-019-02100-8

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  • Alapati, D., Zacharias, W. J., Hartman, H. A., Rossidis, A. C., Stratigis, J. D., Ahn, N. J., & Peranteau, W. H. (2019). In utero gene editing for monogenic lung disease. Science Translational Medicine, 11(488). doi:10.1126/scitranslmed.aav8375

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  • Costa, J., Zhu, Y., Cox, T., Fawcett, P., Shaffer, T., & Alapati, D. (2018). Inflammatory Response of Pulmonary Artery Smooth Muscle Cells Exposed to Oxidative and Biophysical Stress. Inflammation, 41(4), 1250-1258. doi:10.1007/s10753-018-0772-0

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  • Alapati, D., Jassar, R., & Shaffer, T. H. (2017). Management of Supplemental Oxygen for Infants with Persistent Pulmonary Hypertension of Newborn: A Survey. American Journal of Perinatology, 34(3), 276-282. doi:10.1055/s-0036-1586754

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  • Gien, J., Murthy, K., Pallotto, E. K., Brozanski, B., Chicoine, L., Zaniletti, I., & Children's Hospitals Neonatal Consortium CDH Study Group. (2017). Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH). Early Human Development, 106-107, 7-12. doi:10.1016/j.earlhumdev.2017.01.010

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  • Alapati, D., & Morrisey, E. E. (2017). Gene editing and genetic lung disease basic research meets therapeutic application. American Journal of Respiratory Cell and Molecular Biology, 56(3), 283-290. doi:10.1165/rcmb.2016-0301PS

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  • Alapati, D., Aghai, Z. H., Hossain, M. J., Dirnberger, D. R., Ogino, M. T., & Shaffer, T. H. (2017). Lung Rest during Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure-Practice Variations and Outcomes. Pediatric Critical Care Medicine, 18(7), 667-674. doi:10.1097/PCC.0000000000001171

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  • Alapati, D., & Shaffer, T. H. (2017). Skeletal dysplasia: Respiratory management during infancy. Respiratory Medicine, 131, 18-26. doi:10.1016/j.rmed.2017.07.063

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  • English