Annemarie C. Brescia, MD


Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Education & Training


  • Pediatric Rheumatology - Nemours/Alfred I. duPont Hospital for Children, 2004

Internship Residency

  • Pediatrics - St. Christopher's Hospital for Children, 2001

Medical/Dental School

  • MD - New York University School of Medicine, 1998

Board Certifications

  • American Board of Pediatrics/Pediatric Rheumatology
  • American Board of Pediatrics/General Pediatrics

Awards & Recognition

  • 2014 Delaware Today magazine, Top Doctors

Insurance Accepted

  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas Delaware
  • Carefirst MD Community Health Plan Mcaid
  • Cigna Lifesource Transplant
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Delaware Medicaid/Diamond State
  • Delaware Medicare
  • Devon Health Services
  • Fidelis Care NJ Medicaid HMO
  • First Health/Affordable PPO
  • Geisinger Health Plan Commercial
  • Global Medical Managment DE/PA
  • Health Partners Medicaid/Kidz Partner HMO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Medicaid Health Options
  • Horizon Blue Cross Blue Shield of New Jersey
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Keystone First Medicaid HMO
  • Lifetrac Transplant
  • Maryland Medicaid
  • Multiplan PPO
  • National Transplant (Humana)
  • New Jersey Medicaid
  • Pennsylvania Medicaid
  • Plan Vista/NPPN PPO
  • Preferred Healthcare PPO
  • Private Health Care Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Tricare/Humana Military Health Services
  • United Healthcare of the Mid-Atlantic
  • US Family Health Plan
  • Wellpoint Maryland Medcaid

  • Juvenile Idiopathic Arthritis
  • Juvenile Rheumatoid Arthritis

  • Simonds, M. M., Schlefman, A. R., McCahan, S. M., Sullivan, K. E., Rose, C. D., & Brescia, A. M. C. (2021). The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes. Pediatric Rheumatology, 19(1). doi:10.1186/s12969-021-00556-8

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  • de Jesus, A. A., Hou, Y., Brooks, S., Malle, L., Biancotto, A., Huang, Y., & Goldbach-Mansky, R. (2020). Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. Journal of Clinical Investigation, 130(4), 1669-1682. doi:10.1172/JCI129301

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  • Simonds, M. M., Schlefman, A. R., McCahan, S. M., Sullivan, K. E., Rose, C. D., & Brescia, A. M. C. (2020). Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation. Pediatric Rheumatology, 18(1). doi:10.1186/s12969-020-00483-0

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  • Brescia, A. M. C., Simonds, M. M., McCahan, S. M., Sullivan, K. E., & Rose, C. D. (2018). Prior to extension, transcriptomes of fibroblast-like synoviocytes from extended and polyarticular juvenile idiopathic arthritis are indistinguishable. Pediatric Rheumatology, 16(1). doi:10.1186/s12969-017-0217-6

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  • Brescia, A. C., Simonds, M. M., Sullivan, K. E., & Rose, C. D. (2017). Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis. Proteomics - Clinical Applications, 11(5-6). doi:10.1002/prca.201600088

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  • Schlefman, A. R., Brescia, A. C., Leffler, M. G., & Rose, C. D. (2017). Unilateral Periorbital Swelling in Two Previously Healthy Females. Global Pediatric Health, 4. doi:10.1177/2333794X17733860

  • English