Edward Anders Kolb, MD


Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Other Offices

Get to Know Me

It’s important that the treatment experience is as personal and comfortable as possible for every family. Our department has its own Family Advisory Council whose input helped bring lots of improvements – like room service, refrigerators, prayer groups, better food, and better access to social support. Making life easier for these families is a huge priority for me.

Why I Treat Children

Even sick kids are kids at heart (as I am), just looking for a smile, some fun, a connection with the team members who take care of them. I make it my business to make life better for these kids and their families – as a doctor and through research into promising new drugs.

What I'm Passionate About

I’m a firm believer in clinical trials. In fact, about 80% of our patients are enrolled in clinical trials through the Nemours Center for Cancer and Blood Disorders, and the Nemours Center for Childhood Cancer Research, where I’m director of both. This number is much higher than for adults with cancer, and much higher for children with other kinds of diseases. We also participate in the national Pediatric Preclinical Testing Program, which makes new therapies available for kids sooner. In our department, participating in clinical trials and research studies is the standard of our family-centered care.

Education & Training


  • Pediatric Hematology/Oncology - Memorial Sloan Kettering Cancer Center, 2002

Internship Residency

  • Pediatrics - St. Christophers Hospital for Children, 1999

Medical/Dental School

  • MD - Jefferson Medical College, 1996

Board Certifications

  • American Board of Pediatrics/Pediatric Hematology-Oncology

Awards & Recognition

  • 2021 Lifetime Achievement Honoree, The Leukemia & Lymphoma Society
  • 2016 Philadelphia Magazine's Top Doctors
  • 2014 Best Doctors in America
  • 2014 Delaware Today magazine, Top Doctors
  • 2013 Appointed member of the Scientific Council, Children’s Oncology Group (COG)
  • 2013 Best Doctors in America
  • 2013 Chair, Myeloid Disease Committee, Children’s Oncology Group (COG)
  • 2002 Merit Award, American Society of Clinical Oncology
  • 2012 Resident Educator of the Month
  • 2011 Best Doctors in America
  • 2011 Leukemia & Lymphoma Society, Man of the Year Candidate (Runner-up)
  • 2011 Nemours, Physician Award for Excellence in Scholarship
  • 2010 Nemours Alfred I. duPont Hospital for Children, Physician of the Year
  • 2007 Member, Society for Pediatric Research

Insurance Accepted

  • Aetna Better Health FL Medicaid and Healthy Kids
  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas Delaware
  • AvMed
  • Blue Cross and Blue Shield HMO
  • Blue Cross and Blue Shield Non HMO
  • Blue Cross Blue Shield Florida Blue Select
  • Carefirst MD Community Health Plan Mcaid
  • Cigna & Great West HMO/POS Open Access
  • Cigna & Great West PPO/EPO
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Community Care Plan Medicaid
  • Delaware First Health
  • Delaware Medicaid/Diamond State
  • Delaware Medicare
  • Devon Health Services
  • Employers Health Network PPO
  • Evolutions Healthcare
  • Fidelis Care NJ Medicaid HMO
  • First Health Aetna PPO/EPO
  • First Health/Affordable PPO
  • Florida Medicaid
  • Geisinger Health Plan Commercial
  • Global Medical Managment DE/PA
  • Health First Health Plans
  • Health Partners Medicaid/Kidz Partner HMO
  • HealthSmart Health Plans PPO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Blue Cross Blue Shield of Delaware *PA Loc Contiguous to DE*
  • Highmark Blue Cross Blue Shield of Delaware *PA Loc NONContiguous to DE*
  • Highmark Blue Cross Blue Shield of Pennsylvania
  • Highmark Medicaid Health Options
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana HMO/POS
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Interlink Transplant
  • Keystone First Medicaid HMO
  • Lifetrac Transplant
  • Maryland Medicaid
  • Molina Healthcare Medicaid
  • Multiplan PPO
  • New Jersey Medicaid
  • Olympus Managed Healthcare PPO DE/PA
  • Olympus Managed Healthcare PPO ORL
  • Pennsylvania Medicaid
  • Plan Vista/NPPN PPO
  • Preferred Healthcare PPO
  • Private Health Care Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Seminole Tribe of Florida
  • Simply Healthcare Healthy Kids
  • Simply Healthcare Medicaid HMO
  • Star Healthcare Network
  • Three Rivers Provider Network
  • Tricare/Humana Military Health Services/CHAMPVA
  • United Healthcare of the Mid-Atlantic
  • US Family Health Plan
  • Wellpoint Maryland Medcaid

  • Blood and Bone Marrow Transplantation
  • Blood Disorders
  • Cancer Care
  • Leukemia
  • Lymphoma
  • Neuroblastoma
  • Neutropenia

Research Activities

The children we treat need the most powerful, effective therapies right now – not days, weeks, or months from now. So I’m deeply involved in clinical and translational research, actively seeking to learn as much as possible from each child in our care. Our physicians stay up-to-date on the latest research strategies for kids with cancer, because everything we learn will help others in the future.

The focus of our lab is to identify novel therapies for children with cancer. We recognize the challenges that we face: 1) childhood cancer is a rare and orphan disease; 2) it is difficult to complete clinical trials for rare diseases; 3) drug development is focused on malignancies in adults; 4) we need better treatments for children now. To address all these problems, my lab works with a team of investigators at other institutions around the world to identify those therapies most likely to succeed in children and to prioritize them for clinical development. With more than 60 publications resulting in dozens of clinical trials, we have made great progress. Team science is the model that works. We don’t compete, we cooperate and share.

As a member of the Children’s Oncology Group Scientific Council, Chair of the Myeloid Disease committee, member of the Bone Tumor Committee and member of the Young Investigator Committee, I am in a position to maintain a cutting edge and relevant focus in my lab. We are continually taking results from the bench to bedside and back again; asking those research questions that will have the greatest impact on patient care. Our mission is, simply stated, to find better treatments for childhood cancer. Cure is not impossible with the right teams asking the right questions.

Medical Interests

  • Bone marrow failure systems
  • Graft vs. host disease
  • Retinoblastoma
  • Transplant for inherited disorders
  • Treatment of non-malignant disorders of the bone marrow and immune system

  • English