Takeshi Tsuda, MD

Cardiology

Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Other Offices

Education & Training

Fellowship

  • Other - University of Medicine & Dentistry of New Jersey, 1998
  • Pediatric Cardiology - The Children's Hospital of Philadelphia, 1996
  • Cardiology Research - The Children's Hospital of Philadelphia, 1990

Internship

  • Pediatrics - Milton S. Hershey Medical Center, 1991

Residency

  • Pediatrics - The Children's Hospital of Philadelphia, 1993
  • Shinshu University Medical Center, 1989

Medical/Dental School

  • M.D. - Shinshu University School of Medicine, 1984

Board Certifications

  • American Board of Pediatrics/Pediatric Cardiology

Insurance Accepted

  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/EPO/POS
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas Delaware
  • Amerihealth Caritas Delaware - Delaware & Chester CTY & TJU Sites ONLY
  • Amerihealth Caritas Delaware - Deptford only
  • Carefirst MD Community Health Plan Mcaid
  • Celtic Transplant Network for Ambetter
  • Celtic Transplant Network for Centene
  • Celtic Transplant Network for Delaware First Health
  • Cigna & Great West HMO/POS/EPO
  • Cigna & Great West PPO
  • Cigna Lifesource Transplant
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Delaware First Health
  • Delaware First Health - Concordville & Media Sites ONLY
  • Delaware First Health - Deptford only
  • Delaware Medicaid/Diamond State
  • Delaware Medicaid/Diamond State - Delaware & Chester CTY & TJU Sites ONLY
  • Delaware Medicare
  • Emerging Therapies Transplant
  • Fidelis Care NJ Medicaid HMO
  • First Health PPO
  • First Health/Affordable PPO
  • Geisinger Health Plan Commercial
  • Global Medical Managment DE/PA
  • Global Medical Mangment NJ
  • Health Partners Medicaid/Kidz Partner HMO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Blue Cross Blue Shield of Delaware *PA Loc Contiguous to DE*
  • Highmark Blue Cross Blue Shield of Delaware *PA Loc NONContiguous to DE*
  • Highmark Blue Cross Blue Shield of Pennsylvania
  • Highmark Health Options Medicaid - Deptford only
  • Highmark Medicaid Health Options
  • Highmark Medicaid Health Options - Delaware & Chester CTY & TJU Sites ONLY
  • Horizon Blue Cross Blue Shield of New Jersey
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Independence Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Keystone First CHIP
  • Keystone First Medicaid HMO
  • Maryland Medicaid
  • Maryland Medicaid Chester County ONLY
  • Multiplan PPO
  • New Jersey Medicaid
  • Olympus Managed Healthcare PPO DE/PA
  • Olympus Managed Healthcare PPO NJ
  • Pennsylvania Medicaid
  • Preferred Healthcare PPO
  • Priority Partners John Hopkins
  • Private Health Care Systems (PHCS)
  • Private Healthcare Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Six Degrees Health Transplant
  • Six Degrees Health-Lucent
  • Star Healthcare Network
  • Star Healthcare Network
  • Three Rivers Provider Network
  • Tricare/Humana Military Health Services/CHAMPVA
  • United Healthcare HMO/POS/PPO/EPO
  • UPMC Medicaid/CHIP
  • US Family Health Plan
  • USFHP-John Hopkins
  • Wellpoint Maryland Medcaid
  • Wellpoint Maryland Medicaid - Chester County Only

  • Aortic Stenosis
  • Atrial Septal Defects
  • Atrioventricular Canal Defect
  • Cardiomyopathy
  • Coarctation of the Aorta
  • Congenital Heart Disease
  • Heart Failure
  • Hypoplastic Left Heart Syndrome
  • Interrupted Aortic Arch
  • Patent Ductus Arteriosis
  • Pulmonary Artery Sling
  • Pulmonary Atresia
  • Pulmonary Hypertension
  • Pulmonary Stenosis
  • Tetralogy of Fallot
  • Total Anomalous Pulmonary Venous Return
  • Transposition of the Great Arteries
  • Tricuspid Atresia
  • Truncus Arteriosus
  • Ventricular Septal Defects

  • Unexpected sudden cardiac arrest due to ventricular fibrillation in a 7-year-old boy with Duchenne muscular dystrophy; Cardiology in the Young; (2026).

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  • Creating a Pediatric Cardio-Oncology Clinic for Childhood Cancer Survivors; American Journal of Medical Quality; (2025).

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  • Giant Left Ventricular Aneurysm in a Child After Surgical Repair of Anomalous Left Coronary Artery From the Pulmonary Artery and Subsequent Mitral Valve Replacement; World journal for pediatric & congenital heart surgery; (2025).

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  • Sinus Tachycardia and Unrelieved Wall Stress Precede Left Ventricular Systolic Dysfunction During Preclinical Cardiomyopathic Changes in Duchenne Muscular Dystrophy; Journal of Cardiovascular Development and Disease; (2025).

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  • Aberrant Subclavian Artery in Interrupted Aortic Arch with Severe Aortic Outlet Obstruction: Cerebral Blood Flow as a Possible Determinant of Embryonic Cardiovascular Development?; Pediatric Cardiology; (2024).

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  • Adaptive Growth of the Ductus Arteriosus and Aortic Isthmus in Various Ductus-Dependent Complex Congenital Heart Diseases; Pediatric Cardiology; (2024).

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  • Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults; Current Hypertension Reports; (2024).

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  • Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses; OncoImmunology; (2024).

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  • Coronary microvascular dysfunction in childhood; American Heart Journal Plus: Cardiology Research and Practice; (2024).

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  • Unexpected and atypical clinical presentation of myocardial infarction in infants and children; Cardiology in the Young; (2024).

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  • Cardiopulmonary Exercise Testing Characterizes Silent Cardiovascular Abnormalities in Asymptomatic Pediatric Cancer Survivors; Pediatric Cardiology; (2023).

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  • Efficacy and safety of coronary computed tomography angiography in diagnosing coronary lesions in children; Cardiology in the Young; (2023).

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  • Exercise Testing in Hypertension and Hypertension in Athletes; Pediatric Hypertension; (2023).

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  • Surveillance cardiopulmonary exercise testing can risk-stratify childhood cancer survivors: who are at risk for long-term cardiovascular complications and why?; Unknown Source; (2023).

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  • Surveillance cardiopulmonary exercise testing can risk-stratify childhood cancer survivors; Cardio-Oncology; (2023).

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  • A Combined Analysis of Peak and Submaximal Exercise Parameters in Delineating Underlying Mechanisms of Sex Differences in Healthy Adolescents; Pediatric Cardiology; (2022).

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  • Feeding Difficulty and Poor Somatic Growth After Reparative Cardiac Surgery in Infants with Complex Congenital Heart Disease; Journal of Pediatrics; (2022).

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  • Rapid Growth of Left Atrial Thrombus in a Pediatric Heart Transplant Recipient; Annals of Thoracic Surgery; (2022).

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  • Unexpected sudden cardiac arrest due to ventricular fibrillation in a 7-year-old boy with Duchenne Muscular Dystrophy with advanced myocardial fibrosis; American College of Cardiology Annual Scientific Sessions, Washington, United States, 2/04/22; (2022).

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  • Clinical assessment of ventricular wall stress in understanding compensatory hypertrophic response and maladaptive ventricular remodeling; Journal of Cardiovascular Development and Disease; (2021).

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  • Low-dose prostaglandin E1 is safe and effective for critical congenital heart disease; Cardiology in the Young; (2021).

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  • Early Surgical Closure of Atrial Septal Defect Improves Clinical Status of Symptomatic Young Children with Underlying Pulmonary Abnormalities; Pediatric Cardiology; (2020).

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  • Echocardiographic assessment of mechanical circulatory support and heart transplant; Progress in Pediatric Cardiology; (2020).

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  • Echocardiographic assessment of ventricular function; Progress in Pediatric Cardiology; (2020).

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  • Effective myocardial perfusion and concomitant haemodynamic status determine the clinical diversity of anomalous left coronary artery from the pulmonary artery; Cardiology in the Young; (2020).

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  • Overfeeding and obesity in young children with positive pressure ventilation via tracheostomy following cardiac surgery; Cardiology in the Young; (2020).

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  • Sudden cardiac death in children and young adults without structural heart disease; Reviews in Cardiovascular Medicine; (2020).

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  • Identifying Subclinical Coronary Abnormalities and Silent Myocardial Ischemia After Arterial Switch Operation; Pediatric Cardiology; (2019).

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  • Reply to correspondence article, correspondence on “Significance of automated external defibrillator in identifying lethal ventricular arrhythmias”; European Journal of Pediatrics; (2019).

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  • Significance of automated external defibrillator in identifying lethal ventricular arrhythmias; European Journal of Pediatrics; (2019).

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  • Clinical manifestations and overall management strategies for duchenne muscular dystrophy; Methods in Molecular Biology; (2018).

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  • Development of quality metrics for ambulatory pediatric cardiology; Congenital Heart Disease; (2018).

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  • Extracellular interactions between fibulins and transforming growth factor (TGF)-β in physiological and pathological conditions; International Journal of Molecular Sciences; (2018).

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  • Development of Quality Metrics in Ambulatory Pediatric Cardiology; Journal of the American College of Cardiology; (2017).

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  • Dystrophic cardiomyopathy; Journal of Cardiovascular Development and Disease; (2017).

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  • Management of cardiac involvement associated with neuromuscular diseases; Circulation; (2017).

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  • Fibulin-2 is essential for angiotensin II-induced myocardial fibrosis mediated by transforming growth factor (TGF)-β; Laboratory Investigation; (2016).

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  • Aneurysm development in patients with a bicuspid aortic valve is not associated with transforming growth factor-β activation; Arteriosclerosis, Thrombosis, and Vascular Biology; (2015).

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  • Coronary artery problems late after arterial switch operation for transposition of the great arteries; Circulation Journal; (2015).

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  • Early-progressive dilated cardiomyopathy in a family with Becker muscular dystrophy related to a novel frameshift mutation in the dystrophin gene exon 27; Journal of Human Genetics; (2015).

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  • Acquired discrete subaortic stenosis in solid organ transplant recipients; Pediatric Transplantation; (2014).

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  • Enhanced bioactive myocardial transforming growth factor-β in advanced human heart failure; Circulation Journal; (2014).

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  • Fibulin-2 deficiency attenuates angiotensin II-induced cardiac hypertrophy by reducing transforming growth factor-β signalling; Clinical Science; (2014).

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  • Fibulin-2 is involved in early extracellular matrix development of the outgrowing mouse mammary epithelium.; Cellular and Molecular Life Sciences; (2014).

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  • Reduced fibulin-2 contributes to loss of basement membrane integrity and skin blistering in mice lacking integrin α3β1 in the epidermis; Journal of Investigative Dermatology; (2014).

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  • Integrated wall stress; Journal of Translational Medicine; (2013).

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  • Loss of fibulin-2 protects against progressive ventricular dysfunction after myocardial infarction; Journal of Molecular and Cellular Cardiology; (2012).

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  • Quantification of active and total transforming growth factor-β levels in serum and solid organ tissues by bioassay; BMC Research Notes; (2012).

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  • What we can learn from graduate medical education in the United States; IRYO - Japanese Journal of National Medical Services; (2009).

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  • Assessment by logistic model of hemodynamic changes during general anesthesia; Japanese Journal of Anesthesiology; (2008).

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  • A comparative analysis of the fibulin protein family; Journal of Biological Chemistry; (2007).

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  • An ultrasound imaging method for in vivo tracheal bulk and Young's moduli of elasticity; Journal of Biomechanics; (2007).

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  • Biological Role of Fibulin-2 in Cardiovascular Development; Cardiovascular Development and Congenital Malformations: Molecular & Genetic Mechanisms; (2007).

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  • Gene expression profile of bioreactor-cultured cardiac cells; DNA and Cell Biology; (2007).

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  • Time course of systolic and diastolic blood pressure decreases during the preintubation period of anesthesia induction; Journal of Clinical Anesthesia; (2007).

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  • Fibulins in Development and Heritable Disease; Birth Defects Research Part C - Embryo Today: Reviews; (2004).

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  • Zinc Finger Protein Zac1 Is Expressed in Chondrogenic Sites of the Mouse; Developmental Dynamics; (2004).

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  • Post-ischemic myocardial fibrosis occurs independent of hemodynamic changes; Cardiovascular Research; (2003).

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  • Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development; Anatomical Record; (2003).

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  • Expression and potential role of angiopoietins and Tie-2 in early development of the mouse metanephros; Developmental Dynamics; (2001).

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  • Fibulin-2 expression marks transformed mesenchymal cells in developing cardiac valves, aortic arch vessels, and coronary vessels; Developmental Dynamics; (2001).

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  • Application of plastic embedding for sectioning whole-mount immunostained early vertebrate embryos.; Methods in Molecular Biology; (2000).

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  • Differential expression of flectin in the extracellular matrix and left- right asymmetry in mouse embryonic heart during looping stages; Developmental Genetics; (1998).

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  • Left-right asymmetric localization of flectin in the extracellular matrix during heart looping; Developmental Biology; (1996).

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  • Spatiotemporal localization of flectin in the mouse embryo; FASEB Journal; (1996).

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  • Comprehensive linear and nonlinear heart rate variability normative data in children; Clinical Autonomic Research; (0000).

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  • Diverse Cardiac Phenotype of Becker Muscular Dystrophy; Pediatric Cardiology; (0000).

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  • Japanese