Pasquale Casale, MD


Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Other Offices

Get to Know Me

Pasquale Casale, MD, MHA is a devoted husband and father who dedicated his career to helping children through the field of pediatric urology. He has pioneered many minimally invasive surgeries that were never before performed on children, to allow them to heal faster. He chose pediatric urology because it is multifaceted and deals with important personal issues such as sexuality and continence, as well as painful conditions and malignancies. 

Why I Treat Children

I chose pediatric urology because it is very important to take care of children. We lost our son, and we were devastated. His journey made me realize how precious life is. Children are truly impactful in the world. They play a special component in our lives that sometimes we take for granted. One of the most rewarding parts of being a pediatric urologist is helping children get through issues that sometimes are difficult to openly discuss, as they can be very intimate problems. Some are very social problems that can stop children from normal activities like sleepovers and dating. The problems can pose future issues with relationships and gender identity, so being able to make a difference for those children in such a very personal arena is simply amazing. Therefore, making a difference for them whether it’s surgical or just through counseling or just by holding someone’s hand to tell them that everything is going to be OK is priceless.

What I'm Passionate About

The overall health, well-being and safety of my patients drives me. Decreasing poor outcomes and getting kids back to the business of being kids as soon as possible is paramount to me. Time is precious, so the faster we can have children recover, the more time they will have to develop themselves. I have dedicated my academic career to minimally invasive surgery. It is one of the most exciting things that is happening in pediatric urology. Because of smaller instrumentation and robotic technology, we can do procedures never thought possible to be done in a minimal fashion in kids easily. We can ensure that their healing process is faster. We can also ensure that they get back to their normal activities sooner than with conventional open surgery. We can do this type of surgery with robotics through what we call laparoscopic access, which are incisions the size of a grain of rice. Patients typically go home the next day and I have them going back to full activities within two weeks.  

How I Try to Make A Difference

I made a simple “ABC Rule” of how I care for patients. Availability — my patients always have access to me not only through my office but also through email as well as my cell. I encourage them to reach out any time day or night if they have questions or concerns. I'm there for them. Bonding — Every child I care for becomes part of who I am. My relationship with the patients and families is very important to me. Understanding their perspective and needs will help me give them the safest and most effective, personal care they require to get better. Compassion — One of the most vulnerable times in one's life is when they are seeking medical advice. We, or someone we love, have all experienced that feeling. It can be a scary and helpless time. I believe listening, caring and diligence is the trifecta of patient safety and good care. I am honored to be given the privilege of caring for them and help them get to a healthier life. 

Education & Training


  • Pediatric Urology - University of Washington School of Medicine, 2004


  • Urology - Jefferson Medical College - Residency, 2002

Internship Residency

  • General Surgery - Beth Israel Medical Center, 1998

Medical/Dental School

  • Doctor Of Medicine - Albert Einstein College of Medicine, 1996

Board Certifications

  • American Board of Urology
  • American Board of Urology/Pediatric Urology

Awards & Recognition

  • 2023Super Doctor,
  • 2009–2023Patient’s Choice Award
  • 2005–2023Top Doctors, Castle Connolly
  • 2005–2023Honor Roll, Healthgrades
  • 2005–2023Patients’ Top Choice Award, U.S. News & World Report
  • 2016–2020Top Doctors, New York Metro Area (digital guide)
  • 2014–2019Top Doctors, New York Magazine
  • 2012–2018Samberg Scholar, N.Y. Presbyterian Hospital
  • 2015Top Doctors, New York Metro Area (book series, 18th edition)
  • 2014Top Doctors, New York Metro Area (book series, 17th edition)
  • 2004Fellow Achievement Award, Society of Laparoendoscopic Surgeons
  • 2003Fellow Achievement Award, Society of Laparoendoscopic Surgeons
  • 2002Gerald P. Murphy Scholar Award for Prostate Cancer
  • 2002The Pfizer Scholars in Urology Award
  • 1996Distinction in Research, Reconstructive Surgery

Insurance Accepted

  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/EPO/POS
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas Delaware
  • Carefirst MD Community Health Plan Mcaid
  • Cigna & Great West HMO/POS/EPO
  • Cigna & Great West PPO
  • Cigna Lifesource Transplant
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Delaware First Health
  • Delaware Medicaid/Diamond State
  • Delaware Medicare
  • Devon Health Services
  • Fidelis Care NJ Medicaid HMO
  • First Health PPO
  • First Health/Affordable PPO
  • Geisinger Health Plan Commercial
  • Global Medical Managment DE/PA
  • Global Medical Mangment NJ
  • Health Partners Medicaid/Kidz Partner HMO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Medicaid Health Options
  • Horizon Blue Cross Blue Shield of New Jersey
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Keystone First Medicaid HMO
  • Lifetrac Transplant
  • Maryland Medicaid
  • Multiplan PPO
  • National Transplant (Humana)
  • New Jersey Medicaid
  • Olympus Managed Healthcare PPO DE/PA
  • Olympus Managed Healthcare PPO NJ
  • Pennsylvania Medicaid
  • Preferred Healthcare PPO
  • Private Health Care Systems (PHCS)
  • Private Healthcare Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Star Healthcare Network
  • Star Healthcare Network
  • Three Rivers Provider Network
  • Tricare/Humana Military Health Services
  • United Healthcare of the Mid-Atlantic
  • UPMC Medicaid
  • US Family Health Plan
  • Wellpoint Maryland Medcaid

  • Congenital Hydronephrosis
  • Cryptorchidism
  • Hypospadias
  • Neurogenic Bladder
  • Urinary Stone Disease
  • Vesicoureteral Reflux
  • Voiding Dysfunction

Research Activities

  • Minimally Invasive Surgery
  • Robotic Surgery
  • Endoscopy
  • Laparoscopy
  • Simulation and Training
  • Surgical Device Development Patent Acquisition

Medical Interests

  • Minimally Invasive Surgery
  • Robotic Surgery
  • Endoscopy
  • Laparoscopy
  • Urologic Oncology
  • Renal Transplantation
  • Trauma and Reconstructive Surgery
  • Hydronephrosis
  • Urinary Stone Disease
  • Obstructive Uropathy
  • Vesicoureteral Reflux
  • Fetal Urology

  • English
  • Italian