Matthew D. Di Guglielmo, MD, PhD
Consultative PediatricsPrimary Office
Get to Know Me
I am a Delaware native and grew up in Wilmington. I am married, with two daughters, and come from a family that enjoys music, cooking, and eating. One of the most rewarding parts of my work is when babies I have seen in the nursery, on their first day of life, grow up into active toddlers and children.Why I Treat Children
During my childhood and as an adolescent, I had terrific doctors who were role models, and they inspired me to go into medicine. When I was in medical school, I also had great experiences with the people working in pediatrics. Kids grow so much between birth and college-age. I have always enjoyed caring for children during this rapid-development period.What I'm Passionate About
I was always interested in science and have a strong interest in improving health care outcomes for the children I care for. A lot of this came from my experience with the health care system and members of my own family. My research interests center on improving everyone’s access to quality health care.Education & Training
Internship Residency
- Pediatrics - Nemours/Alfred I. duPont Hospital for Children, 2007
Medical/Dental School
- MD/PhD - Jefferson Medical College, 2004
Board Certifications
- American Board of Pediatrics/General Pediatrics
Awards & Recognition
- 2014 Delaware Today magazine, Top Doctors
Insurance Accepted
- Aetna Better Health PA Kids HMO
- Aetna HMO
- Aetna PPO/POS/EPO
- Amerihealth Caritas Delaware
- Carefirst MD Community Health Plan Mcaid
- Cigna Lifesource Transplant
- Cigna/Great West HMO EPO POS
- Cigna/Great West PPO
- Delaware First Health
- Delaware Medicaid/Diamond State
- Delaware Medicare
- Devon Health Services
- Fidelis Care NJ Medicaid HMO
- First Health/Affordable PPO
- Geisinger Health Plan Commercial
- Global Medical Managment DE/PA
- Health Partners Medicaid/Kidz Partner HMO
- Highmark Blue Cross Blue Shield Delaware HMO POS EPO
- Highmark Blue Cross Blue Shield Delaware PPO
- Highmark Blue Cross Blue Shield Delaware Traditional
- Highmark Blue Cross Blue Shield Delware HMO PPO POS EPO
- Highmark Medicaid Health Options
- Horizon Blue Cross and Blue Shield NJ HMO
- Horizon Blue Cross and Blue Shield of NJ PPO
- IBC AMERIHEALTH KEYSTONE HMO/PPO PCP DE
- IBC AMERIHEALTH KEYSTONE HMO/PPO PCP PA
- Independence Blue Cross/Amerihealth/Keystone HMO PPO
- Insurance Administrators of America
- INTEGRA Administrative Group (ClaimsBridge)
- Keystone First Medicaid HMO
- Lifetrac Transplant
- Maryland Medicaid
- Multiplan PPO
- National Transplant (Humana)
- New Jersey Medicaid
- Olympus Managed Healthcare PPO DE/PA
- Pennsylvania Medicaid
- Plan Vista/NPPN PPO
- Preferred Healthcare PPO
- Private Health Care Systems (PHCS)
- Qualcare HMO/POS/PPO
- Star Healthcare Network
- Three Rivers Provider Network
- Tricare/Humana Military Health Services
- United Healthcare of the Mid-Atlantic
- UPMC MCAID/CHIP PA DE
- US Family Health Plan
- Wellpoint Maryland Medicaid
Medical Interests
- Access to health care
- Education of new parents and caregivers
- Healthy growth and development
- Improving nutrition and food choices
- Newborn care
- Translational medicine
- Utilization of health care services
- Vaccines and public health
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The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity; Pediatric Gastroenterology, Hepatology & Nutrition; (2021).
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Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity; Pediatric and Developmental Pathology; (2018).
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A Pilot Study Measuring The Novel Satiety Hormone, Pro-Uroguanylin, In Adolescents With And Without Obesity; Journal of Pediatric Gastroenterology and Nutrition; (2017).
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General Pediatrician-Staffed Behavioral/Developmental Access Clinic Decreases Time to Evaluation of Early Childhood Developmental Disorders; Journal of Developmental and Behavioral Pediatrics; (2017).
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Pediatrician preferences, local resources, and economic factors influence referral to a subspecialty access clinic; Primary Health Care Research and Development; (2016).
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Female Adolescent Presenting With Abdominal Pain: Accidental Wire Bristle Ingestion Leading to Colonic Perforation; Pediatric Emergency Care; (2015).
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A new model to decrease time-to-appointment wait for gastroenterology evaluation; Pediatrics; (2013).
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Aortic pseudoaneurysm in a child with a left mainstem bronchial stent; Pediatric Critical Care Medicine; (2008).
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Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C; FEBS Letters; (2001).
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Guanylyl cyclase C (GC-C) inhibits human colon carcinoma cell growth; Clinical Pharmacology and Therapeutics; (2001).
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Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells; Proceedings of the National Academy of Sciences of the United States of America; (2001).
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- English