Cancer Biomarkers & Therapeutics Publications


Cardonick EH, Gringlas MB, Hunter K, Greenspan J. Development of children born to mothers with cancer during pregnancy: comparing in utero chemotherapy-exposed children with nonexposed controls. Am J Obstet Gynecol 2015;212:658.


Knoble N, Alderfer MA, Hossain MJ. Socioeconomic status and childhood acute myeloid leukemia mortality risk: analysis of SEER data. Cancer Epidemiol 2016;44:101-108.


Kurmasheva RT, Gorlick R, Kolb EA, Keir ST, Maris JM, Lock RB, Carol H, Kang M, Reynolds CP, Wu J, Houghton PJ, Smith MA. Initial testing of VS-4718, a novel inhibitor of focal adhesion kinase (FAK), against pediatric tumor models by the pediatric preclinical testing program. Pediatr Blood Cancer 2016 Oct 27 [Epub ahead of print].


Lee SJ, Li Z, Litan A, Yoo S, Langhans SA. EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation. BMC Cell Biol 2015;16:24.


Li Z, Langhans SA. Regulation of Na,K-ATPase in epithelial-mesenchymal transition and cancer. In: Chakraborti S, Naranjan S, eds. Regulation of Membrane Na+-K+-ATPase: Advances in Biochemistry in Health and Disease. New York, NY: Springer; 2016:375-388.


Lock R, Carol H, Maris JM, Kolb EA, Gorlick R, Reynolds CP, Kang MH, Keir ST, Wu J, Purmal A, Gudkov A, Kurmashev D, Kurmasheva RT, Houghton PJ, Smith MA. Initial testing (stage 1) of the curaxin CBL0137 by the pediatric preclinical testing program. Pediatr Blood Cancer 2016 Sep 21 [Epub ahead of print].


Maxson JE, Ries RE, Wang YC, Gerbing RB, Kolb EA, Thompson SL, Guidry Auvil JM, Marra MA, Ma Y, Zong Z, Mungall AJ, Moore R, Long W, Gesuwan P, Davidsen TM, Hermida LC, Hughes SB, Farrar JE, Radich JP, Smith MA, Gerhard DS, Gamis AS, Alonzo TA, Meshinchi S. CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML. Blood 2016;127:3094-3098.


Moodalbail DG, Apple LZ, Meyers KE, Ginsberg JP, Kaplan BS, Bellah R. Acquired multiple cysts of the kidney in neuroblastoma survivors. Am J Kidney Dis 2016;68:134-137.


Murphy B, Yin H, Maris JM, Kolb EA, Gorlick R, Reynolds CP, Kang MH, Keir ST, Kurmasheva RT, Dvorchik I, Wu J, Billups CA, Boateng N, Smith MA, Lock RB, Houghton PJ. Evaluation of alternative in vivo drug screening methodology: a single mouse analysis. Cancer Res 2016;76:5798-5809.


Nagasubramanian R, Wei J, Gordon P, Rastatter JC, Cox MC, Pappo A. Infantile fibrosarcoma with NTRK3-ETV6 fusion successfully treated with the tropomyosin-related kinase inhibitor LOXO-101. Pediatr Blood Cancer 2016;63:1468-1470.


Petty LA, Sokol EA, Bartlett AH, McNeer JL, Alexander KA, Pisano J. Repeated blood cultures in pediatric febrile neutropenia: would following the guidelines alter the outcome? Pediatr Blood Cancer 2016;63:1244-1249.


Quillen J, Bradley H, Calamaro C. Identifying barriers among childhood cancer survivors transitioning to adult health care. J Pediatr Oncol Nurs 2016 Mar 11 [Epub ahead of print].


Rohan JM, Fukuda T, Alderfer MA, Wetherington Donewar C, Ewing L, Katz ER, Muriel AC, Vinks AA, Drotar D. Measuring medication adherence in pediatric cancer: an approach to validation. J Pediatr Psychol 2016 May 16 [Epub ahead of print].


Roth M, Barris DM, Piperdi S, Kuo V, Everts S, Geller D, Houghton P, Kolb EA, Hawthorne T, Gill J, Gorlick R. Targeting glycoprotein NMB with antibody-drug conjugate, glembatumumab vedotin, for the treatment of osteosarcoma. Pediatr Blood Cancer 2016;63:32-38.


Sampson VB, Vetter NS, Zhang W, Patil PU, Mason RW, George E, Gorlick R, Kolb EA. Integrating mechanisms of response and resistance against the tubulin binding agent eribulin in preclinical models of osteosarcoma. Oncotarget 2016 Nov 15 [Epub ahead of print].


Samson K, Rourke MT, Alderfer MA. A qualitative analysis of the impact of childhood cancer on the lives of siblings at school in extra-curricular activities and with friends. Clin Pract Pediatr Psychol 2016 Dec [Epub ahead of print].


Santos S, Crespo C, Canavarro MC, Alderfer MA, Kazak AE. Family rituals, financial burden, and mothers' adjustment in pediatric cancer. J Fam Psychol 2016 Sep 12 [Epub ahead of print].


Soori M, Lu G, Mason RW. Cathepsin inhibition prevents autophagic protein turnover and downregulates insulin growth factor-1 receptor-mediated signaling in neuroblastoma. J Pharmacol Exp Ther 2016;356:375-386.


Sun JE, Stewart B, Litan A, Lee SJ, Schneider JP, Langhans SA, Pochan DJ. Sustained release of active chemotherapeutics from injectable-solid beta-hairpin peptide hydrogel. Biomater Sci 2016;4:839-848.


Van Schoors M, Caes L, Alderfer MA, Goubert L, Verhofstadt L. Couple functioning after pediatric cancer diagnosis: a systematic review. 2016 Jun 27 [Epub ahead of print].



Alderfer M, Stanley C, Conroy R, Long K, Fairclough D, Kazak A, Noll B. The social functioning of siblings of children with cancer: a multi-informant investigation. J Pediatr Psychol 2015;40:309-319.


Alderfer MA, Zelley K, Lindell RB, Novokmet A, Mai PL, Garber JE, Nathan D, Scollon S, Chun NM, Patenaude AF, Ford JM, Plon SE, Schiffman JD, Diller LR, Savage SA, Malkin D, Ford CA, Nichols K. Parent decision-making around the genetic testing of their children for germline TP53 mutations. Cancer 2015;121:286-293.


Andreoli SM, Kazahaya K. Pediatric nasal tumors. In: Sataloff R, Hartnick C, eds. Sataloff’s Comprehensive Textbook of Otolaryngology. Jaypee Medical Publishers: Philadelphia. 2015;353-360.


Attia MW. Neck masses. In: Selbst SM, ed. Pediatric Emergency Medicine Secrets, 3rd edn. WB Saunders: Philadelphia. 2015;143-149.


Balasubramaniam SL, Gopalakrishnapillai A, Barwe SP. Ion-dependency of Na,K-ATPase mediated epithelial cell adhesion and migration. Am J Physiol Cell Physiol 2015;309:C437-C441.


Balasubramaniam SL, Gopalakrishnapillai A, Gangadharan V, Duncan RL, Barwe SP. Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling. J Biol Chem 2015;290:12463-12473.


Bradfield SM, Sandler E, Geller T, Tamura RN, Krischer JP. Glutamic acid is not beneficial for the prevention of vincristine neurotoxicity in children with cancer. Pediatr Blood Cancer 2015;62:1004-1010.


Brier M, Schwartz L, Kazak A. Systematic review of psychosocial and health-promotion interventions for survivors of childhood cancer. Health Psychol 2015;34:130-148.


Buchbinder D, Oeffinger K, Franco-Villalobos C, Yasai Y, Alderfer MA, Armstrong GT, Casillas J, Ford J, Krull K, Leisenring W, Recklitis C, Robison LL, Zeltzer L, Lown EA. Tobacco use among siblings of childhood cancer survivors: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer 2015 Aug 25 [Epub ahead of print].


Gopalakrishnapillai A, Kolb EA, Dhanan P, Mason RW, Napper A, Barwe SP. Disruption of annexin II/p11 interaction suppresses leukemia cell binding, homing, and engraftment and sensitizes leukemia cells to chemotherapy. PLOS One 2015;10:e0140564.


Hocking M, McCurdy M, Turner E, Kazak A, Noll R, Phillips P, Barakat L. Social competence in pediatric brain tumor survivors: application of a heuristic model from social neuroscience and developmental psychology. Pediatr Blood Cancer 2015;62:375-384.


Hossain MJ, Xie L, Caywood EH. Prognostic factors of childhood and adolescent acute myeloid leukemia (AML) survival: evidence from four decades of US population data. Cancer Epidemiol 2015;39:720-726.


Hossain MJ, Xie L. Sex disparity in childhood and young adult acute myeloid leukemia (AML) survival: evidence from US population data. Cancer Epidemiol 2015;39:892-900.


Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward S, Damoiseuax R, Rajasekaran AK. Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta1-subunit expression. PLOS One 2015;10:e0122442.


Khaja WA, Pogrebniak AE, Bolling JP. Combined orbital proptosis and exudative retinal detachment as initial manifestations of acute myeloid leukemia. JAAPOS 2015;19:479-482.


King AA, Kamani N, Bunin N, Sahdev I, Brochstein J, Hayashi RJ, Grimley M, Abraham A, Dioguardi J, Wah Chan K, Douglas D, Adams R, Andreansky M, Anderson E, Gilman A, Chaudhury S, Yu L, Dalal J, Hale G, Cuvelier G, Jain A, Krajewski J, Gillio A, Kasow KA, Delgado D, Hanson E, Murray L, Shenoy S. Successful matched sibling donor marrow transplantation following reduced intensity conditioning in children with hemoglobinopathies. Am J Hematol 2015 Sep 8 [Epub ahead of print].


Kolb EA, Sampson V, Stabley D, Walter A, Sol-Church K, Cripe T, Hingorani P, Ahern CH, Weigel BJ, Zwiebel J, Blaney SM. A phase I trial and viral clearance study of reovirus (Reolysin) in children with relapsed or refractory extra-cranial solid tumors: a Children's Oncology Group Phase I Consortium report. Pediatr Blood Cancer 2015;62:751-758.


Lee SJ, Li Z, Litan A, Yoo S, Langhans SA. EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation. BMC Cell Biol 2015;16:24-25.


Lee SJ, Litan A, Li Z, Graves B, Lindsey S, Barwe SP, Langhans SA. Na,K-ATPase beta1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer 2015;19:159-160.


Lindsey S, Langhans SA. Epidermal growth factor signaling in transformed cells. Int Rev Cell Mol Biol 2015;5:314:1-41.


Lindsey S, Piatt JH, Worthington P, Sonmez C, Sathaye S, Schneider JP, Pochan DJ, Langhans SA. Beta hairpin peptide hydrogels as an injectable solid vehicle for neurotrophic growth factor delivery. Biomacromolecules 2015;14:2672-2683.


Litan A, Langhans SA. Cancer as a channelopathy: ion channels and pumps in tumor development and progression. Front Cell Neurosci 2015;9:86-87.


Long KA, Goldish M, Lown EA, Ostrowski N, Alderfer MA, Marsland A, Ring S, Skala S, Ewing L. Major lessons learned from a nationally based community-academic partnership: addressing sibling adjustment to childhood cancer. Families Syst Health 2015;33:61-67.


Reuschel EL, Wang J, Shivers DK, Muthumani K, Weiner DB, Ma Z, Finkel TH. REDD1 is essential for optimal T cell proliferation and survival. PLoS One 2015;10:e0136323.


Rohan J, Drotar D, Alderfer MA, Donewar C, Ewing L, Katz E, Muriel A. Electronic monitoring of medication adherence in early maintenance phase treatment for pediatric leukemia and lymphoma: identifying patterns of nonadherence. J Pediatr Psychol 2015;40:75-84.


Sampson VB, Yoo S, Kumar A, Vetter N, Kolb EA. MicroRNAs and potential targets in osteosarcoma. Front Pediatr 2015;3:69-70.


Santos S, Crespo C, Canavarro MC, Kazak A. Family rituals, cohesion and hope in pediatric cancer quality of life. J Pediatr Psychol 2015;40:664-671.


Van Schoors M, Caes L, Verhofstadt LL, Goubert L, Alderfer MA. Systematic review: family resilience after pediatric cancer diagnosis. J Pediatr Psychol 2015;40:856-868.


Westra SJ, Thacker PG, Podberesky DJ, Lee EY, Iyer RS, Hegde SV, Guillerman RP, Mahani MG. The incidental pulmonary nodule in a child. Part 2: Recommendations from the SPR Thoracic Imaging Committee regarding characterization, significance and follow-up. Pediatr Radiol 2015;45:634-639.


Wiener L, Reader SK, Kazak AE. Special considerations in working with families. In: Wiener L, Pao M, Kazak AE, Kupst MJ, Patenaude AF, eds. Quick Reference for Pediatric Oncology Clinicians: The Psychiatric and Psychological Dimensions of Pediatric Cancer Symptom Management, 2nd edn. New York: Oxford University Press. 2015;271-279.


Worthington P, Pochan DJ, Langhans SA. Peptide hydrogels: versatile matrices for 3D cell culture in cancer medicine. Front Oncol 2015;5:92-93.


Zucker EJ, Epelman M, Newman B. Perinatal thoracic mass lesions: pre- and postnatal imaging. Semin Ultrasound CT MR 2015;36:501-521.




Di Pentima MC, Chan S, Powell J, Napoli JA, Walter AW, Walsh TJ. Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: case report and review. J Pediatr Hematol Oncol 2014;36:e468-70.


Doshi K, Kazak A, Hocking M, DeRosa B, Schwartz L, Hobbie W, Ginsberg J, Deatrick J. Why mothers accompany adolescent and young adult childhood cancer survivors to follow-up clinic visits. J Pediatr Oncol Nurs 2014;31:51-7.


Glickman JF, Lundback T, Napper AD, Niles WD, Simeonov A, Weaver CD, Yin HH, Zaman GJ, Osada H. Controversies in assay and drug development technologies: a focus on assessing irreproducibility. Assay Drug Develop Technol 2014;12:443-51.


Helton KJ, Adams RJ, Kesler KL, Lockhart A, Aygun B, Driscoll C, Heeney MM, Jackson SM, Krishnamurti L, Miller ST, Sarnaik SA, Schultz WH, Ware RE; SWiTCH Investigators (Nagasubramanian R). Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial. Blood. 2014 Aug 7;124(6):891-8.


Hildenbrand A, Alderfer MA, Deatrick J, Marsac M. A mixed-methods assessment of coping with pediatric cancer. J Psychosoc Oncol 2014;32:37-58.


Hocking MC, Kazak A, Schneider S, Barkman D, Barakat L, Deatrick J. Parent perspectives on family-based psychosocial interventions in pediatric cancer: a mixed-methods approach. Support Care Cancer 2014;22:1287-94.


Hossain MJ, Xie L, McCahan SM. Characterization of pediatric acute lymphoblastic leukemia survival patterns by age at diagnosis. J Cancer Epidemiol 2014 Sep 17 [Epub ahead of print]


Hossain MJ, Xie L. Interaction of sex with age at diagnosis and radiation therapy in the survival of pediatric acute lymphoblastic leukemia. J Public Health Epidemiol 2014;6:262-70.


Lindsey S, Langhans SA Crosstalk of oncogenic signaling pathways in transformed cells. Front Oncol 2014;4:1-10.


Patel P, Suzuki Y, Tanaka A, Yabe H, Kato S, Shimada T, Mason RW, Orii KE, Fukao T, Orii T, Tomatsu S. Impact of enzyme replacement therapy and hematopoietic stem cell therapy on growth in patients with Hunter syndrome. Mol Genet Metab Rep 2014;1:184-96.


Patel P, Suzuki Y, Maeda M, Yasuda E, Shimada T, Orii KE, Orii T, Tomatsu S. Growth charts for patients with Hunter syndrome. Mol Genet Metab Rep 2014;1:5-18.


Pelletier W, Hinds P, Alderfer MA, Fairclough D, Stegenga K, Pentz R. Themes reported by families as important when proceeding with pediatric hematopoietic stem cell transplantation. Pediatr Blood Cancer 2014;61:1625-31. Pentz R, Alderfer MA, Pelletier W, Stegenga K, Haight A, Hendershot K, Dixon M, Fairclough D, Hinds P. Concerns and unmet needs of siblings of children undergoing a hematopoietic stem cell transplant: do they need an independent advocate? Pediatrics 2014;133:e1156-e1162


Quinn GP, Vadaparampil ST, Johns T, Alexander KA, Giuliano AR. Adolescent sexual activity and cancer risk: physicians' duty to inform? Current Med Res Opin 2014;3:1827-31.


Rhodes MM, Bates DG, Andrews T, Adkins L, Thornton J, Denham JM. Abdominal pain in children with sickle cell disease. J Clin Gastroenterol 2014;48:99-105.


Wiener L, Pao M, Kazak A, Kupst MJ, Patenaude A. Pediatric Psycho-oncology: A Quick Reference on the Psychosocial Dimensions of Cancer Symptom Management. Oxford University Press: New York. 2014.


Williams PW, Brown KB, Westmoreland T, Herrington B, Sawaya DE, Rezeanu L, Nowicki MJ. Gastric metastasis from an alveolar soft part sarcoma in a child: case report and review of the literature. J Pediatr Hematol Oncol 2014;36:e173-6.


Wolle D, Lee SJ, Li Z, Litan A, Barwe SP, Langhans SA. Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma. Cancer Med 2014;3:1146-58.


Wray L, Vujkovic M, McWilliams T, Cannon S, Devidas M, Stork L, Aplenc R. TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 2014;61:2086-8.


Yan J, Tingey C, Lyde R, Gorham T, Choo D, Muthumani A, Myles D, Weinder L, Kraynyak K, Reuschel E, Finkel TH, Kim JJ, Sardesai N, Ugen K, Muthumani K, Weiner DB. Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model. Cancer Gene Therapy 2014;21:507-17.


Zhang M, Ma Z, Selliah N, Weiss G, Genin A, Finkel TH, Cron RQ. The impact of nucleofection on the activation state of primary human CD4 T cells. J Immunologic Method 2014;408:123-31.


Zucker EJ, Epelman M, Restrepo R, Lee EY. Congenital and acquired large-airway disorders in pediatric patients. In: Garcia-Pena P, Guillerman RP, eds. Pediatric Chest Imaging. 3rd edn. Springer-Verlag: Berlin/Heidelberg. 2014; 219-40.