Floyd R. Livingston, MD
PulmonologyInsurance Accepted
- Aetna Better Health FL Medicaid and Healthy Kids
- Aetna HMO/POS/PPO/EPO
- Alabama Medicaid/Patient First
- AmeriGroup GA MCAID HMO JAX/GA
- AmeriGroup GA PeachCare For Kids Jax/GA
- AvMed
- Blue Cross and Blue Shield HMO
- Blue Cross and Blue Shield Non HMO
- Blue Cross Blue Shield Florida Blue Select
- Cigna PPO/EPO/HMO/POS/OPEN ACCESS
- Community Care Plan Medicaid
- Employers Health Network PPO
- Evolutions Healthcare
- First Health Aetna PPO/EPO
- Florida Community Care
- Florida Medicaid
- Florida Medicare
- Georgia Medicaid/Georgia Better Health/Peachcare
- Health First Health Plans
- HealthSmart Health Plans PPO
- HUMANA HEALTHY HORIZONS (FKA HUMANA MEDICAID)
- Molina Healthcare Medicaid
- Multiplan PPO
- Olympus Managed Healthcare PPO ORL
- Prime Health Services PPO Specialty Florida
- Seminole Tribe of Florida
- Simply Healthcare Healthy Kids
- Simply Healthcare Medicaid HMO
- Star Healthcare Network
- Sunshine SMI/CMS 19 & 21
- Sunshine State Health Plan Medicaid
- Three Rivers Provider Network
- Tricare/Humana Military Health Services/CHAMPVA
- United Healthcare Commercial Products
- United Healthcare Community Plan Medicaid
- Volusia Health Network PPO/EPO
- Apnea
- Asthma
- Cystic Fibrosis
- Sleep Disorders
Research Activities
As Director of Pediatric Pulmonology for Nemours Children's Hospital in Orlando, I oversee all clinical and research functions for the Pulmonary Division and am responsible for research partnerships and collaborative initiatives with other sub-specialties and sponsors. I also have expertise in basic, clinical, and translational research in Cystic Fibrosis, Asthma, Sleep Medicine, Arousal and Ventilatory Responses, Oxidative Stress, and Alveolar Macrophage function. I have published collaboratively on several papers in the American Review of Respiratory Disease, Archives Biochemistry & Biophysics, Pediatric Pulmonology, American Journal of Respiratory Cell and Molecular Biology, Journal of Applied Physiology, Free Radical Biology & Medicine, Chest, Pediatrics, and the New England Journal of Medicine. Currently, my research interests are in Cystic Fibrosis Therapeutics, Pediatric Asthma Outcomes, Asthma Genomics, and Inflammatory Response in Pediatric Obstructive Sleep Apnea.
Our Nemours Aerosol Research Laboratory in Orlando was founded in 1999 to evaluate delivery of inhaled therapies. The delivery of drugs directly to the lungs by the inhaled route improves efficacy and reduces side effects for treatment of lung diseases such as cystic fibrosis (CF). Many of the new drugs are for treatment of CF lung disease. The CF Foundation estimates that there are more than two-dozen new drugs in development for the disease, and many require inhalation. Some of the new drug entities include inhaled antibiotics, airway wetting and clearance agents, long-acting bronchodilators, antioxidants, gene-modifying agents, and gene replacement therapy. With so many treatments for CF requiring inhalation, the time-burden on the patient is so great that non-adherence with therapy becomes a real problem. Therefore, this laboratory explores efficient new technologies to shorten treatment times and participates in clinical research projects designed to improve treatment adherence and study new therapies.
Nemours Orlando is in a unique position to advance the progress in inhaled drug development. Researchers have the capability of testing various drugs and delivery devices in the lab and have the clinical population and experience to carry that research forward into phase 1 through phase 3 testing. The unique strategy employed by the Aerosol Lab for clinical trials has led to success in enrollment and has allowed investigators to participate in the data analysis and present the data from multicenter trials both at meetings and in publications. The Lab opens up new avenues for patients to experience cutting-edge therapies and gives them hope for a better tomorrow. It also has allowed Nemours to participate on a national and international level to affect the care of children with CF and respiratory diseases.
-
What Are the Different Kinds of Apnea?; Curbside Consultation in Pediatric Sleep Disorders 49 Clinical Questions; (2024).
View Full Publication -
What Are the Different Stages of Sleep?; Curbside Consultation in Pediatric Sleep Disorders 49 Clinical Questions; (2024).
View Full Publication -
What is a Circadian Rhythm?; Curbside Consultation in Pediatric Sleep Disorders 49 Clinical Questions; (2024).
View Full Publication -
Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials; Lancet Respiratory Medicine; (2023).
View Full Publication -
Clinical Findings in Adolescents Hospitalized With EVALI; Novel Report on Coagulopathy; Hospital Pediatrics; (2022).
View Full Publication -
Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial; Thorax; (2022).
View Full Publication -
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial; Lancet; (2019).
View Full Publication -
Fish oil supplementation in overweight/obese patients with uncontrolled asthma a randomized trial; Annals of the American Thoracic Society; (2019).
View Full Publication -
Effects of an antioxidant-enriched multivitamin in cystic fibrosis; American Journal of Respiratory and Critical Care Medicine; (2018).
View Full Publication -
Efficacy and safety of lumacaftor and ivacaftor in patients aged 6–11 years with cystic fibrosis homozygous for F508del-CFTR: a randomised, placebo-controlled phase 3 trial; Lancet Respiratory Medicine; (2017).
View Full Publication -
Household proximity to water and nontuberculous mycobacteria in children with cystic fibrosis; Pediatric Pulmonology; (2017).
View Full Publication -
Forced Expiratory Volume in 1 Second Variability Helps Identify Patients with Cystic Fibrosis at Risk of Greater Loss of Lung Function; Journal of Pediatrics; (2016).
View Full Publication -
Hypercapnic arousal responses in Prader-Willi syndrome; Chest; (1995).
View Full Publication -
Modulation of the alveolar macrophage respiratory burst by hydroperoxides; Free Radical Biology and Medicine; (1995).
View Full Publication -
Hypoxic and hypercapnic ventilatory responses in Prader-Willi syndrome; Journal of Applied Physiology; (1994).
View Full Publication -
Stimulation of the rat alveolar macrophage respiratory burst by extracellular adenine nucleotides; Am J Respir Cell Mol Biol; (1993).
View Full Publication -
Sublethal oxidant stress induces a reversible increase in intracellular calcium dependent on NAD(P)H oxidation in rat alveolar macrophages; Archives of Biochemistry and Biophysics; (1992).
View Full Publication -
Hypercapnic and hypoxic ventilatory responses in parents and siblings of children with congenital central hypoventilation syndrome; American Review of Respiratory Disease; (1991).
View Full Publication -
STIRLING MODULE DEVELOPMENT OVERVIEW.; JPL Publication; (1984).
View Full Publication -
SATELLITE POWER SYSTEM (SPS) ENVIRONMENTAL IMPACTS ASSESSMENT.; Los Angeles Counc Eng Sci Proc Ser; (1978).
View Full Publication -
Relaxation distance and equilibrium electron density measurements in hydrogen-helium plasmas; AIAA Journal; (1976).
View Full Publication -
TOWARD UNDERSTANDING THE CONICAL ARC-CHAMBER DRIVER.; undefined; (1973).
View Full Publication -
Planetary entry body heating rate measurements in air and Venus atmospheric gas up to T = 15,000°K; AIAA Journal; (1971).
View Full Publication
- English
- Spanish