Skull Base Surgery Program

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Skull Base Surgery Program

Experienced Experts in Precise Operations


Surgeons with our Skull Base Surgery program discuss young patient's condition.

Skull base surgery is an operation that’s done to take out a tumor or other growth at the base, or bottom, of the skull. Minimally invasive skull base surgery (also called “endoscopic cranial base surgery”) is a surgical technique that lets doctors do this operation through the nose. That means they don’t need to make large cuts outside the body. Instead, the surgeon puts a thin tube with a light and high-definition camera (called an “endoscope”) in the nose. Then, the surgeon uses special tools to remove the tumor or other growth.

Our Nemours specialists are also professors at the Sidney Kimmel Medical College at Thomas Jefferson University. That means our experts are helping to teach the experts of tomorrow. The skull base team at Thomas Jefferson University Hospital (TJU) are also our partners — and they're leaders in making the minimally invasive skull base surgical technique better for kids. In fact, TJU’s skull base experts created many of the techniques and invented instruments used for this cutting-edge operation. TJU’s most well-known skull base surgeons work side-by-side with our Nemours specialists to offer a unique approach for children with rare problems of the skull base and sinuses (the moist air spaces within the bones of the face around the nose).

Together, our Nemours Minimally Invasive Endoscopic Cranial Base Surgery Program helps kids get better faster. Children tend to have less pain, no scars, fewer complications, and less chance of damage to other parts of the brain.

Learn More About Skull Base Surgery

Conditions We Treat

Conditions We Treat


The conditions we treat with skull base surgery include:

  • aneurysmal bone cysts (a noncancerous growth in the bone)
  • cerebrospinal fluid leaks (when there’s a leak of the clear, colorless liquid that delivers nutrients to the brain and spinal cord and “cushions” them for protection)
  • chordomas (tumors along the spine)
  • craniopharyngiomas (brain tumors near the pituitary gland, a tiny organ at the bottom of the brain that makes hormones that regulate growth and reproduction)
  • encephaloceles (when the brain has a hernia — an opening or weakness in the wall of a muscle, tissue or membrane that normally holds an organ in place)
  • fibro-osseous lesions (a group of growths on the jaws, face or skull that are made up of tissues that are hard like bones)
  • juvenile nasopharyngeal angiofibromas (noncancerous tumors in preteen and teen boys’ nasopharynx, where the airways in the nose and mouth meet)
  • meningiomas (tumors on the lining of the brain)
  • meningoceles (when the spinal canal — the area that contains the spinal cord — isn’t fully formed)
  • pituitary tumors (tumors on the pituitary gland)
  • sarcomas (cancers of the connective tissue, which hold the body’s tissues and organs together)
  • teratomas (tumors that may be made up of things like teeth, bone, muscle and hair; includes dermoid tumors — when a baby is born with this kind of growth on the skin, often near the eye)
Services We Offer

Services We Offer


Caring for children with tumors and other conditions that need skull base surgery takes a team of specialists. Depending on your child’s condition, your care team may include doctors and services in:

To get ready for surgery, doctors may order a computed axial tomography (CAT or CT) scan or magnetic resonance imaging (MRI). A CAT scan uses a special doughnut-shaped X-ray machine to provide detailed views of the body. An MRI is also a large doughnut-shaped scanner with a tunnel in the center that uses a magnetic field and sound waves to give detailed images. Your child also may need other tests, treatments and exams before surgery.

Why Choose Us

Why Choose Us


Skull base operations used to require large incisions (cuts). Now we can do these procedures using smaller, hidden cuts or by going through natural openings like the nose. At the Nemours Minimally Invasive Endoscopic Cranial Base Surgery Program, we use advanced equipment and computer navigation systems to make the surgery as precise as possible.

Regional Skull Base Surgery Highlights
U.S.News & World Report Best Children’s Hospitals: Ranked in 7 Specialties.

Our Nemours Minimally Invasive Endoscopic Cranial Base Surgery Program is available at Nemours/Alfred I. duPont Hospital for Children (Wilmington, Del.).

  • ranked one of the nation’s best children’s hospitals for select specialties 
  • board-certified doctors often named among the Best Doctors in America®
  • the largest pediatric interventional radiology program in the country (with teams in the Delaware Valley and Florida)
  • huge pediatric cancer network, with research programs known around the world
  • play therapy sessions to lessen kids’ fears about a procedure
  • Ronald McDonald House of Delaware , right across from our campus, for an affordable home away from home during long hospital stays
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Scheduled Specialist Online Visits

Nemours now offers scheduled specialist appointments through live video chat. Ask your doctor if this is an option for your family.

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Research & Clinical Trials

At Nemours, we’re actively researching new approaches for childhood disease prevention, diagnosis and treatment.

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KidsHealth Library

Learn more about your child’s medical condition from the experts at Nemours’ KidsHealth.