Hemolytic Anemia

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Hemolytic Anemia


Recognized Research and Care for Anemia


Young girl talking to doctor about hemolytic anemia at Nemours.

When the body destroys red blood cells (a process called hemolysis) too fast, our bone marrow increases production. But if those are also destroyed too fast, a child develops hemolytic anemia. Anemia in children is not a disease — it’s a symptom of an underlying condition. “Intrinsic” hemolytic anemia is caused by something a child is born with like sickle cell disease. “Extrinsic” or autoimmune hemolytic anemia can be caused by an illness or from cancer treatment.

Our renowned hematologists (blood disorder specialists) in the Nemours Center for Cancer and Blood Disorders are highly experienced at treating all types of hemolytic anemia. So whether your child’s anemia is the result of a short-term illness, or your family needs to learn the skills to manage a lifelong condition — we’re here to offer the expert care and support you need.

Learn More About Hemolytic Anemia

Types of Hemolytic Anemia We Treat

Types of Hemolytic Anemia We Treat


We see a full spectrum of conditions — far too many to list here. The conditions we treat vary depending on the location and providers selected. Don’t see a condition listed? Call us.

  • autoimmune hemolytic anemia 
  • glucose-6-phosphate dehydrogenase deficiency or “G6PD deficiency”
  • hereditary spherocytosis 
  • pyruvate kinase deficiency or “PK deficiency” 
  • sickle cell disease (also called “sickle cell anemia”)
  • thalassemia (also called “Cooley anemia”) 
Services We Offer for Hemolytic Anemia

Services We Offer for Hemolytic Anemia


We offer a variety of diagnostic and treatment services, which may vary depending on the condition or location, including:

  • antibiotics and medications to treat infections or conditions causing the anemia
  • bone marrow aspiration and biopsy to diagnose the cause of the anemia
  • genetic counseling since some syndromes are inherited
  • immunosuppressive therapy to keep the immune system from attacking healthy cells
  • integrative medicine uses non-medical therapies such as massage, yoga, water therapy
  • intravenous immunoglobulin or IVIG is added to strengthen the immune system
  • nutrition plans from registered dietitians specially trained to care for children with cancer or blood disorders
  • pain management to ease symptoms or manage post-surgery pain
  • steroid therapy to help increase hemoglobin or red blood cells
  • surgery by our board-certified pediatric general surgeons to remove the spleen
  • transfusion services and testing including red blood cell exchange transfusion 
  • transition of care when it’s time for adult care and services
Why Choose Us for Hemolytic Anemia Care

Why Choose Us for Hemolytic Anemia Care


Our renowned hematologists (blood disorder specialists), oncologists (cancer doctors), and researchers in the Nemours Center for Cancer and Blood Disorders (NCCBD) work together with other top specialists to care for children with anemia. To help give kids the best possible care, we’re also actively involved in pediatric research and we offer many opportunities for clinical trial enrollment. 

Learn More About Why to Choose Us » 

Regional Hemolytic Anemia Disease Highlights

Services, programs, facilities and care teams differ at each location. Call for details.

We offer complete care for kids with hemolytic anemia at Nemours/Alfred I. duPont Hospital for Children (Wilmington, Del.) and outpatient appointments at select Nemours duPont Pediatrics locations. 

Our Palliative and Supportive Care Program located at duPont Hospital for Children (Wilmington, Del.) provides compassionate care for families and children coping with life-threatening or life-limiting conditions. 

We offer complete care complete care for kids with hemolytic anemia at Nemours Children’s Hospital (Orlando). Outpatient and follow-up appointments are available at select Nemours Children’s Specialty Care locations.

We offer complete care complete care for kids with hemolytic anemia at Nemours Children’s Specialty Care, Jacksonville (working with Wolfson Children’s Hospital and Mayo Clinic in Jacksonville ). Outpatient and follow-up appointments are available at select Nemours Children’s Specialty Care locations.

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Research & Clinical Trials

At Nemours, we’re actively researching new approaches for childhood disease prevention, diagnosis and treatment.

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KidsHealth Library

Learn more about your child’s medical condition from the experts at Nemours’ KidsHealth.